Cholesterol embolism

cholesterol embolicholesterolCholesterol emboluspurple toe syndromeatheroembolic diseaseAtheroembolic renal diseaseembolism, cholesterolpurple toes syndrome
Cholesterol embolism occurs when cholesterol is released, usually from an atherosclerotic plaque, and travels as an embolus in the bloodstream to lodge (as an embolism) causing an obstruction in blood vessels further away.wikipedia
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Livedo reticularis

lacy skin pigmentation
Most commonly this causes skin symptoms (usually livedo reticularis), gangrene of the extremities and sometimes kidney failure; problems with other organs may arise, depending on the site at which the cholesterol crystals enter the bloodstream.

Hollenhorst plaque

Hollenhorst's plaqueplaques of Hollenhorst
Emboli to the eye can be seen by ophthalmoscopy and are known as plaques of Hollenhorst.
A Hollenhorst plaque is a cholesterol embolus that is seen in a blood vessel of the retina.

Embolus

embolibreaking off, and then traveling in the bloodstreamembolic event
Cholesterol embolism occurs when cholesterol is released, usually from an atherosclerotic plaque, and travels as an embolus in the bloodstream to lodge (as an embolism) causing an obstruction in blood vessels further away.

Cholesterol

total cholesteroldietary cholesterolserum cholesterol
Cholesterol embolism occurs when cholesterol is released, usually from an atherosclerotic plaque, and travels as an embolus in the bloodstream to lodge (as an embolism) causing an obstruction in blood vessels further away.

Atheroma

atherosclerotic plaqueplaqueatheromatous plaque
Cholesterol embolism occurs when cholesterol is released, usually from an atherosclerotic plaque, and travels as an embolus in the bloodstream to lodge (as an embolism) causing an obstruction in blood vessels further away.

Embolism

embolicerebral embolismembolus
Cholesterol embolism occurs when cholesterol is released, usually from an atherosclerotic plaque, and travels as an embolus in the bloodstream to lodge (as an embolism) causing an obstruction in blood vessels further away.

Blood vessel

vascularblood vesselsintravascular
Cholesterol embolism occurs when cholesterol is released, usually from an atherosclerotic plaque, and travels as an embolus in the bloodstream to lodge (as an embolism) causing an obstruction in blood vessels further away.

Gangrene

gangrenousdry gangrenefestering
Most commonly this causes skin symptoms (usually livedo reticularis), gangrene of the extremities and sometimes kidney failure; problems with other organs may arise, depending on the site at which the cholesterol crystals enter the bloodstream. Embolism to the legs causes a mottled appearance and purple discoloration of the toes, small infarcts and areas of gangrene due to tissue death that usually appear black, and areas of the skin that assume a marbled pattern known as livedo reticularis.

Kidney failure

renal failurekidney problemsrenal impairment
Most commonly this causes skin symptoms (usually livedo reticularis), gangrene of the extremities and sometimes kidney failure; problems with other organs may arise, depending on the site at which the cholesterol crystals enter the bloodstream. Kidney involvement leads to the symptoms of kidney failure, which are non-specific but usually cause nausea, reduced appetite (anorexia), raised blood pressure (hypertension), and occasionally the various symptoms of electrolyte disturbance such as an irregular heartbeat.

Cholesterol crystal

cholesterol crystals
Most commonly this causes skin symptoms (usually livedo reticularis), gangrene of the extremities and sometimes kidney failure; problems with other organs may arise, depending on the site at which the cholesterol crystals enter the bloodstream.

Kidney

kidneysrenalkidney disorder
When the kidneys are involved, the disease is referred to as atheroembolic renal disease.

Biopsy

biopsiestissue biopsybiopsied
The diagnosis usually involves biopsy (removing a tissue sample) from an affected organ.

Statin

statinsHMG-CoA reductase inhibitorHMG-CoA reductase inhibitors
Cholesterol embolism is treated by removing the cause and giving supportive therapy; statin drugs have been found to improve the prognosis.

Symptom

symptomsnon-specific symptomssymptomatic
Non-specific symptoms often described are fever, muscle ache and weight loss.

Fever

pyrexiafebrileague
Non-specific symptoms often described are fever, muscle ache and weight loss.

Myalgia

muscle painmuscle achesmuscle pains
Non-specific symptoms often described are fever, muscle ache and weight loss.

Weight loss

weight-losslose weightlosing weight
Non-specific symptoms often described are fever, muscle ache and weight loss.

Toe

halluxbig toetoes
Embolism to the legs causes a mottled appearance and purple discoloration of the toes, small infarcts and areas of gangrene due to tissue death that usually appear black, and areas of the skin that assume a marbled pattern known as livedo reticularis.

Infarction

infarctinfarctedinfarcts
Embolism to the legs causes a mottled appearance and purple discoloration of the toes, small infarcts and areas of gangrene due to tissue death that usually appear black, and areas of the skin that assume a marbled pattern known as livedo reticularis.

Necrosis

necroticnecrotizingnecrotic tissue
Embolism to the legs causes a mottled appearance and purple discoloration of the toes, small infarcts and areas of gangrene due to tissue death that usually appear black, and areas of the skin that assume a marbled pattern known as livedo reticularis.

Livedoid vasculitis

Livedoid vasculopathyAtrophie blanchelivedo reticularis
Embolism to the legs causes a mottled appearance and purple discoloration of the toes, small infarcts and areas of gangrene due to tissue death that usually appear black, and areas of the skin that assume a marbled pattern known as livedo reticularis.

Nausea

nauseousnauseatedvomiting
Kidney involvement leads to the symptoms of kidney failure, which are non-specific but usually cause nausea, reduced appetite (anorexia), raised blood pressure (hypertension), and occasionally the various symptoms of electrolyte disturbance such as an irregular heartbeat.

Appetite

appetite lossappetitiveappetitive behavior
Kidney involvement leads to the symptoms of kidney failure, which are non-specific but usually cause nausea, reduced appetite (anorexia), raised blood pressure (hypertension), and occasionally the various symptoms of electrolyte disturbance such as an irregular heartbeat.

Anorexia (symptom)

anorexialoss of appetitedecreased appetite
Kidney involvement leads to the symptoms of kidney failure, which are non-specific but usually cause nausea, reduced appetite (anorexia), raised blood pressure (hypertension), and occasionally the various symptoms of electrolyte disturbance such as an irregular heartbeat.

Blood pressure

systolic blood pressurediastolic blood pressurearterial blood pressure
Kidney involvement leads to the symptoms of kidney failure, which are non-specific but usually cause nausea, reduced appetite (anorexia), raised blood pressure (hypertension), and occasionally the various symptoms of electrolyte disturbance such as an irregular heartbeat.