Antiemetic

antiemeticsanti-emeticanti-emeticsanti-nausea medicationnauseareduce nausea and vomitinganti vomitinganti-nauseaanti-nausea agentsanti-nausea drugs
An antiemetic is a drug that is effective against vomiting and nausea.wikipedia
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Nausea

nauseousvomitingfeeling of sickness
An antiemetic is a drug that is effective against vomiting and nausea.
Medications taken to prevent and treat nausea are called antiemetics.

5-HT3 antagonist

5-HT 3 antagonist5-HT 3 receptor antagonist5-HT 3 receptor antagonists
5-HT 3 receptor antagonists block serotonin receptors in the central nervous system and gastrointestinal tract. As such, they can be used to treat post-operative and cytotoxic drug nausea & vomiting. However, they can also cause constipation or diarrhea, dry mouth, and fatigue.
With the notable exceptions of alosetron and cilansetron, which are used in the treatment of irritable bowel syndrome, all 5-HT 3 antagonists are antiemetics, used in the prevention and treatment of nausea and vomiting.

Analgesic

analgesiaanalgesicspainkillers
Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer.
Patients starting morphine may experience nausea and vomiting (generally relieved by a short course of antiemetics such as phenergan).

Domperidone

[3H]domperidone
Domperidone (Motilium)
Domperidone, sold under the brand name Motilium among others, is a peripherally selective dopamine D 2 receptor antagonist that was developed by Janssen Pharmaceutica and is used as an antiemetic, gastroprokinetic agent, and galactagogue.

Dopamine antagonist

antidopaminergicantagonistdopamine antagonists
Dopamine antagonists act in the brain and are used to treat nausea and vomiting associated with neoplastic disease, radiation sickness, opioids, cytotoxic drugs and general anaesthetics. Side effects include muscle spasms and restlessness.
Several other dopamine antagonists are antiemetics used in the treatment of nausea and vomiting.

Granisetron

Kytril
Granisetron (Kytril, Sancuso) can be administered in tablet (Kytril), oral solution (Kytril), injection D(Kytril), or in a single transdermal patch to the upper arm (SANCUSO).
Granisetron is a serotonin 5-HT 3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy and Radiotherapy.

Medication

pharmaceuticalpharmaceuticalsdrug
An antiemetic is a drug that is effective against vomiting and nausea.
Drugs affecting the central nervous system include: Psychedelics, hypnotics, anaesthetics, antipsychotics, eugeroics, antidepressants (including tricyclic antidepressants, monoamine oxidase inhibitors, lithium salts, and selective serotonin reuptake inhibitors (SSRIs)), antiemetics, Anticonvulsants/antiepileptics, anxiolytics, barbiturates, movement disorder (e.g., Parkinson's disease) drugs, stimulants (including amphetamines), benzodiazepines, cyclopyrrolones, dopamine antagonists, antihistamines, cholinergics, anticholinergics, emetics, cannabinoids, and 5-HT (serotonin) antagonists.

Aprepitant

(see Summary of NK1RAs in Major Depression)emend
Aprepitant (Emend) is a commercially available NK1 Receptor antagonist
Aprepitant (brand name: Emend (the brand name used in all English-speaking countries)) is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA).

Tropisetron

Tropisetron (Setrovel, Navoban) can be administered in oral capsules or in injection form.
Tropisetron (INN) is a serotonin 5-HT 3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy, although it has been used experimentally as an analgesic in cases of fibromyalgia.

NK1 receptor antagonist

NK 1 receptor antagonistneurokinin-1 (NK 1 ) receptor antagonistneurokinin-1 antagonist
NK1 receptor antagonist
Neurokinin 1 (NK 1 ) antagonists (-pitants) are a novel class of medications that possesses unique antidepressant, anxiolytic, and antiemetic properties.

Droperidol

droperido
Droperidol, haloperidol, chlorpromazine, prochlorperazine. Some of these drugs are limited in their usefulness by their extra-pyramidal and sedative side-effects.
Droperidol (Inapsine, Droleptan, Dridol, Xomolix, Innovar [combination with fentanyl]) is an antidopaminergic drug used as an antiemetic (that is, to prevent or treat nausea) and as an antipsychotic.

Dronabinol

Marinolsynthetic pill form
Dronabinol (Marinol/Syndros) is a Schedule III drug in the U.S.
The International Nonproprietary Name Dronabinol, sold as trade names Marinol and Syndros, is an appetite stimulant, antiemetic, and sleep apnea reliever.

Medical cannabis

medical marijuanamedicinalmedical
Cannabis, also known as medical marijuana in the United States, is a Schedule I drug.
Low quality evidence suggests its use for reducing nausea during chemotherapy, improving appetite in HIV/AIDS, improving sleep, and improving tics in Tourette syndrome.

Meclizine

meclozine
Meclizine (Bonine, Antivert)
Meclizine (INN, or meclozine) is an antihistamine of the diphenylmethylpiperazine group considered to be an antiemetic.

Nabilone

Cesamet
Some synthetic cannabinoids such as Nabilone (Cesamet) or the JWH series.
Nabilone, sold under the brand name Cesamet among others, is a synthetic cannabinoid with therapeutic use as an antiemetic and as an adjunct analgesic for neuropathic pain.

Rolapitant

Rolapitant (Varubi) another recently approved drug from this class
Rolapitant is used in combination with other antiemetic (anti-vomiting) agents in adults for the prevention of delayed nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy, including, but not limited to, highly emetogenic chemotherapy.

Diphenhydramine

diphenhydramine hydrochlorideNytolAllergan
Diphenhydramine (Benadryl)
Diphenhydramine also has antiemetic properties, which make it useful in treating the nausea that occurs in vertigo and motion sickness.

Prochlorperazine

Droperidol, haloperidol, chlorpromazine, prochlorperazine. Some of these drugs are limited in their usefulness by their extra-pyramidal and sedative side-effects.
Prochlorperazine is a dopamine (D 2 ) receptor antagonist that belongs to the phenothiazine class of antipsychotic agents that are used for the antiemetic treatment of nausea and vertigo.

Serotonin

5-HTserotonergic5-hydroxytryptamine
5-HT 3 receptor antagonists block serotonin receptors in the central nervous system and gastrointestinal tract. As such, they can be used to treat post-operative and cytotoxic drug nausea & vomiting. However, they can also cause constipation or diarrhea, dry mouth, and fatigue.
Several classes of drugs target the 5-HT system, including some antidepressants, antipsychotics, anxiolytics, antiemetics, and antimigraine drugs, as well as the psychedelic drugs and empathogens.

Trimethobenzamide

Trimethobenzamide is thought to work on the CTZ
Trimethobenzamide (trade names Tebamide, Tigan) is an antiemetic used to prevent nausea and vomiting.

Synthetic cannabinoids

synthetic cannabinoidsynthetic cannabisSpice
Some synthetic cannabinoids such as Nabilone (Cesamet) or the JWH series.
Nabilone, a first generation synthetic THC analog, has been used as an antiemetic to combat vomiting and nausea, since 1981.

Dolasetron

Dolasetron (Anzemet) can be administered in tablet form or in an injection.
It does not have much antiemetic effect when symptoms are due to motion sickness.

Alizapride

Alizapride
Alizapride (Litican, Plitican, Superan, Vergentan) is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.

Chemotherapy

chemotherapeuticantineoplasticantineoplastic agent
Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer.
These side-effects can frequently be reduced or eliminated with antiemetic drugs.

Hyperemesis gravidarum

hyperemesissevere nausea and vomiting
Antiemetics, though previously thought to cause birth defects, have been proven safe for use by pregnant women in the treatment of morning sickness and the more serious hyperemesis gravidarum.
If conservative dietary measures fail, more extensive treatment such as the use of antiemetic medications and intravenous rehydration may be required.