Allergan

Allergan plcAllergan, PlcNaurexAllergan (Zeitiq)Allergan PharmaceuticalsAllergan, Inc.Allergan, India
Allergan plc is an Irish-domiciled pharmaceutical company that acquires, develops, and markets brand name drugs, and in 2017 generated 80% net sales from the U.S. healthcare system.wikipedia
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Tax inversion

corporate inversioncorporate tax inversioncorporate tax inversions
Actavis was a 2013 U.S. tax inversion that moved its legal domicile to Ireland to avoid U.S. taxes.
New US Treasury rules in 2014–16 blocked several major inversions (e.g. 2016 USD$160 billion Pfizer–Allergan plc inversion, and the 2015 USD$54 billion AbbVie–Shire plc inversion), and the Tax Cuts and Jobs Act of 2017 (TCJA) further reduced the taxation incentives of inversions.

Pfizer

Pfizer Inc.Pfizer, Inc.Pfizer Inc
In 2016, the U.S. Treasury blocked Actavis from executing what would have been the largest corporate tax inversion in history, in a $160 billion merger with Pfizer.
In 2016, Pfizer Inc. was expected to merge with Allergan, Plc to create the Ireland-based "Pfizer plc" in a deal that would have been worth $160 billion.

Corporation tax in the Republic of Ireland

corporate tax inversiontax inversioneffective tax rate
Actavis used the Irish low-tax corporate system to acquire large U.S. pharmaceutical firms (e.g. Forest Labs, Allergan Inc.), and redomicile them to Ireland. On October 1, 2013, Actavis acquired Irish–registered Warner Chilcott for $5 billion and used the transaction to execute a corporate tax inversion to Ireland.
Not only did U.S. companies rank ahead of Irish companies, but a material quantum of the gross operating surplus attributed to Irish companies, is from U.S. tax inversion such as Medtronic, Eaton and Allergan, who are in effect, U.S.–controlled multinationals, and have little attachment to Ireland.

Linaclotide

Linzess
The company's products include Botox (botulinum toxin), Namenda (memantine), Restasis (ciclosporin), Linzess (linaclotide), Bystolic (nebivolol), Juvederm (injectable filler), Latisse (bimatoprost), Lo Loestrin Fe, Estrace (estradiol), Teflaro (ceftaroline fosamil), Dalvance (dalbavancin, Ozurdex (dexamethasone), Optive, Natrelle, Viibryd (vilazodone), Liletta (levonorgestrel), Saphris (asenapine), Enablex (darifenacin), Actonel (risedronic acid), Androderm (testosterone), and Gelnique (oxybutynin).
It is priced at around $400 for thirty pills in the US and is marketed by Allergan in most of the world and by Astellas in Asia; Ironwood Pharmaceuticals was the originator.

AbbVie Inc.

AbbVieAbbVie IncStemCentrx
In June 2019, U.S. pharmaceutical company AbbVie announced it had reached an agreement to acquire Allergan for $63 billion; however the transaction would not be structured as a tax inversion, and that post the transaction, the Group would be domiciled in the U.S. for tax purposes.
On 25 June 2019, AbbVie announced it would acquire Irish-based Allergan plc for about $63 billion; however the transaction would not be structured as a tax inversion, and that post the transaction, AbbVie (and the group) would remain legally domiciled in the U.S. for tax purposes.

Botulinum toxin

Botoxbotulinumbotulin
The company's products include Botox (botulinum toxin), Namenda (memantine), Restasis (ciclosporin), Linzess (linaclotide), Bystolic (nebivolol), Juvederm (injectable filler), Latisse (bimatoprost), Lo Loestrin Fe, Estrace (estradiol), Teflaro (ceftaroline fosamil), Dalvance (dalbavancin, Ozurdex (dexamethasone), Optive, Natrelle, Viibryd (vilazodone), Liletta (levonorgestrel), Saphris (asenapine), Enablex (darifenacin), Actonel (risedronic acid), Androderm (testosterone), and Gelnique (oxybutynin).
Based on data from thousands of patients collected by 240 investigators, Allergan received U.S. Food and Drug Administration (FDA) approval in 1989 to market Oculinum for clinical use in the United States to treat adult strabismus and blepharospasm, using the trademark Botox.

David E.I. Pyott

David Edmund Ian Pyott
In 1998, David E.I. Pyott became chief executive officer of the company, a position he held until the merger in 2015.
David Edmund Ian Pyott (born 1953) was the CEO of Allergan, a pharmaceutical company from 1998 to 2015, when Allergan was acquired by Actavis.

Parsippany-Troy Hills, New Jersey

Parsippany-Troy HillsParsippanyParsippany-Troy Hills Township
In 2011, the company moved its corporate headquarters from Corona, California to Parsippany-Troy Hills, New Jersey.
Allergan, B&G Foods, Kings Food Markets, Lexus and Toyota Financial Services, American Financial Resources, Wyndham Worldwide and PNY Technologies, a manufacturer of computer memory devices, are in Parsippany-Troy Hills.

Warner Chilcott

Galen
On October 1, 2013, Actavis acquired Irish–registered Warner Chilcott for $5 billion and used the transaction to execute a corporate tax inversion to Ireland.
On October 1, 2013, the company was acquired by Actavis (now Allergan).

Abbott Medical Optics

Advanced Medical OpticsAdvanced Medical Optics Inc.
In July 2002, the company spun off its ophthalmic surgical and contact lens care businesses into Advanced Medical Optics (now Abbott Medical Optics).
AMO was spun off from Allergan in 2002.

Zeltiq Aesthetics

Zeltiq
On April 28, the company acquired Zeltiq Aesthetics, marketer of a cryolipolysis procedure, for $2.4 billion.
Zeltiq Aesthetics is a subsidiary of Allergan based in Pleasanton, California that markets and licenses devices used for cryolipolysis procedures.

The St. Regis Mohawk Tribe and Restasis patent

In September 2017, the American pharmaceutical company Allergan made a deal with the St. Regis tribe of the Mohawk people to transfer six patents for Restasis eye drops to the tribe.

Smith, Kline & French

Smith, Kline and FrenchSmithKline BeckmanSmith Kline and French
In 1980, it was acquired by SmithKline Beckman for $259 million in 1980.
SmithKline acquired Allergan in 1982, an eye and skincare business, and merged with Beckman Instruments, Inc., a company specialising in diagnostics and measurement instruments and supplies.

Allergan, Inc.

Allergan, IncAllergan IncAllergan
Allergan plc was formed in February 2015 when Irish–registered Actavis plc acquired U.S.–registered Allergan, Inc., and assumed the Allergan name.
It ceased operation in 2015 when it was acquired by Irish-based Activis plc (itself a 2013 U.S. tax inversion to Ireland), who then renamed the group as Allergan plc.

List of biotech and pharmaceutical companies in the New York metropolitan area

Biotech and pharmaceutical companies in the New York metropolitan areabiotechnologyBiotech and pharmaceutical companies in New Jersey

Actavis

Watson PharmaceuticalsActavis plcActivis plc
Allergan plc was formed in February 2015 when Irish–registered Actavis plc acquired U.S.–registered Allergan, Inc., and assumed the Allergan name.
On June 15, 2015, Actavis plc changed its name to Allergan plc, but the company's U.S. and Canadian generics business will continue to operate under the Actavis name.

Medication

pharmaceuticalpharmaceuticalspharmaceutical drug
Allergan plc is an Irish-domiciled pharmaceutical company that acquires, develops, and markets brand name drugs, and in 2017 generated 80% net sales from the U.S. healthcare system.

Central nervous system

CNScentralcentral nervous system (CNS)
Allergan acquires, develops, reprices and markets branded products in six therapeutic areas: aesthetics/dermatology/plastic surgery; neurosciences/CNS; eye care; women’s health and urology; GI and cystic fibrosis; and cardiovascular disease and infectious disease.

Gastrointestinal tract

intestinegastrointestinaldigestive tract
Allergan acquires, develops, reprices and markets branded products in six therapeutic areas: aesthetics/dermatology/plastic surgery; neurosciences/CNS; eye care; women’s health and urology; GI and cystic fibrosis; and cardiovascular disease and infectious disease.

Memantine

Namenda
The company's products include Botox (botulinum toxin), Namenda (memantine), Restasis (ciclosporin), Linzess (linaclotide), Bystolic (nebivolol), Juvederm (injectable filler), Latisse (bimatoprost), Lo Loestrin Fe, Estrace (estradiol), Teflaro (ceftaroline fosamil), Dalvance (dalbavancin, Ozurdex (dexamethasone), Optive, Natrelle, Viibryd (vilazodone), Liletta (levonorgestrel), Saphris (asenapine), Enablex (darifenacin), Actonel (risedronic acid), Androderm (testosterone), and Gelnique (oxybutynin).

Ciclosporin

cyclosporinecyclosporincyclosporin A
The company's products include Botox (botulinum toxin), Namenda (memantine), Restasis (ciclosporin), Linzess (linaclotide), Bystolic (nebivolol), Juvederm (injectable filler), Latisse (bimatoprost), Lo Loestrin Fe, Estrace (estradiol), Teflaro (ceftaroline fosamil), Dalvance (dalbavancin, Ozurdex (dexamethasone), Optive, Natrelle, Viibryd (vilazodone), Liletta (levonorgestrel), Saphris (asenapine), Enablex (darifenacin), Actonel (risedronic acid), Androderm (testosterone), and Gelnique (oxybutynin).

Nebivolol

BystolicNebivilol
The company's products include Botox (botulinum toxin), Namenda (memantine), Restasis (ciclosporin), Linzess (linaclotide), Bystolic (nebivolol), Juvederm (injectable filler), Latisse (bimatoprost), Lo Loestrin Fe, Estrace (estradiol), Teflaro (ceftaroline fosamil), Dalvance (dalbavancin, Ozurdex (dexamethasone), Optive, Natrelle, Viibryd (vilazodone), Liletta (levonorgestrel), Saphris (asenapine), Enablex (darifenacin), Actonel (risedronic acid), Androderm (testosterone), and Gelnique (oxybutynin).

Injectable filler

dermal fillerJuvedermfiller
The company's products include Botox (botulinum toxin), Namenda (memantine), Restasis (ciclosporin), Linzess (linaclotide), Bystolic (nebivolol), Juvederm (injectable filler), Latisse (bimatoprost), Lo Loestrin Fe, Estrace (estradiol), Teflaro (ceftaroline fosamil), Dalvance (dalbavancin, Ozurdex (dexamethasone), Optive, Natrelle, Viibryd (vilazodone), Liletta (levonorgestrel), Saphris (asenapine), Enablex (darifenacin), Actonel (risedronic acid), Androderm (testosterone), and Gelnique (oxybutynin).

Bimatoprost

LatisseLumigan
The company's products include Botox (botulinum toxin), Namenda (memantine), Restasis (ciclosporin), Linzess (linaclotide), Bystolic (nebivolol), Juvederm (injectable filler), Latisse (bimatoprost), Lo Loestrin Fe, Estrace (estradiol), Teflaro (ceftaroline fosamil), Dalvance (dalbavancin, Ozurdex (dexamethasone), Optive, Natrelle, Viibryd (vilazodone), Liletta (levonorgestrel), Saphris (asenapine), Enablex (darifenacin), Actonel (risedronic acid), Androderm (testosterone), and Gelnique (oxybutynin).

Estradiol

17β-estradioloestradiol17-β-estradiol
The company's products include Botox (botulinum toxin), Namenda (memantine), Restasis (ciclosporin), Linzess (linaclotide), Bystolic (nebivolol), Juvederm (injectable filler), Latisse (bimatoprost), Lo Loestrin Fe, Estrace (estradiol), Teflaro (ceftaroline fosamil), Dalvance (dalbavancin, Ozurdex (dexamethasone), Optive, Natrelle, Viibryd (vilazodone), Liletta (levonorgestrel), Saphris (asenapine), Enablex (darifenacin), Actonel (risedronic acid), Androderm (testosterone), and Gelnique (oxybutynin).