Analgesic nephropathy

analgesicNSAID
Analgesic nephropathy is injury to the kidneys caused by analgesic medications such as aspirin, phenacetin, and paracetamol.wikipedia
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Interstitial nephritis

tubulointerstitial nephritisacute interstitial nephritisTubulo-interstitial nephritis
The specific kidney injuries induced by analgesics are renal papillary necrosis and chronic interstitial nephritis. Found in the renal pelvis, ureter, and capillaries supplying the nephrons, capillary sclerosis is thought to lead to renal papillary necrosis and, in turn, chronic interstitial nephritis.
Common causes include infection, or reaction to medication such as an analgesic or antibiotics such as methicillin (meticillin).

Renal papillary necrosis

Acute papillary necrosiskidney papillary necrosismedullary necrosis
The specific kidney injuries induced by analgesics are renal papillary necrosis and chronic interstitial nephritis. Found in the renal pelvis, ureter, and capillaries supplying the nephrons, capillary sclerosis is thought to lead to renal papillary necrosis and, in turn, chronic interstitial nephritis.
Analgesic nephropathy is a common cause of renal papillary necrosis.

Paracetamol

acetaminophenPanadolTylenol PM
Analgesic nephropathy is injury to the kidneys caused by analgesic medications such as aspirin, phenacetin, and paracetamol. They include aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs), as well as the antipyretics paracetamol (known as acetaminophen in the United States) and phenacetin.
This was accompanied by the commercial demise of phenacetin, blamed as the cause of analgesic nephropathy and hematological toxicity.

Phenacetin

Acetophenetidinacetophenetidineacetphentidin
Analgesic nephropathy is injury to the kidneys caused by analgesic medications such as aspirin, phenacetin, and paracetamol. They include aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs), as well as the antipyretics paracetamol (known as acetaminophen in the United States) and phenacetin.
Chronic use of phenacetin is known to lead to analgesic nephropathy characterized by renal papillary necrosis.

Nonsteroidal anti-inflammatory drug

NSAIDNSAIDsnon-steroidal anti-inflammatory drug
They include aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs), as well as the antipyretics paracetamol (known as acetaminophen in the United States) and phenacetin.
NSAIDs in combination with excessive use of phenacetin or paracetamol (acetaminophen) may lead to analgesic nephropathy.

Kidney

kidneysrenalkidney disorder
Analgesic nephropathy is injury to the kidneys caused by analgesic medications such as aspirin, phenacetin, and paracetamol.

Analgesic

analgesiaanalgesicspainkillers
Analgesic nephropathy is injury to the kidneys caused by analgesic medications such as aspirin, phenacetin, and paracetamol.

Aspirin

acetylsalicylic acidBufferinASA
Analgesic nephropathy is injury to the kidneys caused by analgesic medications such as aspirin, phenacetin, and paracetamol. They include aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs), as well as the antipyretics paracetamol (known as acetaminophen in the United States) and phenacetin.

Renal blood flow

renal plasma flowblood flow to the kidneykidney blood flow
They appear to result from decreased blood flow to the kidney, rapid consumption of antioxidants, and subsequent oxidative damage to the kidney.

Antioxidant

antioxidantsanti-oxidantantioxidative
They appear to result from decreased blood flow to the kidney, rapid consumption of antioxidants, and subsequent oxidative damage to the kidney.

Oxidative stress

oxidative damageoxidant stressoxidative
They appear to result from decreased blood flow to the kidney, rapid consumption of antioxidants, and subsequent oxidative damage to the kidney.

Clinical urine tests

urinalysisurine testurine sample
This kidney damage may lead to progressive chronic kidney failure, abnormal urinalysis results, high blood pressure, and anemia.

Hypertension

high blood pressurehypertensivearterial hypertension
This kidney damage may lead to progressive chronic kidney failure, abnormal urinalysis results, high blood pressure, and anemia. Common findings in people with analgesic nephropathy include headache, anemia, high blood pressure (hypertension), and white blood cells in the urine (pyuria).

Anemia

anaemiaanemicanaemic
This kidney damage may lead to progressive chronic kidney failure, abnormal urinalysis results, high blood pressure, and anemia. Common findings in people with analgesic nephropathy include headache, anemia, high blood pressure (hypertension), and white blood cells in the urine (pyuria).

Chronic kidney disease

chronic renal failureend-stage renal diseasechronic kidney failure
This kidney damage may lead to progressive chronic kidney failure, abnormal urinalysis results, high blood pressure, and anemia. Complications of analgesic nephropathy include pyelonephritis and end-stage kidney disease.

Europe

EuropeanEUEuropean continent
Analgesic nephropathy was once a common cause of kidney injury and end-stage kidney disease in parts of Europe, Australia, and the United States.

Australia

AUSAustralianCommonwealth of Australia
Analgesic nephropathy was once a common cause of kidney injury and end-stage kidney disease in parts of Europe, Australia, and the United States.

United States

AmericanU.S.USA
Analgesic nephropathy was once a common cause of kidney injury and end-stage kidney disease in parts of Europe, Australia, and the United States.

Headache

headacheschronic headacheheadach
Common findings in people with analgesic nephropathy include headache, anemia, high blood pressure (hypertension), and white blood cells in the urine (pyuria).

Pyuria

leukocyturiapus in the urinesterile pyuria
Common findings in people with analgesic nephropathy include headache, anemia, high blood pressure (hypertension), and white blood cells in the urine (pyuria).

Proteinuria

protein in the urineproteinIsolated proteinuria
Some individuals with analgesic nephropathy may also have protein in their urine (proteinuria).

Pyelonephritis

kidney infectionpyelitisurosepsis
Complications of analgesic nephropathy include pyelonephritis and end-stage kidney disease.

Urinary system

urinary tracturinaryrenal system
Analgesic nephropathy also appears to increase the risk of developing cancers of the urinary system.

Renal pelvis

pyelo-kidney pelvispelvic
Found in the renal pelvis, ureter, and capillaries supplying the nephrons, capillary sclerosis is thought to lead to renal papillary necrosis and, in turn, chronic interstitial nephritis.

Ureter

uretersureteralureteropelvic junction
Found in the renal pelvis, ureter, and capillaries supplying the nephrons, capillary sclerosis is thought to lead to renal papillary necrosis and, in turn, chronic interstitial nephritis.