Acetylpropionylmorphine

Acetylpropionylmorphine is an opiate analogue that is an ester of morphine.wikipedia
17 Related Articles

Designer drug

designer drugsdesigner steroiddesigner
It was developed in the early 1900s after first being synthesised in Great Britain in 1875 but shelved along with heroin and various other esters of morphine, but was never used medically, instead being widely sold as one of the first "designer drugs" for around five years following the introduction of the first international restrictions on the sale of heroin in 1925.
The most notable of these were dibenzoylmorphine and acetylpropionylmorphine, which have virtually identical effects to heroin but were not covered by the Opium Convention.

Opiate

opiatesOpiate drugOpiate pathway
Acetylpropionylmorphine is an opiate analogue that is an ester of morphine.
Nicomorphine (morphine dinicotinate), dipropanoylmorphine (morphine dipropionate), desomorphine (di-hydro-desoxy-morphine), methyldesorphine, acetylpropionylmorphine, dibenzoylmorphine, diacetyldihydromorphine, and several others are also derived from morphine.

Heroin

diamorphinediacetylmorphinesmack
It was developed in the early 1900s after first being synthesised in Great Britain in 1875 but shelved along with heroin and various other esters of morphine, but was never used medically, instead being widely sold as one of the first "designer drugs" for around five years following the introduction of the first international restrictions on the sale of heroin in 1925.
Two other 3,6 diesters of morphine invented in 1874–75 along with diamorphine, dibenzoylmorphine and acetylpropionylmorphine, were made as substitutes after it was outlawed in 1925 and, therefore, sold as the first "designer drugs" until they were outlawed by the League of Nations in 1930.

Dipropanoylmorphine

The drug was first synthesised circa or about 1875 in Great Britain along with many other esters of morphine, all of which were shelved at the time, some of which were later developed such as heroin (1898), acetylpropionylmorphine (1923), dibenzoylmorphine (1900 and/or 1924), and so on.

Morphine

morphiamorphine addictionmorphine sulfate
Acetylpropionylmorphine is an opiate analogue that is an ester of morphine.

Dihydromorphine

It was discovered shortly after the development of dihydromorphine (discovered in nature and/or first synthesised circa 1880, commercially available in 1900), hydromorphone (first synthesised 1924), and oxymorphone (synthesised 1914), that mono, di, tri, and perhaps tetra esters could be developed from them as well.

Hydromorphone

DilaudidPalladonedihydromorphinone
It was discovered shortly after the development of dihydromorphine (discovered in nature and/or first synthesised circa 1880, commercially available in 1900), hydromorphone (first synthesised 1924), and oxymorphone (synthesised 1914), that mono, di, tri, and perhaps tetra esters could be developed from them as well.

Oxymorphone

oxymorphone hydrochlorideOpanaNumorphan
It was discovered shortly after the development of dihydromorphine (discovered in nature and/or first synthesised circa 1880, commercially available in 1900), hydromorphone (first synthesised 1924), and oxymorphone (synthesised 1914), that mono, di, tri, and perhaps tetra esters could be developed from them as well.

Codeine

codeine phosphatecodeine hydrochlorideCod'ine
A smaller number of esters of codeine, hydrocodone, and dihydrocodeine, and one or two of oxycodone are also known and used in medicine.

Hydrocodone

TussionexHycodandihydrocodeinone
A smaller number of esters of codeine, hydrocodone, and dihydrocodeine, and one or two of oxycodone are also known and used in medicine.

Dihydrocodeine

DF118dicodideDihydrocodeine bitartrate
A smaller number of esters of codeine, hydrocodone, and dihydrocodeine, and one or two of oxycodone are also known and used in medicine.

Oxycodone

OxyContinEukodalRoxicodone
A smaller number of esters of codeine, hydrocodone, and dihydrocodeine, and one or two of oxycodone are also known and used in medicine.

Opioid

opioidsopioid-induced constipationopioid analgesic

3,14-Diacetyloxymorphone

Therefore, all or most of this group and its hydromorphone analogues along with some others more closely related to heroin such as acetylpropionylmorphine were the first designer drugs in the 1920s.