A report on Artemisinin and Artemisia annua
An extract of A. annua, called artemisinin (or artesunate), is a medication used to treat malaria.
- Artemisia annuaArtemisinin is extracted from the plant Artemisia annua, sweet wormwood, a herb employed in Chinese traditional medicine.
- Artemisinin8 related topics with Alpha
Antimalarial medication
4 linksAntimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women.
Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women.
Incidence and distribution of the disease ("malaria burden") is expected to remain high, globally, for many years to come; moreover, known antimalarial drugs have repeatedly been observed to elicit resistance in the malaria parasite—including for combination therapies featuring artemisinin, a drug of last resort, where resistance has now been observed in Southeast Asia.
It is derived from the plant Artemisia annua, with the first documentation as a successful therapeutic agent in the treatment of malaria is in 340 AD by Ge Hong in his book Zhou Hou Bei Ji Fang (A Handbook of Prescriptions for Emergencies).
Tu Youyou
3 linksChinese pharmaceutical chemist and malariologist.
Chinese pharmaceutical chemist and malariologist.
She discovered artemisinin (also known as qīnghāosù, 青蒿素) and dihydroartemisinin, used to treat malaria, a breakthrough in twentieth-century tropical medicine, saving millions of lives in South China, Southeast Asia, Africa, and South America.
One compound was effective, sweet wormwood (Artemisia annua), which was used for "intermittent fevers," a hallmark of malaria.
Malaria
3 linksMosquito-borne infectious disease that affects humans and other animals.
Mosquito-borne infectious disease that affects humans and other animals.
The recommended treatment for malaria is a combination of antimalarial medications that includes artemisinin.
The medicinal value of Artemisia annua has been used by Chinese herbalists in traditional Chinese medicines for 2,000 years.
Artesunate
2 linksMedication used to treat malaria.
Medication used to treat malaria.
It is in the artemisinin class of medication.
It is in the class of medications known as artemisinins, which are derivatives from "qinghao," or sweet wormwood plant (Artemisia annua).
Artemether
2 linksMedication used for the treatment of malaria.
Medication used for the treatment of malaria.
It is in the artemisinin class of medication.
Artemether is a methyl ether derivative of artemisinin, which is a peroxide-containing lactone isolated from the antimalarial plant Artemisia annua.
Plasmodium falciparum
2 linksUnicellular protozoan parasite of humans, and the deadliest species of Plasmodium that causes malaria in humans.
Unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that causes malaria in humans.
Tu Youyou discovered artemisinin in the 1970s from sweet wormwood (Artemisia annua).
Project 523
1 linksCode name for a 1967 secret military project of the People's Republic of China to find antimalarial medications.
Code name for a 1967 secret military project of the People's Republic of China to find antimalarial medications.
The one for investigating traditional Chinese medicine discovered and led to the development of a class of new antimalarial drugs called artemisinins.
Another early candidate was huanghuahao (sweet wormwood or Artemisia annua).
Traditional Chinese medicine
1 linksAlternative medical practice drawn from traditional medicine in China.
Alternative medical practice drawn from traditional medicine in China.
There had been success in the 1970s, however, with the development of the antimalarial drug artemisinin, which is a processed extract of Artemisia annua, a herb traditionally used as a fever treatment.