A report on Anterograde amnesia and Zopiclone

Hippocampus (brain)
A 7.5 mg zopiclone tablet.
Two major zopiclone metabolites.

This has also been recorded in non-benzodiazepine sedatives or "z-drugs" which act on the same set of receptors; such as zolpidem (also known as Ambien), eszopiclone (also known as Lunesta), and zopiclone (also known by brand names Imovane and Zimovane).

- Anterograde amnesia

Long-term use of sedative-hypnotics for insomnia lacks an evidence base and is discouraged for reasons that include concerns about such potential adverse drug effects as cognitive impairment (anterograde amnesia), daytime sedation, motor incoordination, and increased risk of motor vehicle accidents and falls.

- Zopiclone
Hippocampus (brain)

2 related topics with Alpha

Overall

Eszopiclone

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Medication used in the treatment of insomnia.

Medication used in the treatment of insomnia.

It is the S-stereoisomer of zopiclone.

Long-term use of sedative-hypnotics for insomnia lacks an evidence base and has traditionally been discouraged for reasons that include concerns about such potential adverse drug effects as cognitive impairment (anterograde amnesia), daytime sedation, motor incoordination, and increased risk of motor vehicle accidents and falls.

Chemical structure of the prototypical Z-drug zolpidem

Nonbenzodiazepine

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Nonbenzodiazepines, sometimes referred to colloquially as Z-drugs (as many of them begin with the letter "z"), are a class of psychoactive drugs that are very benzodiazepine-like in nature.

Nonbenzodiazepines, sometimes referred to colloquially as Z-drugs (as many of them begin with the letter "z"), are a class of psychoactive drugs that are very benzodiazepine-like in nature.

Chemical structure of the prototypical Z-drug zolpidem
Core structures of selected nonbenzodiazepines (left three diagrams) and the structure of benzodiazepines (right) for comparison

Zopiclone (Imovane, Zimovane, Somnol, etc.)

Long-term use of sedative-hypnotics for insomnia lacks an evidence base and is discouraged for reasons that include concerns about such potential adverse drug effects as cognitive impairment (anterograde amnesia), daytime sedation, motor incoordination, and increased risk of motor vehicle accidents and falls.