Anticonvulsant

anticonvulsantsantiepilepticantiepileptic drugsanti-convulsantanti-seizure medicationantiepilepticsanti-epileptic drugsantiepileptic druganti-seizure medicationsanticonvulsant medication
Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.wikipedia
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Bipolar disorder

bipolarmanic depressionmanic depressive
Anticonvulsants are also increasingly being used in the treatment of bipolar disorder and borderline personality disorder, since many seem to act as mood stabilizers, and for the treatment of neuropathic pain.
Mood stabilizers may improve mood disturbances, and include lithium and certain anticonvulsants such as valproate and carbamazepine.

Epileptic seizure

seizureseizuresepileptic seizures
Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.
A first seizure generally does not require long term treatment with anti-seizure medications unless a specific problem is found on electroencephalogram (EEG) or brain imaging.

Stiripentol

* Stiripentol (2001 – limited availability).
Stiripentol (marketed as Diacomit by Laboratoires Biocodex) is an anticonvulsant drug used in the treatment of epilepsy.

Barbiturate

barbituratesbarbiturate withdrawalsleeping pill
Barbiturates are drugs that act as central nervous system (CNS) depressants, and by virtue of this they produce a wide spectrum of effects, from mild sedation to anesthesia.
Barbiturates are effective as anxiolytics, hypnotics, and anticonvulsants, but have physical and psychological addiction potential as well as overdose potential among other possible adverse effects.

Mood stabilizer

mood stabilizersmood-stabilizingmood stabiliser
Anticonvulsants are also increasingly being used in the treatment of bipolar disorder and borderline personality disorder, since many seem to act as mood stabilizers, and for the treatment of neuropathic pain.
Many agents described as "mood stabilizers" are also categorized as anticonvulsants.

Neuropathic pain

neuropathicpaincentral neuropathic pain
Anticonvulsants are also increasingly being used in the treatment of bipolar disorder and borderline personality disorder, since many seem to act as mood stabilizers, and for the treatment of neuropathic pain.
Favored treatments are certain antidepressants (tricyclic antidepressants and serotonin–norepinephrine reuptake inhibitors), anticonvulsants (pregabalin and gabapentin), and topical lidocaine.

Dravet syndrome

Severe myoclonic epilepsy of infancyDravetDravet's syndrome
Indicated for the treatment of Dravet syndrome.
It is treated with anticonvulsant medications.

Primidone

Mysoline
* Primidone (1952).
Primidone is an anticonvulsant of the barbiturate class.

Depressant

depressantsdownerscentral depressant
Barbiturates are drugs that act as central nervous system (CNS) depressants, and by virtue of this they produce a wide spectrum of effects, from mild sedation to anesthesia.
When depressants are used, effects often include ataxia, anxiolysis, pain relief, sedation or somnolence, and cognitive/memory impairment, as well as in some instances euphoria, dissociation, muscle relaxation, lowered blood pressure or heart rate, respiratory depression, and anticonvulsant effects, and even similar effects of General Anaesthesia and/or death at high doses.

Phenobarbital

phenobarbitoneLuminalHaplos
According to guidelines by the American Academy of Neurology and American Epilepsy Society, mainly based on a major article review in 2004, patients with newly diagnosed epilepsy who require treatment can be initiated on standard anticonvulsants such as carbamazepine, phenytoin, valproic acid/valproate semisodium, phenobarbital, or on the newer anticonvulsants gabapentin, lamotrigine, oxcarbazepine or topiramate.
Phenobarbital was discovered in 1912 and is the oldest still commonly used anti-seizure medication.

Epilepsy

epilepticseizure disorderepilepsies
Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.
Identifying an epilepsy syndrome is useful as it helps determine the underlying causes as well as what anti-seizure medication should be tried.

Nitrazepam

Mogadonserum
Nitrazepam, temazepam, and especially nimetazepam are powerful anticonvulsant agents, however their use is rare due to an increased incidence of side effects and strong sedative and motor-impairing properties.
It also has sedative (calming) properties, as well as amnestic (inducing forgetfulness), anticonvulsant, and skeletal muscle relaxant effects.

Clobazam

FrisiumOnfiTapclob
Clobazam was originally marketed as an anxioselective anxiolytic since 1970 and an anticonvulsant since 1984.

Clorazepate

clorazepate dipotassiumTranxeneClorazepic Acid
It possesses anxiolytic, anticonvulsant, sedative, hypnotic, and skeletal muscle relaxant properties.

Anxiolytic

anxiolysisanti-anxietyanxiolytics
The benzodiazepines are a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and muscle relaxant properties.
Like other benzodiazepines, it possesses anxiolytic properties, but, unlike other benzodiazepines, it does not have anticonvulsant, sedative, skeletal muscle relaxant, motor skill-impairing, or amnestic properties.

Medication

pharmaceuticalpharmaceuticalspharmaceutical drug
Barbiturates are drugs that act as central nervous system (CNS) depressants, and by virtue of this they produce a wide spectrum of effects, from mild sedation to anesthesia. The benzodiazepines are a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and muscle relaxant properties.
Drugs affecting the central nervous system include: Psychedelics, hypnotics, anaesthetics, antipsychotics, eugeroics, antidepressants (including tricyclic antidepressants, monoamine oxidase inhibitors, lithium salts, and selective serotonin reuptake inhibitors (SSRIs)), antiemetics, Anticonvulsants/antiepileptics, anxiolytics, barbiturates, movement disorder (e.g., Parkinson's disease) drugs, stimulants (including amphetamines), benzodiazepines, cyclopyrrolones, dopamine antagonists, antihistamines, cholinergics, anticholinergics, emetics, cannabinoids, and 5-HT (serotonin) antagonists.

Paraldehyde

trioxane
* Paraldehyde (1882).
It is a central nervous system depressant and was soon found to be an effective anticonvulsant, hypnotic and sedative.

SV2A

synaptic vesicle glycoprotein 2A
Additional targets include voltage-gated calcium channels, SV2A, and α2δ.
The protein is targeted by the anti-epileptic drugs (anticonvulsants) levetiracetam and brivaracetam.

Carbamazepine

TegretolEpitolAtretol
According to guidelines by the American Academy of Neurology and American Epilepsy Society, mainly based on a major article review in 2004, patients with newly diagnosed epilepsy who require treatment can be initiated on standard anticonvulsants such as carbamazepine, phenytoin, valproic acid/valproate semisodium, phenobarbital, or on the newer anticonvulsants gabapentin, lamotrigine, oxcarbazepine or topiramate.
Carbamazepine (CBZ), sold under the trade name Tegretol among others, is an anticonvulsant medication used primarily in the treatment of epilepsy and neuropathic pain.

GABA transaminase

GABA-TGABA-transaminase deficiency
Next to the voltage-gated sodium channels and components of the GABA system, their targets include GABA A receptors, the GAT-1 GABA transporter, and GABA transaminase.
GABA transaminase is targeted by multiple antiepileptic and analgesic drugs referred to as GABA transaminase inhibitors.

Potassium bromide

KBrbromidebromide of potassium
* Potassium bromide (1857).
Potassium bromide (KBr) is a salt, widely used as an anticonvulsant and a sedative in the late 19th and early 20th centuries, with over-the-counter use extending to 1975 in the US.

Felbamate

Felbatol
* Felbamate (1993).
Felbamate (marketed under the brand name Felbatol by MedPointe) is an anticonvulsant used in the treatment of epilepsy.

Nimetazepam

Nitrazepam, temazepam, and especially nimetazepam are powerful anticonvulsant agents, however their use is rare due to an increased incidence of side effects and strong sedative and motor-impairing properties.
Nimetazepam is also an anticonvulsant.

Tiagabine

Gabitril
Tiagabine (trade name Gabitril) is an anticonvulsant medication produced by Cephalon that is used in the treatment of epilepsy.

Status epilepticus

super-refractory status epilepticusnonconvulsive status epilepticusprolonged seizures
It is still used to treat status epilepticus, particularly where there are no resuscitation facilities.