A report on Malaria, Antimalarial medication, Plasmodium falciparum and Artemisia annua
Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women.- Antimalarial medication
Plasmodium falciparum is a unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that causes malaria in humans.- Plasmodium falciparum
An extract of A. annua, called artemisinin (or artesunate), is a medication used to treat malaria.- Artemisia annua
Practice in treating cases of malaria is most often based on the concept of combination therapy (e.g., using agents such as artemether and lumefantrine against chloroquine-resistant Plasmodium falciparum infection), since this offers advantages including reduced risk of treatment failure, reduced risk of developed resistance, as well as the possibility of reduced side-effects.- Antimalarial medication
Most deaths are caused by P. falciparum, whereas P. vivax, P. ovale, and P. malariae generally cause a milder form of malaria.- Malaria
The recommended treatment for malaria is a combination of antimalarial medications that includes artemisinin.- Malaria
In 1971, scientists demonstrated the plant extracts had antimalarial activity in primate models, and in 1972, the active ingredient, artemisinin (formerly referred to as arteannuin), was isolated and its chemical structure described.- Artemisia annua
Malaria is caused by apicomplexans, primarily Plasmodium falciparum, which largely reside in red blood cells and contain iron-rich heme-groups (in the form of hemozoin).- Artemisia annua
It is derived from the plant Artemisia annua, with the first documentation as a successful therapeutic agent in the treatment of malaria is in 340 AD by Ge Hong in his book Zhou Hou Bei Ji Fang (A Handbook of Prescriptions for Emergencies).- Antimalarial medication
Tu Youyou discovered artemisinin in the 1970s from sweet wormwood (Artemisia annua).- Plasmodium falciparum
According to WHO guidelines 2010, artemisinin-based combination therapies (ACTs) are the recommended first-line antimalarial treatments for uncomplicated malaria caused by P. falciparum.- Plasmodium falciparum
The medicinal value of Artemisia annua has been used by Chinese herbalists in traditional Chinese medicines for 2,000 years.- Malaria
1 related topic with Alpha
Artemisinin and its semisynthetic derivatives are a group of drugs used in the treatment of malaria due to Plasmodium falciparum.
Artemisinin-based combination therapies (ACTs) are now standard treatment worldwide for P. falciparum malaria as well as malaria due to other species of Plasmodium.
Artemisinin is extracted from the plant Artemisia annua, sweet wormwood, a herb employed in Chinese traditional medicine.