A report on Acetylpropionylmorphine

Opiate analogue that is an ester of morphine.

- Acetylpropionylmorphine

3 related topics with Alpha

Overall

Designer drug

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Structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests.

Structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests.

The most notable of these were dibenzoylmorphine and acetylpropionylmorphine, which have virtually identical effects to heroin but were not covered by the Opium Convention.

Heroin paraphernalia in a Jack Daniels tin

Heroin

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Opioid used as a recreational drug for its euphoric effects.

Opioid used as a recreational drug for its euphoric effects.

Heroin paraphernalia in a Jack Daniels tin
Advertising sign from Bayer for use in US drug stores, dating from before the federal prohibition of Heroin in 1924
A 2010 study ranking various illegal and legal drugs based on statements by drug-harm experts. Heroin was found to be the second overall most dangerous drug.
Short-term effects of usage
Long-term effects of intravenous usage, including – and indeed primarily because of – the effects of the contaminants common in illegal heroin and contaminated needles.
Black tar heroin
Advertisement for Bayer Heroin
Bayer Heroin bottle
International drug routes
Afghanistan opium poppy cultivation, 1994–2016 (hectares)
Primary worldwide producers of heroin
Addiction experts in psychiatry, chemistry, pharmacology, forensic science, epidemiology, and the police and legal services engaged in delphic analysis regarding 20 popular recreational drugs. Heroin was ranked 1st in dependence, physical harm, and social harm.
Drug overdoses killed more than 70,200 in the US in 2017, with heroin involved in 15,482 of those deaths.<ref name=NIDA-deaths>{{cite web | url = http://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates | title = Overdose Death Rates | archive-url = https://web.archive.org/web/20151128091723/http://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates | archive-date=28 November 2015 | work = National Institute on Drug Abuse (NIDA) }}</ref>
US yearly overdose deaths involving heroin.<ref name=NIDA-deaths/>
US yearly deaths from all opioid drugs. Included in this number are opioid analgesics, along with heroin and illicit .<ref name=NIDA-deaths/>

Two other 3,6 diesters of morphine invented in 1874–75 along with diamorphine, dibenzoylmorphine and acetylpropionylmorphine, were made as substitutes after it was outlawed in 1925 and, therefore, sold as the first "designer drugs" until they were outlawed by the League of Nations in 1930.

Harvesting the poppy pod.

Opiate

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Substance derived from opium.

Substance derived from opium.

Harvesting the poppy pod.
A chart outlining the structural features that define opiates and opioids, including distinctions between semi-synthetic and fully synthetic opiate structures
Codeine
Chemical structure of morphine
Morphine addiction cure advertisement in the year 1900

Nicomorphine (Vilan, morphine dinicotinate), Diamorphine (Heroin, morphine diacetate), dipropanoylmorphine (morphine dipropionate), desomorphine (Permonid, di-hydro-desoxy-morphine), methyldesorphine, acetylpropionylmorphine, dibenzoylmorphine, diacetyldihydromorphine, and several others are also derived from morphine.