Antidepressant

antidepressantsanti-depressantanti-depressantsantidepressant drugsantidepressant medicationrapid-acting antidepressantantidepressant drugantidepressant medicationsantidepressant therapy antidepressants
Antidepressants are medications used to treat major depressive disorder, some anxiety disorders, some chronic pain conditions, and to help manage some addictions.wikipedia
1,230 Related Articles

Antidepressant discontinuation syndrome

withdrawal syndromediscontinuation syndromeSSRI discontinuation syndrome
A discontinuation syndrome can occur after stopping any antidepressant which resembles recurrent depression.
Antidepressant discontinuation syndrome, also called antidepressant withdrawal syndrome, is a condition that can occur following the interruption, reduction, or discontinuation of antidepressant medication.

Paroxetine

PaxilSeroxatparoxetine hydrochloride
Paroxetine was the first drug to be FDA approved for this disorder, it's efficacy is considered beneficial although not everyone respond favorably to the drug. This leaves out SSRIs such as paroxetine, sertraline and fluvoxamine CR as acceptable and tolerated treatment options for this disorder.
Paroxetine, sold under the brand names Paxil and Seroxat among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

Fluvoxamine

Luvox
Sertraline and fluvoxamine extended release were later approved for it too while escitalopram is used off label with acceptable efficacy. This leaves out SSRIs such as paroxetine, sertraline and fluvoxamine CR as acceptable and tolerated treatment options for this disorder.
Fluvoxamine, sold under the brand name Luvox among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class which is used primarily for the treatment of obsessive–compulsive disorder (OCD).

Citalopram

CelexaCipramilTalohexal
However, there isn't enough evidence to support citalopram for treating social phobia and fluoxetine was no better than placebo in clinical trials.
Citalopram, sold under the brand name Celexa among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

Sertraline

ZoloftLustralSertraline Hydrochloride
This leaves out SSRIs such as paroxetine, sertraline and fluvoxamine CR as acceptable and tolerated treatment options for this disorder.
Sertraline, sold under the trade name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

Venlafaxine

EffexorEffexor XRVenlafaxin
Fluoxetine and venlafaxine are used off label, with fluoxetine producing unsatisfactory mixed results and venlafaxine, while having a response rates of 78%, which is significantly higher than what paroxetine and sertraline achieved, but it did not address all the symptoms of ptsd like the two drugs did, which is in part due to the fact the venlafaxine is an SNRI, this class of drugs inhibit the reuptake of norepinephrine too, this could cause some anxiety in some patients.
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.

Anxiety disorder

anxiety disordersanxietynervous disorder
Antidepressants are medications used to treat major depressive disorder, some anxiety disorders, some chronic pain conditions, and to help manage some addictions.
Medications, such as antidepressants, benzodiazepines, or beta blockers, may improve symptoms.

Escitalopram

LexaproCipralexEcitalopram
Fluvoxamine, escitalopram and citalopram were not well tested in this disorder.
Escitalopram, sold under the brand names Cipralex and Lexapro among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

Fluoxetine

ProzacProzakSarafem
Paroxetine, sertraline, fluoxetine are FDA approved for panic disorder, although fluvoxamine, escitalopram and citalopram are considered effective for it. Antidepressants including amitriptyline, fluoxetine, duloxetine, milnacipran, moclobemide, and pirlindole are recommended by the European League Against Rheumatism (EULAR) for the treatment of fibromyalgia based on "limited evidence".
Fluoxetine, sold under the brand names Prozac and Sarafem among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

Obsessive–compulsive disorder

obsessive-compulsive disorderobsessive compulsive disorderOCD
SSRIs are a second-line treatment of adult obsessive–compulsive disorder (OCD) with mild functional impairment and as first-line treatment for those with moderate or severe impairment.
Treatment involves counseling, such as cognitive behavioral therapy (CBT), and sometimes antidepressants such as selective serotonin reuptake inhibitors (SSRIs) or clomipramine.

Lithium (medication)

lithiumlithium saltslithium salt
These include lithium and thyroid augmentation, dopamine agonists, sex steroids, NRIs, glucocorticoid-specific agents, or the newer anticonvulsants.
This includes the treatment of major depressive disorder that does not improve following the use of other antidepressants, and bipolar disorder.

Panic disorder

panicpanic disorderspanic disorde
Panic disorder is relatively treated well with medications compared with other disorders, several classes of antidepressants have shown efficacy for this disorder, however SSRIs and SNRIs are used first-line.
Medications used include antidepressants and occasionally benzodiazepines or beta blockers.

Desvenlafaxine

DesmethylvenlafaxinePristiqDes-venlafaxine
As of now, it is unclear if duloxetine and desvenlafaxine can provide benefits for social anxiety sufferers.
It is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.

Mirtazapine

RemeronmirtazepineAvanza
Mirtazapine is reported to have fewer sexual side-effects, most likely because it antagonizes 5-HT 2 and 5-HT 3 receptors and may, in some cases, reverse sexual dysfunction induced by SSRIs by the same mechanism.
Mirtazapine, sold under the brand name Remeron among others, is an antidepressant primarily used to treat depression.

Bipolar disorder

bipolarmanic depressionmanic depressive
Another possible problem with antidepressants is the chance of antidepressant-induced mania or hypomania in patients with or without a diagnosis of bipolar disorder.
In periods of mania, it is recommended that antidepressants be stopped.

Selective serotonin reuptake inhibitor

SSRIselective serotonin reuptake inhibitorsSSRIs
Bupropion, a weak NDRI and nicotinic antagonist, may be useful in treating reduced libido as a result of SSRI treatment. Selective serotonin reuptake inhibitors (SSRIs) are believed to increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption into the presynaptic cell, increasing the level of serotonin in the synaptic cleft available to bind to the postsynaptic receptor.
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders.

Binge eating disorder

Binge Eatingbinge-eating disorderBinge Eating Disorder (BED)
Similar recommendations apply to binge eating disorder.
Three other classes of medications are also used in the treatment of binge eating disorder: antidepressants, anticonvulsants, and anti-obesity medications.

Sexual dysfunction

sexual disorderssexualsexual problems
Common side-effects of antidepressants include dry mouth, weight gain, dizziness, headaches, and sexual dysfunction.
Individuals who take drugs to lower blood pressure or use antipsychotics, antidepressants, sedatives, narcotics, antacids or alcohol can have problems with sexual function and loss of libido.

Pirlindole

Antidepressants including amitriptyline, fluoxetine, duloxetine, milnacipran, moclobemide, and pirlindole are recommended by the European League Against Rheumatism (EULAR) for the treatment of fibromyalgia based on "limited evidence".
Pirlindole (Lifril, Pyrazidol) is a reversible inhibitor of monoamine oxidase A (RIMA) which was developed and is used in Russia as an antidepressant.

Serotonin

5-HTserotonergic5-hydroxytryptamine
The earliest and probably most widely accepted scientific theory of antidepressant action is the monoamine hypothesis (which can be traced back to the 1950s), which states that depression is due to an imbalance (most often a deficiency) of the monoamine neurotransmitters (namely serotonin, norepinephrine and dopamine). Selective serotonin reuptake inhibitors (SSRIs) are believed to increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption into the presynaptic cell, increasing the level of serotonin in the synaptic cleft available to bind to the postsynaptic receptor.
Several classes of antidepressants, such as the SSRIs and the SNRIs among others, interfere with the normal reabsorption of serotonin after it is done with the transmission of the signal, therefore augmenting the neurotransmitter levels in the synapses.

Anorgasmia

anorgasmicInhibited orgasmorgasm disorders
Sexual side-effects are also common with SSRIs, such as loss of sexual drive, failure to reach orgasm, and erectile dysfunction.
A common cause of situational anorgasmia, in both men and women, is the use of anti-depressants, particularly selective serotonin reuptake inhibitors (SSRIs).

Reuptake inhibitor

inhibitinhibitorinhibiting
Selective serotonin reuptake inhibitors (SSRIs) are believed to increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption into the presynaptic cell, increasing the level of serotonin in the synaptic cleft available to bind to the postsynaptic receptor.
Various drugs exert their psychological and physiological effects through reuptake inhibition, including many antidepressants and psychostimulants.

Serotonin syndrome

hyperserotonemiaserotonin toxicitycentral toxic serotonin reaction
Almost any medication involved with serotonin regulation has the potential to cause serotonin toxicity (also known as serotonin syndrome) – an excess of serotonin that can induce mania, restlessness, agitation, emotional lability, insomnia and confusion as its primary symptoms.

Vortioxetine

Trintellix
The term was coined in reference to the mechanism of action of the serotonergic antidepressant vortioxetine, which acts as a serotonin reuptake inhibitor (SRI), partial agonist of the 5-HT 1A receptor, and antagonist of the 5-HT 3 and 5-HT 7 receptors.
Effectiveness is viewed as similar to that of other antidepressants.

Trazodone

DesyrelOleptroTrialodine
They include trazodone and nefazodone.
Trazodone, sold under many brand names, is an antidepressant medication.