Anterograde amnesia

Hippocampus (brain)

Loss of the ability to create new memories after the event that caused amnesia, leading to a partial or complete inability to recall the recent past, while long-term memories from before the event remain intact.

- Anterograde amnesia
Hippocampus (brain)

37 related topics

Alpha

Chemical structure of the prototypical Z-drug zolpidem

Nonbenzodiazepine

Nonbenzodiazepines, sometimes referred to colloquially as Z-drugs (as many of them begin with the letter "z"), are a class of psychoactive drugs that are very benzodiazepine-like in nature.

Nonbenzodiazepines, sometimes referred to colloquially as Z-drugs (as many of them begin with the letter "z"), are a class of psychoactive drugs that are very benzodiazepine-like in nature.

Chemical structure of the prototypical Z-drug zolpidem
Core structures of selected nonbenzodiazepines (left three diagrams) and the structure of benzodiazepines (right) for comparison

Long-term use of sedative-hypnotics for insomnia lacks an evidence base and is discouraged for reasons that include concerns about such potential adverse drug effects as cognitive impairment (anterograde amnesia), daytime sedation, motor incoordination, and increased risk of motor vehicle accidents and falls.

A drawing of someone with insomnia from the 14th century

Eszopiclone

Medication used in the treatment of insomnia.

Medication used in the treatment of insomnia.

A drawing of someone with insomnia from the 14th century

Long-term use of sedative-hypnotics for insomnia lacks an evidence base and has traditionally been discouraged for reasons that include concerns about such potential adverse drug effects as cognitive impairment (anterograde amnesia), daytime sedation, motor incoordination, and increased risk of motor vehicle accidents and falls.

Temazepam under the brand name Temtabs 10 mg tablets in Australia.

Temazepam

Medication of the benzodiazepine class used to treat insomnia.

Medication of the benzodiazepine class used to treat insomnia.

Temazepam under the brand name Temtabs 10 mg tablets in Australia.
Generic temazepam 10 mg tablets
Prepn: S. C. Bell, (1965 to Am. Home. Prod.). See also: E. Reeder et al., and  (1967, 1968, both to Hoffmann-La Roche).
Apro temazepam
Normison (temazepam) 10 mg tablets

Anterograde amnesia may also develop, as may respiratory depression in higher doses.

Alprazolam

Fast-acting tranquilizer of medium duration in the triazolobenzodiazepine class, which are benzodiazepines (BZDs) fused with a triazole ring.

Fast-acting tranquilizer of medium duration in the triazolobenzodiazepine class, which are benzodiazepines (BZDs) fused with a triazole ring.

Alprazolam pills in boxes, as sold in France. Both Xanax (original Pfizer alprazolam product) and various generic forms of alprazolam are depicted here.
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Side effects from alprazolam
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Binding at the α1β3γ2 GABAA receptor. Alprazolam with red space-filling carbon atoms. γ2 receptor subunit in mint green. The α1' subunit is hidden.
Alprazolam is metabolized into 4-hydroxyalprazolam (top) and α-hydroxyalprazolam (bottom).

Anterograde amnesia and concentration problems

0.5 mg tablets of the Ativan brand of lorazepam

Lorazepam

Benzodiazepine medication.

Benzodiazepine medication.

0.5 mg tablets of the Ativan brand of lorazepam
1987 advertisement. "In a world where certainties are few...no wonder Ativan is prescribed by so many caring clinicians."

It is also used during surgery to interfere with memory formation and to sedate those who are being mechanically ventilated.

Midazolam

Benzodiazepine medication used for anesthesia, procedural sedation, trouble sleeping, and severe agitation.

Benzodiazepine medication used for anesthesia, procedural sedation, trouble sleeping, and severe agitation.

Injectable midazolam in 1 and 5 mg/ml strengths
Oklahoma State Penitentiary, the site of the state of Oklahoma's execution chamber

It works by inducing sleepiness, decreasing anxiety, and causing a loss of ability to create new memories.

Thiamine

Korsakoff syndrome

Disorder of the central nervous system characterized by amnesia, deficits in explicit memory, and confabulation.

Disorder of the central nervous system characterized by amnesia, deficits in explicit memory, and confabulation.

Thiamine

1) anterograde amnesia, memory loss for events after the onset of the syndrome

A 7.5 mg zopiclone tablet.

Zopiclone

Nonbenzodiazepine used to treat difficulty sleeping.

Nonbenzodiazepine used to treat difficulty sleeping.

A 7.5 mg zopiclone tablet.
Two major zopiclone metabolites.

Long-term use of sedative-hypnotics for insomnia lacks an evidence base and is discouraged for reasons that include concerns about such potential adverse drug effects as cognitive impairment (anterograde amnesia), daytime sedation, motor incoordination, and increased risk of motor vehicle accidents and falls.

Rohypnol 1 mg tablets.

Flunitrazepam

Benzodiazepine used to treat severe insomnia and assist with anesthesia.

Benzodiazepine used to treat severe insomnia and assist with anesthesia.

Rohypnol 1 mg tablets.
Hypnodorm 1 mg flunitrazepam tablets, Australia
Rohypnol
Icelandic Flunitrazepam

This may appear as lack of concentration, confusion and anterograde amnesia—the inability to create memories while under the influence.

Transiente globale Amnesie MRT DWI axial

Transient global amnesia

Neurological disorder whose key defining characteristic is a temporary but almost total disruption of short-term memory with a range of problems accessing older memories.

Neurological disorder whose key defining characteristic is a temporary but almost total disruption of short-term memory with a range of problems accessing older memories.

Transiente globale Amnesie MRT DWI axial

Both TGA and anterograde amnesia deal with disruptions of short-term memory.