Analgesic

analgesiaanalgesicspainkillerspainkillerpain medicationpain medicationspain reliefpain relieverantinociceptionpain killer
An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.wikipedia
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Morphine

morphiamorphine addictionmorphine sulfate
Analgesics include paracetamol (known in North America as acetaminophen or simply APAP), the nonsteroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, and opioid drugs such as morphine and oxycodone. Morphine, the archetypal opioid, and other opioids (e.g., codeine, oxycodone, hydrocodone, dihydromorphine, pethidine) all exert a similar influence on the cerebral opioid receptor system.
Morphine is a pain medication of the opiate family which is found naturally in a number of plants and animals.

Paracetamol

acetaminophenPanadolTylenol PM
Analgesics include paracetamol (known in North America as acetaminophen or simply APAP), the nonsteroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, and opioid drugs such as morphine and oxycodone.
It is classified as a mild analgesic.

Medication

pharmaceuticalpharmaceuticalspharmaceutical drug
An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.

Pain

physical painacute painnociceptive pain
An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.
Episodic analgesia may occur under special circumstances, such as in the excitement of sport or war: a soldier on the battlefield may feel no pain for many hours from a traumatic amputation or other severe injury.

Anesthetic

anaestheticanestheticsanaesthetics
They are distinct from anesthetics, which temporarily affect, and in some instances completely eliminate, sensation.
Anesthetics are distinct from analgesics, which block only sensation of painful stimuli.

Oxycodone

OxyContinEukodalRoxicodone
Analgesics include paracetamol (known in North America as acetaminophen or simply APAP), the nonsteroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, and opioid drugs such as morphine and oxycodone. Morphine, the archetypal opioid, and other opioids (e.g., codeine, oxycodone, hydrocodone, dihydromorphine, pethidine) all exert a similar influence on the cerebral opioid receptor system.
The approved uses is for relief of cancer pain, trauma pain, or pain due to major surgery, in children already treated with opioids, who can tolerate at least 20 mg per day of oxycodone; this provides an alternative to Duragesic (fentanyl), the only other extended-release opioid analgesic approved for children.

Opioid

opioidsopioid-induced constipationopioid analgesic
Analgesics include paracetamol (known in North America as acetaminophen or simply APAP), the nonsteroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, and opioid drugs such as morphine and oxycodone. Morphine, the archetypal opioid, and other opioids (e.g., codeine, oxycodone, hydrocodone, dihydromorphine, pethidine) all exert a similar influence on the cerebral opioid receptor system.
Used medically, approaching toxicity goes unrecognized because the pain medication effect ends long before the drug's elimination half-life.

Pethidine

meperidineDemerolPethidine/meperidine
Morphine, the archetypal opioid, and other opioids (e.g., codeine, oxycodone, hydrocodone, dihydromorphine, pethidine) all exert a similar influence on the cerebral opioid receptor system.
Pethidine, also known as meperidine and sold under the brand name Demerol among others, is a synthetic opioid pain medication of the phenylpiperidine class.

Tramadol

UltramUltracetUltram ER
Buprenorphine is a partial agonist of the μ-opioid receptor, and tramadol is a serotonin norepinephrine reuptake inhibitor (SNRI) with weak μ-opioid receptor agonist properties.
Tramadol, sold under the brand name Ultram among others, is an opioid pain medication used to treat moderate to moderately severe pain.

Tapentadol

Nucynta
Tapentadol, with some structural similarities to tramadol, presents what is believed to be a novel drug working through two (and possibly three) different modes of action in the fashion of both a traditional opioid and as an SNRI.
Tapentadol, brand names Nucynta among others, is a centrally acting opioid analgesic of the benzenoid class with a dual mode of action as an agonist of the μ-opioid receptor and as a norepinephrine reuptake inhibitor (NRI).

Dihydromorphine

Morphine, the archetypal opioid, and other opioids (e.g., codeine, oxycodone, hydrocodone, dihydromorphine, pethidine) all exert a similar influence on the cerebral opioid receptor system.
Dihydromorphine is a moderately strong analgesic and is used clinically in the treatment of pain and also is an active metabolite of the analgesic opioid drug dihydrocodeine.

Antipyretic

febrifugeantipyreticsanti-pyretic
Nonsteroidal anti-inflammatory drugs (usually abbreviated to NSAIDs), are a drug class that groups together drugs that decrease pain and lower fever, and, in higher doses decrease inflammation.
The most common antipyretics in the United States are ibuprofen and aspirin, which are nonsteroidal anti-inflammatory drugs (NSAIDs) used primarily as analgesics (pain relievers), but which also have antipyretic properties; and acetaminophen (paracetamol), an analgesic with weak anti-inflammatory properties.

Antiemetic

antiemeticsanti-emeticanti-emetics
Patients starting morphine may experience nausea and vomiting (generally relieved by a short course of antiemetics such as phenergan).
Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer.

Nonsteroidal anti-inflammatory drug

NSAIDNSAIDsnon-steroidal anti-inflammatory drug
Analgesics include paracetamol (known in North America as acetaminophen or simply APAP), the nonsteroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, and opioid drugs such as morphine and oxycodone.
Nonsteroidal anti-inflammatory drugs (NSAIDs) are members of a drug class that reduces pain, decreases fever, prevents blood clots, and in higher doses, decreases inflammation.

Ketamine

K-holeSpecial KCalypsol
Other psychotropic analgesic agents include ketamine (an NMDA receptor antagonist), clonidine and other α 2 -adrenoreceptor agonists, and mexiletine and other local anaesthetic analogues.
It induces a trance-like state while providing pain relief, sedation, and memory loss.

Nefopam

Adjuvant analgesics, also called atypical analgesics, include nefopam, orphenadrine, pregabalin, gabapentin, cyclobenzaprine, hyoscine (scopolamine), and other drugs possessing anticonvulsant, anticholinergic, and/or antispasmodic properties, as well as many other drugs with CNS actions.
Nefopam, sold under the brand names Acupan and nefopam medisol among others, is a painkilling medication.

Ketobemidone

Cetobemidone
Some analgesics such as methadone and ketobemidone and perhaps piritramide have intrinsic NMDA action.
Ketobemidone, sold under the brand name Ketogan among others, is a powerful synthetic opioid painkiller.

Opioid-induced hyperalgesia

opiates
Opioid tolerance should not be confused with opioid-induced hyperalgesia.
In addition, what appears to be opioid tolerance can be caused by opioid-induced hyperalgesia lowering the baseline pain level, thus masking the drug's analgesic effects.

Piritramide

Some analgesics such as methadone and ketobemidone and perhaps piritramide have intrinsic NMDA action.
Piritramide (R-3365, trade names Dipidolor, Piridolan, Pirium and others) is a synthetic opioid analgesic (narcotic painkiller) that is marketed in certain European countries including: Austria, Belgium, Czech Republic, Germany and the Netherlands.

Buprenorphine

SubutexSuboxoneProbuphine
Buprenorphine is a partial agonist of the μ-opioid receptor, and tramadol is a serotonin norepinephrine reuptake inhibitor (SNRI) with weak μ-opioid receptor agonist properties.
It is difficult to achieve acute opioid analgesia in persons using buprenorphine for opioid replacement therapy.

Methadone

Methadone treatmentAmidonAmidones
Some analgesics such as methadone and ketobemidone and perhaps piritramide have intrinsic NMDA action.
Methadone is used as an analgesic in chronic pain, often in rotation with other opioids.

Migraine

migrainesmigraine headachemigraine headaches
It is used in Europe for moderate to strong pain, as well as its migraine-treating and muscle-relaxant properties.
Initial recommended treatment is with simple pain medication such as ibuprofen and paracetamol (acetaminophen) for the headache, medication for the nausea, and the avoidance of triggers.

Ethanol

alcoholbioethanolethyl alcohol
High-alcohol liquor, two forms of which were found in the US Pharmacopoeia up until 1916 and in common use by physicians well into the 1930s, has been used in the past as an agent for dulling pain, due to the CNS depressant effects of ethyl alcohol, a notable example being the American Civil War.
Liquid preparations of pain medications, cough and cold medicines, and mouth washes, for example, may contain up to 25% ethanol and may need to be avoided in individuals with adverse reactions to ethanol such as alcohol-induced respiratory reactions.

Flupirtine

Flupirtine is a centrally acting K+ channel opener with weak NMDA antagonist properties.
Flupirtine is an aminopyridine that functions as a centrally acting non-opioid analgesic that was originally used as an analgesic for acute and chronic pain but in 2013 due to issues with liver toxicity, the European Medicines Agency restricted its use to acute pain, for no more than two weeks, and only for people who cannot use other painkillers.

Methylphenidate

RitalinConcertaMethylin
Stimulants such as methylphenidate, caffeine, ephedrine, dextroamphetamine, methamphetamine, and cocaine work against heavy sedation and may elevate mood in distressed patients as do the antidepressants.
Stimulants may have fewer side-effects than tricyclic antidepressants in the elderly and medically ill. In individuals with terminal cancer, methylphenidate can be used to counteract opioid-induced somnolence, to increase the analgesic effects of opioids, to treat depression, and to improve cognitive function.