An illustration of breast cancer
Nolvadex (tamoxifen) 20 mg tablets.
A coronal CT scan showing a malignant mesothelioma
Legend: → tumor ←, ✱ central pleural effusion, 1 & 3 lungs, 2 spine, 4 ribs, 5 aorta, 6 spleen, 7 & 8 kidneys, 9 liver
The location and development of endometrial cancer.
Breast cancer showing an inverted nipple, lump, and skin dimpling
Crystallographic structure of afimoxifene (carbon = white, oxygen = red, nitrogen = blue) complexed with ligand binding domain of estrogen receptor alpha (ERα) (cyan ribbon).
Symptoms of cancer metastasis depend on the location of the tumor.
The location and development of endometrial cancer.
Early signs of possible breast cancer
The GHS Hazard pictogram for carcinogenic substances
The autosomal dominant inheritance pattern seen in Lynch syndrome
Tumor in the breast visualized by Breast-Computertomography (Breast-CT)
Share of cancer deaths attributed to tobacco in 2016.
Immunohistochemistry of endometrial endometrioid carcinoma with wild-type pattern of p53 expression, with variable proportion of tumor cell nuclei staining with variable intensity.
All types of alcoholic beverages, including beer, wine, or liquor, cause breast cancer.
The incidence of lung cancer is highly correlated with smoking.
Vaginal ultrasonography with an endometrial fluid accumulation (darker area) in a postmenopausal uterus, a finding that is highly suspicious for endometrial cancer
Ducts and lobules, the main locations of breast cancers
Cancers are caused by a series of mutations. Each mutation alters the behavior of the cell somewhat.
Polypoidal endometrial carcinoma
Overview of signal transduction pathways involved in programmed cell death. Mutations leading to loss of this ability can lead to cancer formation.
The central role of DNA damage and epigenetic defects in DNA repair genes in carcinogenesis
Relative incidences of endometrial carcinomas by histopathology.
Histopathologic types of breast cancer, with relative incidences and prognoses
Chest X-ray showing lung cancer in the left lung
Endometrioid endometrial adenocarcinoma—very high magnification—H&E stain
A mobile breast cancer screening unit in New Zealand
Three measures of global cancer mortality from 1990 to 2017
A keyhole hysterectomy, one possible surgery to treat endometrial cancer
Chest after right breast mastectomy
Engraving with two views of a Dutch woman who had a tumor removed from her neck in 1689
alt=A diagram of stage IA and IB endometrial cancer|Stage IA and IB endometrial cancer
Internal radiotherapy for breast cancer
University of Florida Cancer Hospital
alt=A diagram of stage II endometrial cancer|Stage II endometrial cancer
Breasts after double mastectomy followed by nipple-sparing reconstruction with implants
CancerTreeMammal
alt=A diagram of stage III endometrial cancer|Stage III endometrial cancer
An extreme example of an advanced recurrent breast cancer with an ulcerating axillary mass
An invasive ductal carcinoma of the breast (pale area at the center) surrounded by spikes of whitish scar tissue and yellow fatty tissue
alt=A diagram of stage IV endometrial cancer|Stage IV endometrial cancer
Breast cancer surgery in 18th century
An invasive colorectal carcinoma (top center) in a colectomy specimen
Radical mastectomy, Halsted's surgical papers
A squamous-cell carcinoma (the whitish tumor) near the bronchi in a lung specimen
The pink ribbon is a symbol to show support for breast cancer awareness.
A large invasive ductal carcinoma in a mastectomy specimen
MRI showing breast cancer
Excised human breast tissue, showing an irregular, dense, white stellate area of cancer 2cm in diameter, within yellow fatty tissue
High-grade invasive ductal carcinoma, with minimal tubule formation, marked pleomorphism, and prominent mitoses, 40x field
Micrograph showing a lymph node invaded by ductal breast carcinoma, with an extension of the tumor beyond the lymph node
Neuropilin-2 expression in normal breast and breast carcinoma tissue
F-18 FDG PET/CT: A breast cancer metastasis to the right scapula
Needle breast biopsy
Elastography shows stiff cancer tissue on ultrasound imaging.
Ultrasound image shows irregularly shaped mass of breast cancer.
Infiltrating (invasive) breast carcinoma
Mammograms showing a normal breast (left) and a breast with cancer (right)
Stage T1 breast cancer
Stage T2 breast cancer
Stage T3 breast cancer
Metastatic or stage 4 breast cancer
Stage 1A breast cancer
Stage 1B breast cancer
Stage 2A breast cancer
Stage 2A breast cancer
Stage 2B breast cancer
Stage 2B breast cancer
Stage 2B breast cancer
Stage 3A breast cancer
Stage 3A breast cancer
Stage 3A breast cancer
Stage 3B breast cancer
Stage 3B breast cancer
Stage 4 breast cancer

Breast cancer is cancer that develops from breast tissue.

- Breast cancer

Tamoxifen, sold under the brand name Nolvadex among others, is a selective estrogen receptor modulator used to prevent breast cancer in women and treat breast cancer in women and men.

- Tamoxifen

Endometrial cancer is a cancer that arises from the endometrium (the lining of the uterus or womb).

- Endometrial cancer

It is also being studied for other types of cancer.

- Tamoxifen

The medications tamoxifen or raloxifene may be used in an effort to prevent breast cancer in those who are at high risk of developing it.

- Breast cancer

Tamoxifen increases the risk of postmenopausal bleeding, endometrial polyps, hyperplasia, and endometrial cancer; using tamoxifen with an intrauterine system releasing levonorgestrel might increase vaginal bleeding after 1 to 2 years, but reduces somewhat endometrial polyps and hyperplasia, but not necessarily endometrial cancer.

- Tamoxifen

The benefits of screening for breast cancer are controversial.

- Cancer

Risk factors for endometrial cancer include obesity, insulin resistance and diabetes mellitus, breast cancer, use of tamoxifen, never having had a child, late menopause, high levels of estrogen, and increasing age.

- Endometrial cancer

The selective estrogen receptor modulators reduce the risk of breast cancer but increase the risk of thromboembolism and endometrial cancer.

- Breast cancer

But a minority of cancer types rely on oxidative phosphorylation as the primary energy source, including lymphoma, leukemia, and endometrial cancer.

- Cancer

Daily use of tamoxifen or raloxifene reduce the risk of breast cancer in high-risk women.

- Cancer
An illustration of breast cancer

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