Pitcher Jim McCormick started five of the seven games for Chicago in the 1885 World Series between the two teams, going 3–2.
The 1876 White Stockings won the NL championship.
1919 "Black Sox" team photo
Mark McGwire hitting a home run at Busch Stadium.
Charles Comiskey, shown here circa 1910, guided the Browns to four American Association titles.
The 1906 Cubs won a record 116 of 154 games. They then won back-to-back World Series titles in 1907–08.
Ed Walsh holds the record for lowest career earned run average (ERA), 1.82
Wrigley Field and the Cubs play host to the rival St. Louis Cardinals 9-10 games a season
Rogers Hornsby won two Triple Crowns as a Cardinal.
1913 Chicago Cubs
Al López, manager of the "Go-Go Sox"
Dusty Baker, manager of the Chicago Cubs (2003–2006)
Stan Musial retired owning numerous National League and team batting records.
Hall of Famer Hack Wilson
Harold Baines at the plate in 1986
Rogers Hornsby played for the St. Louis Cardinals 1915–1926 & 1933 and with the Chicago Cubs 1929–1932. Hornsby owns the single season record for both franchises in hits and runs.
Bob Gibson, the most decorated pitcher in team history, won two Cy Young Awards.
Club logo (1927–1936)
Frank Thomas in 1997
Pitcher Chris Carpenter, essential in two World Series titles, won 10 playoff games with a 3.00 postseason ERA.
Cubs logo (1941–1945)
The White Sox celebrate after winning a tie-breaker game against the Minnesota Twins for a spot in the 2008 playoffs
Albert Pujols is one of the most accomplished players in Cardinals' history.
A sports-related curse that was supposedly placed on the Chicago Cubs by Billy Goat Tavern owner William Sianis during Game 4 of the 1945 World Series.
View from the upper deck of U.S. Cellular Field in 2006
Sportsman's Park during the 1946 World Series
Ernie Banks ("Mr. Cub")
Batting practice at Comiskey Park, 1986
Busch Memorial Stadium, home stadium from 1966 to 2005
Ryne Sandberg set numerous league and club records in his career and was elected to the Hall of Fame in 2005.
The 1912–1917, 1919–1929, 1931, and 1936–1938 Chicago White Sox logo
St. Louis logo (1900–1919)
Andre Dawson, 5× All-Star and 1987 NL MVP during tenure in Chicago
Uniform design from 1971–1975
St. Louis mascot Fredbird, 2013
Sammy Sosa was the captain of the Chicago Cubs during his tenure with the team.
Alternate logo, used on the road uniform (1991–2010) and on the black alternate uniform (1993–present).
Red Schoendienst (1965–76, 1980, 1990)
Kerry Wood, along with Mark Prior, led the Cubs' rotation in 2003.
Eddie Murphy, John "Shano" Collins, Joe Jackson, Happy Felsch, and Nemo Leibold in their dugout during the 1917 World Series
Tony La Russa (1996–2011)
Dempster emerged in 2004 and became the Cubs' regular closer.
Luis Aparicio (1956–62, 1968–70)
Joe Medwick's Triple Crown in 1937 is the last in the history of the National League
Alfonso Soriano signed with the club in 2007.
Luke Appling (1930–43, 1945–50)
Lou Brock
Carlos Zambrano warming up before a game
Carlton Fisk (1981–1993)
Dizzy Dean
Starlin Castro during his 2010 rookie season
Nellie Fox (1950–1963)
Curt Flood
One of two Cubs building blocks, Anthony Rizzo, swinging in the box
Shoeless Joe Jackson (1915–1920)
Enos Slaughter
The Cubs celebrate after winning the 2016 World Series.
Ted Lyons (1923–1942, 1946)
Ozzie Smith
2016 Champions visit the White House in June 2017.
Minnie Miñoso (1951–57, 1960–61, 1964, 1976, 1980)
Bruce Sutter
Clark (left) with the Oriole Bird
Bill Veeck, White Sox owner (1959–61, 1975–80) who revolutionized baseball by introducing many innovations in promotion
Harry Caray
Ron Santo
Southpaw
Billy Williams
Fielder Jones of the White Sox hits the ball against Cubs at West Side Grounds, 1905
Ferguson Jenkins
Elson in the 1940s
Kiki Cuyler
Harrelson in the broadcast booth in 2007
Mordecai "Three Finger" Brown
Harry Caray

The Cardinals–Cubs rivalry, also called the Route 66 rivalry and The I-55 rivalry, refers to the rivalry between the St. Louis Cardinals and Chicago Cubs of the National League (NL), one of the most bitter rivalries in Major League Baseball and in all of North American professional sports.

- Cardinals–Cubs rivalry

The Cubs are one of two major league teams based in Chicago; the other, the Chicago White Sox, is a member of the American League (AL) Central division.

- Chicago Cubs

The White Sox are one of two MLB teams based in Chicago, the other being the Chicago Cubs of the National League (NL) Central division.

- Chicago White Sox

In two of these championships, the Browns met the Chicago White Stockings, now the Chicago Cubs, launching the enduring Cardinals–Cubs rivalry.

- St. Louis Cardinals

Both seasons resulted in matchups with the St. Louis Brown Stockings, with the clubs tying in 1885 and with St. Louis winning in 1886.

- Chicago Cubs

This was the genesis of what would eventually become one of the greatest rivalries in sports.

- Chicago Cubs

La Russa went on to manage in six World Series (winning three) with the Oakland A's and St. Louis Cardinals, ending up in the Hall of Fame as the third-winningest manager of all time.

- Chicago White Sox

Legendary announcer Harry Caray began his career in St. Louis, broadcasting on KMOX radio for 24 seasons, before moving to Chicago in 1971, announcing 11 seasons for the White Sox before moving to the North Side and becoming a staple of WGN radio and television broadcasts for the Cubs from 1982 until his death before the 1998 season.

- Cardinals–Cubs rivalry

In 1962, the Cardinals became the first National League team (and the second in all of Major League Baseball after the Chicago White Sox in 1960) to display players' names on the back of their jerseys.

- St. Louis Cardinals

Through the 1953 season, the two teams were located fairly close to each other (including the 1901 season when the Browns were the Milwaukee Brewers), and could have been seen as the American League equivalent of the Cardinals–Cubs rivalry, being that Chicago and St. Louis have for years been connected by the same highway (U.S. Route 66 and now Interstate 55).

- Chicago White Sox

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