Esophageal cancer is cancer arising from the esophagus—the food pipe that runs between the throat and the stomach.- Esophageal cancer
Barrett's esophagus is a condition in which there is an abnormal (metaplastic) change in the mucosal cells lining the lower portion of the esophagus, from stratified squamous epithelium to simple columnar epithelium with interspersed goblet cells that are normally present only in the small intestine and large intestine.- Barrett's esophagus
This change is considered to be a premalignant condition because it is associated with a high incidence of further transition to esophageal adenocarcinoma, an often-deadly cancer.- Barrett's esophagus
Heartburn is usually due to regurgitation of gastric acid (gastric reflux) into the esophagus.- Heartburn
Adenocarcinoma arises from glandular cells present in the lower third of the esophagus, often where they have already transformed to intestinal cell type (a condition known as Barrett's esophagus).- Esophageal cancer
The esophagus may be affected by gastric reflux, cancer, prominent dilated blood vessels called varices that can bleed heavily, tears, constrictions, and disorders of motility.- Esophagus
frequent and longstanding heartburn- Barrett's esophagus
Pain behind the breastbone or in the region around the stomach often feels like heartburn.- Esophageal cancer
Esophageal cancers- Heartburn
Dysfunction of the gastroesophageal sphincter causes gastroesophageal reflux, which causes heartburn, and, if it happens often enough, can lead to gastroesophageal reflux disease, with damage of the esophageal mucosa.- Esophagus
Endoscopy looking for erosive changes of the esophagus consistent with prolonged acid exposure (e.g. - Barrett's esophagus)- Heartburn
Normally, the cardia of the stomach is immediately distal to the z-line and the z-line coincides with the upper limit of the gastric folds of the cardia; however, when the anatomy of the mucosa is distorted in Barrett's esophagus the true gastro-eshophageal junction can be identified by the upper limit of the gastric folds rather than the mucosal transition.- Esophagus
1 related topic with Alpha
Gastroesophageal reflux disease (GERD) or gastro-oesophageal reflux disease (GORD) is a chronic condition in which stomach contents and acid rise up into the esophagus, resulting in symptoms and/or complications.
Symptoms include the taste of acid in the back of the mouth, heartburn, bad breath, chest pain, regurgitation, breathing problems, and wearing away of the teeth.
Complications include esophagitis, esophageal stricture, and Barrett's esophagus.
Esophageal adenocarcinoma – a form of cancer