Breast cancer

An illustration of breast cancer
Breast cancer showing an inverted nipple, lump, and skin dimpling
Early signs of possible breast cancer
Tumor in the breast visualized by Breast-Computertomography (Breast-CT)
All types of alcoholic beverages, including beer, wine, or liquor, cause breast cancer.
Ducts and lobules, the main locations of breast cancers
Overview of signal transduction pathways involved in programmed cell death. Mutations leading to loss of this ability can lead to cancer formation.
Histopathologic types of breast cancer, with relative incidences and prognoses
A mobile breast cancer screening unit in New Zealand
Chest after right breast mastectomy
Internal radiotherapy for breast cancer
Breasts after double mastectomy followed by nipple-sparing reconstruction with implants
An extreme example of an advanced recurrent breast cancer with an ulcerating axillary mass
Breast cancer surgery in 18th century
Radical mastectomy, Halsted's surgical papers
The pink ribbon is a symbol to show support for breast cancer awareness.
MRI showing breast cancer
Excised human breast tissue, showing an irregular, dense, white stellate area of cancer 2cm in diameter, within yellow fatty tissue
High-grade invasive ductal carcinoma, with minimal tubule formation, marked pleomorphism, and prominent mitoses, 40x field
Micrograph showing a lymph node invaded by ductal breast carcinoma, with an extension of the tumor beyond the lymph node
Neuropilin-2 expression in normal breast and breast carcinoma tissue
F-18 FDG PET/CT: A breast cancer metastasis to the right scapula
Needle breast biopsy
Elastography shows stiff cancer tissue on ultrasound imaging.
Ultrasound image shows irregularly shaped mass of breast cancer.
Infiltrating (invasive) breast carcinoma
Mammograms showing a normal breast (left) and a breast with cancer (right)
Stage T1 breast cancer
Stage T2 breast cancer
Stage T3 breast cancer
Metastatic or stage 4 breast cancer
Stage 1A breast cancer
Stage 1B breast cancer
Stage 2A breast cancer
Stage 2A breast cancer
Stage 2B breast cancer
Stage 2B breast cancer
Stage 2B breast cancer
Stage 3A breast cancer
Stage 3A breast cancer
Stage 3A breast cancer
Stage 3B breast cancer
Stage 3B breast cancer
Stage 4 breast cancer

Cancer that develops from breast tissue.

- Breast cancer
An illustration of breast cancer

103 related topics

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A package of birth control pills

Progestogen-only pill

Progestogen-only pills or progestin-only pills (POP) are contraceptive pills that contain only synthetic progestogens (progestins) and do not contain estrogen.

Progestogen-only pills or progestin-only pills (POP) are contraceptive pills that contain only synthetic progestogens (progestins) and do not contain estrogen.

A package of birth control pills

Epidemiological evidence on POPs and breast cancer risk is based on much smaller populations of users and so is less conclusive than that for COCPs.

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Pink ribbon

International symbol of breast cancer awareness.

International symbol of breast cancer awareness.

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100 women who survived breast cancer carry a pink ribbon and create the fight breast cancer logo.

Pink ribbons, and the color pink in general, identify the wearer or promoter with the breast cancer brand and express moral support for women with breast cancer.

Lymphadenectomy

Surgical removal of one or more groups of lymph nodes.

Surgical removal of one or more groups of lymph nodes.

This is particularly true of melanoma, head and neck cancer, differentiated thyroid cancer, breast cancer, lung cancer, gastric cancer and colorectal cancer.

Femara 2.5 mg oral tablet

Letrozole

Femara 2.5 mg oral tablet

Letrozole, sold under the brand name Femara ) among others, is an aromatase inhibitor which is used in the treatment of hormonally-responsive breast cancer after surgery.

Patients and their diseases are profiled in order to identify the most effective treatment for their specific case.

Targeted therapy

One of the major modalities of medical treatment for cancer, others being hormonal therapy and cytotoxic chemotherapy.

One of the major modalities of medical treatment for cancer, others being hormonal therapy and cytotoxic chemotherapy.

Patients and their diseases are profiled in order to identify the most effective treatment for their specific case.
Mechanism of imatinib

There are targeted therapies for lung cancer, colorectal cancer, head and neck cancer, breast cancer, multiple myeloma, lymphoma, prostate cancer, melanoma and other cancers.

Image illustrating sentinel lymph nodes. The axillary lymph nodes drain 75% of the lymph from the breasts((uncited)) and so may be the first lymph nodes affected in breast cancer.

Sentinel lymph node

Hypothetical first lymph node or group of nodes draining a cancer.

Hypothetical first lymph node or group of nodes draining a cancer.

Image illustrating sentinel lymph nodes. The axillary lymph nodes drain 75% of the lymph from the breasts((uncited)) and so may be the first lymph nodes affected in breast cancer.
A blue stained sentinel lymph node in the axilla.
A micrograph showing an adenocarcinoma of the breast (dark pink) in a lymph node (purple) and extending into the surrounding fat (white, chicken-wire appearance). H&E stain.

Its main uses are in breast cancer and malignant melanoma surgery, although it has been used in other tumor types (colon cancer) with a degree of success.

Symptoms of menopause

Hormone replacement therapy

Form of hormone therapy used to treat symptoms associated with female menopause.

Form of hormone therapy used to treat symptoms associated with female menopause.

Symptoms of menopause
The risks of coronary heart disease with HRT vary depending on age and time since menopause.
Clot in the greater saphenous vein; oral estrogen is associated with increased risk of venous blood clots due to increased liver formation of vitamin K-dependent clotting factors.
Endometrial cancer can be associated with HRT, particularly in those not taking a progestogen.
Atrophy of vaginal mucosa that occurs with menopause.
An intrauterine device can be used to receive HRT.

Studies regarding the association of breast cancer with hormone replacement are inconsistent and vary with type of replacement and time since menopause.

Schematic representation of trastuzumab emtansine. The maytansine skeleton is shown in black at left. The thioether group that makes mertansine is shown in red. The linker group that makes emtansine is shown in blue at right, bound to the amino group (HN–) of a lysine residue in the trastuzumab molecule (–mab).

Trastuzumab emtansine

Antibody-drug conjugate consisting of the humanized monoclonal antibody trastuzumab covalently linked to the cytotoxic agent DM1.

Antibody-drug conjugate consisting of the humanized monoclonal antibody trastuzumab covalently linked to the cytotoxic agent DM1.

Schematic representation of trastuzumab emtansine. The maytansine skeleton is shown in black at left. The thioether group that makes mertansine is shown in red. The linker group that makes emtansine is shown in blue at right, bound to the amino group (HN–) of a lysine residue in the trastuzumab molecule (–mab).

In the EMILIA clinical trial of women with advanced HER2 positive breast cancer who were already resistant to trastuzumab alone, it improved median overall survival by 5.8 months (30.9 months vs. 25.1 months) compared to the combination of lapatinib and capecitabine.

Aspirin

Medication used to reduce pain, fever, or inflammation.

Medication used to reduce pain, fever, or inflammation.

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1923 advertisement
Old package. "Export from Germany is prohibited"

It may also slightly reduce the risk of endometrial cancer, breast cancer, and prostate cancer.

Cyclophosphamide IV drip

Cyclophosphamide

Medication used as chemotherapy and to suppress the immune system.

Medication used as chemotherapy and to suppress the immune system.

Cyclophosphamide IV drip

As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma.