A report on Hyperammonemia, Hepatic encephalopathy and Ammonia
Hyperammonemia is a metabolic disturbance characterised by an excess of ammonia in the blood.
- HyperammonemiaThe underlying mechanism is believed to involve the buildup of ammonia in the blood, a substance that is normally removed by the liver.
- Hepatic encephalopathyHyperammonemia is one of the metabolic derangements that contribute to hepatic encephalopathy, which can cause swelling of astrocytes and stimulation of NMDA-receptors in the brain.
- HyperammonemiaSerum ammonia levels are elevated in 90% of people, but not all hyperammonaemia (high ammonia levels in the blood) is associated with encephalopathy.
- Hepatic encephalopathyLiver dysfunction, such as that seen in cirrhosis, may lead to elevated amounts of ammonia in the blood (hyperammonemia).
- AmmoniaHyperammonemia contributes to the confusion and coma of hepatic encephalopathy, as well as the neurologic disease common in people with urea cycle defects and organic acidurias.
- Ammonia0 related topics with Alpha