A report on Artemisinin
Artemisinin and its semisynthetic derivatives are a group of drugs used in the treatment of malaria due to Plasmodium falciparum.
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Artemisia annua
8 linksCommon type of wormwood native to temperate Asia, but naturalized in many countries including scattered parts of North America.
Common type of wormwood native to temperate Asia, but naturalized in many countries including scattered parts of North America.
An extract of A. annua, called artemisinin (or artesunate), is a medication used to treat malaria.
Malaria
7 linksMosquito-borne infectious disease that affects humans and other animals.
Mosquito-borne infectious disease that affects humans and other animals.
The recommended treatment for malaria is a combination of antimalarial medications that includes artemisinin.
Antimalarial medication
6 linksAntimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women.
Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women.
Incidence and distribution of the disease ("malaria burden") is expected to remain high, globally, for many years to come; moreover, known antimalarial drugs have repeatedly been observed to elicit resistance in the malaria parasite—including for combination therapies featuring artemisinin, a drug of last resort, where resistance has now been observed in Southeast Asia.
Tu Youyou
4 linksChinese pharmaceutical chemist and malariologist.
Chinese pharmaceutical chemist and malariologist.
She discovered artemisinin (also known as qīnghāosù, 青蒿素) and dihydroartemisinin, used to treat malaria, a breakthrough in twentieth-century tropical medicine, saving millions of lives in South China, Southeast Asia, Africa, and South America.
Artesunate
5 linksMedication used to treat malaria.
Medication used to treat malaria.
It is in the artemisinin class of medication.
Plasmodium falciparum
6 linksUnicellular protozoan parasite of humans, and the deadliest species of Plasmodium that causes malaria in humans.
Unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that causes malaria in humans.
Tu Youyou discovered artemisinin in the 1970s from sweet wormwood (Artemisia annua).
Artemether
4 linksMedication used for the treatment of malaria.
Medication used for the treatment of malaria.
It is in the artemisinin class of medication.
Quinine
3 linksMedication used to treat malaria and babesiosis.
Medication used to treat malaria and babesiosis.
They recommend that it be used only when artemisinins are not available.
Dihydroartemisinin
2 linksDrug used to treat malaria.
Drug used to treat malaria.
Dihydroartemisinin is the active metabolite of all artemisinin compounds (artemisinin, artesunate, artemether, etc.) and is also available as a drug in itself.
Plasmodium
3 linksGenus of unicellular eukaryotes that are obligate parasites of vertebrates and insects.
Genus of unicellular eukaryotes that are obligate parasites of vertebrates and insects.
Resistance to quinine spurred the development of a broad array of antimalarial medications through the 20th century including chloroquine, proguanil, atovaquone, sulfadoxine/pyrimethamine, mefloquine, and artemisinin.