A report on Cannabis (drug) and Tetrahydrocannabinol

Close-up of flowering cannabis plant
Main short-term physical effects of cannabis
A joint prior to rolling, with a paper handmade filter on the left
Addiction experts in psychiatry, chemistry, pharmacology, forensic science, epidemiology, and the police and legal services engaged in delphic analysis regarding 20 popular recreational drugs. Cannabis was ranked 11th in dependence, 17th in physical harm, and 10th in social harm.
Types of cannabis
A macro cannabis bud
Present-day map of the Jirzankal Cemetery, site of the earliest evidence of cannabis smoking
Cannabis sativa from Vienna Dioscurides, c. 512 CE
Anti-Cannabis propaganda from 1935
Cannabis indica fluid extract, American Druggists Syndicate (pre-1937)
Process of making bhang in a Sikh village in Punjab, India. On the Hindu and Sikh festival of colors called Holi, it is a customary addition to some intoxicating drinks.
countries that have legalized medical use of cannabis
Example of a container and the recreational cannabis purchase in Canada.
Woman selling cannabis and bhang in Guwahati, Assam, India
Dried flower buds (marijuana)
A gram of kief
Hashish
Hash oil
Infusion (dairy butter)

Although the chemical formula for THC (C21H30O2) describes multiple isomers, the term THC usually refers to the Delta-9-THC isomer with chemical name (−)-trans-Δ9-tetrahydrocannabinol. Like most pharmacologically active secondary metabolites of plants, THC is a lipid found in cannabis, assumed to be involved in the plant's evolutionary adaptation, putatively against insect predation, ultraviolet light, and environmental stress.

- Tetrahydrocannabinol

Tetrahydrocannabinol (THC) is the main psychoactive component of cannabis, which is one of the 483 known compounds in the plant, including at least 65 other cannabinoids, including cannabidiol (CBD).

- Cannabis (drug)
Close-up of flowering cannabis plant

4 related topics with Alpha

Overall
The bracts surrounding a cluster of Cannabis sativa flowers are coated with cannabinoid-laden trichomes

Cannabinoid

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The bracts surrounding a cluster of Cannabis sativa flowers are coated with cannabinoid-laden trichomes
Cannabis indica plant
Anandamide, an endogenous ligand of CB1 and CB2

Cannabinoids are compounds found in the cannabis plant or synthetic compounds that can interact with the endocannabinoid system. The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (Delta-9-THC), the primary intoxicating compound in cannabis.

Cnr1 is widely expressed in all major regions of the postnatal day 14 mouse brain, but is conspicuously absent in much of the thalamus.

Cannabinoid receptor type 1

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G protein-coupled cannabinoid receptor that in humans is encoded by the CNR1 gene.

G protein-coupled cannabinoid receptor that in humans is encoded by the CNR1 gene.

Cnr1 is widely expressed in all major regions of the postnatal day 14 mouse brain, but is conspicuously absent in much of the thalamus.

It is activated by: endocannabinoids, a group of retrograde neurotransmitters that include anandamide and 2-arachidonoylglycerol (2-AG); plant phytocannabinoids, such as the compound THC which is an active ingredient of the psychoactive drug cannabis; and, synthetic analogs of THC.

NMR solution structure of a peptide mimetic of the fourth cytoplasmic loop of the CB1 cannabinoid receptor based on the coordinates.

Cannabinoid receptor

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Involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory.

Involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory.

NMR solution structure of a peptide mimetic of the fourth cytoplasmic loop of the CB1 cannabinoid receptor based on the coordinates.
CB1 and CB2 structures

Cannabinoid receptors are activated by three major groups of ligands: endocannabinoids, produced by the mammillary body; plant cannabinoids (such as Tetrahydrocannabinol, produced by the cannabis plant); and synthetic cannabinoids (such as HU-210).

Cannabinoid receptors are activated by cannabinoids, generated naturally inside the body (endocannabinoids) or introduced into the body as cannabis or a related synthetic compound.

Cannabis

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Genus of flowering plants in the family Cannabaceae.

Genus of flowering plants in the family Cannabaceae.

Cannabis growing as weeds at the foot of Dhaulagiri, Nepal.
A thicket of wild cannabis in Islamabad, Pakistan.
Cannabis female flower with visible trichomes
Male Cannabis flower buds
Underside of Cannabis sativa leaf, showing diagnostic venation
Top of Cannabis plant in vegetative growth stage
Relative size of varieties of Cannabis
Cannabis ruderalis
Comparison of physical harm and dependence regarding various drugs
A dried bud, typical of what is sold for recreational use
Commercial cannabis extract
Cannabis sativa stem longitudinal section
Cannabis Museum in Amsterdam
Cannabis leaf pictured in the coat of arms of Kanepi Parish
A male hemp plant
Dense raceme of female flowers typical of drug-type varieties of Cannabis
Root system side view
Root system top view
Micrograph C. sativa (left), C. indica (right)

Cannabis has long been used for hemp fibre, hemp seeds and their oils, hemp leaves for use as vegetables and as juice, medicinal purposes, and as a recreational drug.

To satisfy the UN Narcotics Convention, some cannabis strains have been bred to produce minimal levels of tetrahydrocannabinol (THC), the principal psychoactive constituent.