Illustrated schematic of IVF with single-sperm injection (ICSI)
AMH bound to its type II receptor, AMHR2 (PDB: 7L0J)
A triple-line endometrium is associated with better IVF outcomes.
A depiction of the procedure of in-vitro fertilisation.
Demonstration of IVF
Normal Vaginal Canal Vs Menopause
Schematic illustration of artificial insemination.

AMH is a predictor for ovarian response in in vitro fertilization (IVF).

- Anti-Müllerian hormone

Anti-Müllerian hormone levels, with higher levels indicating higher chances of pregnancy, as well as of live birth after IVF, even after adjusting for age.

- In vitro fertilisation
Illustrated schematic of IVF with single-sperm injection (ICSI)

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Alpha

Nomogram for the starting dosage of FSH preparation as estimated from age, antral follicle count (AFC) and endogenous serum FSH taken day 3 of the menstrual cycle. An example is given in the nomogram, wherein an age of 32 years and an AFC of 12 gives a point on the middle line that, when continued to an FSH of 5 IU/l, results in a starting FSH dosage of almost 200 IU/l.

Controlled ovarian hyperstimulation

Technique used in assisted reproduction involving the use of fertility medications to induce ovulation by multiple ovarian follicles.

Technique used in assisted reproduction involving the use of fertility medications to induce ovulation by multiple ovarian follicles.

Nomogram for the starting dosage of FSH preparation as estimated from age, antral follicle count (AFC) and endogenous serum FSH taken day 3 of the menstrual cycle. An example is given in the nomogram, wherein an age of 32 years and an AFC of 12 gives a point on the middle line that, when continued to an FSH of 5 IU/l, results in a starting FSH dosage of almost 200 IU/l.
Nomogram for the starting dosage of FSH as estimated from age, anti-Müllerian hormone (AMH) and endogenous serum FSH taken day 3 of the menstrual cycle (same as previous nomogram but with AMH instead of AFC).

These multiple follicles can be taken out by oocyte retrieval (egg collection) for use in in vitro fertilisation (IVF), or be given time to ovulate, resulting in superovulation which is the ovulation of a larger-than-normal number of eggs, generally in the sense of at least two.

Circulating anti-Müllerian hormone (AMH) can predict excessive and poor response to ovarian stimulation. According to NICE guidelines of in vitro fertilization, an anti-Müllerian hormone level of less than or equal to 5.4 pmol/l (0.8 ng/mL) predicts a low response to ovarian hyperstimulation, while a level greater than or equal to 25.0 pmol/l (3.6 ng/mL) predicts a high response. For predicting an excessive response, AMH has a sensitivity and specificity of 82% and 76%, respectively. Overall it may be superior to AFC and basal FSH. Tailoring the dosage of gonadotrophin administration to AMH level has been shown to reduce the incidence of excessive response and cancelled cycles.