A report on Clonazepam

Brand name clonazepam tablets
Klonopin 0.5 mg tablet
Klonopin 1 mg tablet
Klonopin 2 mg tablet
Clonazepam orally disintegrating tablet, 0.25 mg

Medication used to prevent and treat seizures, panic disorder, anxiety, and the movement disorder known as akathisia.

- Clonazepam

23 related topics with Alpha

Overall

Structural formula of benzodiazepines.

Benzodiazepine

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Fusion of a benzene ring and a diazepine ring.

Fusion of a benzene ring and a diazepine ring.

Structural formula of benzodiazepines.
Midazolam 1 & 5 mg/mL injections (Canada)
Temazepam (Normison) 10 mg tablets
Addiction experts in psychiatry, chemistry, pharmacology, forensic science, epidemiology, and the police and legal services engaged in delphic analysis regarding 20 popular recreational drugs. Benzodiazepines were ranked in this graph 7th in dependence, physical harm, and social harm.
Diazepam 2 mg and 5 mg diazepam tablets, which are commonly used in the treatment of benzodiazepine withdrawal.
Chlordiazepoxide 5 mg capsules, which are sometimes used as an alternative to diazepam for benzodiazepine withdrawal. Like diazepam it has a long elimination half-life and long-acting active metabolites.
Schematic diagram of the (α1)2(β2)2(γ2) GABAA receptor complex that depicts the five-protein subunits that form the receptor, the chloride (Cl−) ion channel pore at the center, the two GABA active binding sites at the α1 and β2 interfaces and the benzodiazepine (BZD) allosteric binding site at the α1 and γ2 interface.
Left: The 1,4-benzodiazepine ring system. Right: 5-phenyl-1H-benzo[e] [1,4]diazepin-2(3H)-one forms the skeleton of many of the most common benzodiazepine pharmaceuticals, such as diazepam (7-chloro-1-methyl substituted).
A pharmacophore model of the benzodiazepine binding site on the GABAA receptor. White sticks represent the carbon atoms of the benzodiazepine diazepam, while green represents carbon atoms of the nonbenzodiazepine CGS-9896. Red and blue sticks are oxygen and nitrogen atoms that are present in both structures. The red spheres labeled H1 and H2/A3 are, respectively, hydrogen bond donating and accepting sites in the receptor, while L1, L2, and L3 denote lipophilic binding sites.
The molecular structure of chlordiazepoxide, the first benzodiazepine. It was marketed by Hoffmann–La Roche from 1960 branded as Librium.
Xanax (alprazolam) 2 mg tri-score tablets

In a hospital environment, intravenous clonazepam, lorazepam, and diazepam are first-line choices.

Diazepam tablets (10, 5, and 2 mg)

Diazepam

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Medicine of the benzodiazepine family that acts as an anxiolytic.

Medicine of the benzodiazepine family that acts as an anxiolytic.

Diazepam tablets (10, 5, and 2 mg)
5 mg Valium Roche packaging Australia

Other classical benzodiazepines include chlordiazepoxide, clonazepam, lorazepam, oxazepam, nitrazepam, temazepam, flurazepam, bromazepam, and clorazepate.

Carbamazepine

Anticonvulsant

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Anticonvulsants (also known as antiepileptic drugs or recently as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.

Anticonvulsants (also known as antiepileptic drugs or recently as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.

Carbamazepine

Clonazepam (1974).

Someone with a panic attack, being reassured by another person.

Panic disorder

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Mental and behavioral disorder, specifically an anxiety disorder characterized by reoccurring unexpected panic attacks.

Mental and behavioral disorder, specifically an anxiety disorder characterized by reoccurring unexpected panic attacks.

Someone with a panic attack, being reassured by another person.
Age-standardized disability-adjusted life year rates for panic disorder per 100,000 inhabitants in 2004.
no data
less than 95
95–96.5
96.5–98
98–99.5
99.5–101
101–102.5
102.5–104
104–105.5
105.5–107
107–108.5
108.5–110
more than 110

Clonazepam, an anticonvulsant benzodiazepine with a long half-life, has been successful in keeping the condition under control.

Effects of long-term benzodiazepine use

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The effects of long-term benzodiazepine use include drug dependence and neurotoxicity as well as the possibility of adverse effects on cognitive function, physical health, and mental health.

The effects of long-term benzodiazepine use include drug dependence and neurotoxicity as well as the possibility of adverse effects on cognitive function, physical health, and mental health.

Diazepam and clonazepam have been found to have long-lasting, but not permanent, immunotoxic effects in fetuses of rats.

Diazepam is sometimes used in the treatment of benzodiazepine withdrawal.

Benzodiazepine withdrawal syndrome

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Cluster of signs and symptoms that emerge when a person who has been taking benzodiazepines, either medically or recreationally, and has developed a physical dependence, undergoes dosage reduction or discontinuation.

Cluster of signs and symptoms that emerge when a person who has been taking benzodiazepines, either medically or recreationally, and has developed a physical dependence, undergoes dosage reduction or discontinuation.

Diazepam is sometimes used in the treatment of benzodiazepine withdrawal.
Chlordiazepoxide, 5 mg capsules, are sometimes used as an alternative to diazepam for benzodiazepine withdrawal. Like diazepam, it has a long elimination half-life and long-acting active metabolites.

Benzodiazepines with a half-life of more than 24 hours include chlordiazepoxide, diazepam, clobazam, clonazepam, chlorazepinic acid, ketazolam, medazepam, nordazepam, and prazepam.

Phenobarbital

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Medication of the barbiturate type.

Medication of the barbiturate type.

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Among anti-convulsant drugs, behavioural disturbances occur most frequently with clonazepam and phenobarbital.

Roche

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Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics.

Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics.

Participation certificate of the F. Hoffmann-LaRoche & Co AG, issued 15 January 1932
Tamiflu box

Klonopin/Rivotril (clonazepam), for epilepsy and anxiety disorders.

Generalized 3 Hz spike-and-wave discharges on an electroencephalogram

Status epilepticus

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Single seizure lasting more than 5 minutes or 2 or more seizures within a 5-minute period without the person returning to normal between them.

Single seizure lasting more than 5 minutes or 2 or more seizures within a 5-minute period without the person returning to normal between them.

Generalized 3 Hz spike-and-wave discharges on an electroencephalogram
Diazepam that can be inserted rectally is often prescribed to caregivers of people with epilepsy. This enables treatment of multiple seizures prior to being able to seek medical care.

In several countries outside North America, such as the Netherlands, intravenous clonazepam is regarded as the drug of first choice.

Primidone

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Barbiturate medication that is used to treat partial and generalized seizures, as well as essential tremors.

Barbiturate medication that is used to treat partial and generalized seizures, as well as essential tremors.

Dupuytren's contracture of the fourth digit (ring finger).
Radiograph of a rickets sufferer

Other pharmacological agents include alprazolam, clonazepam, atenolol, sotalol, nadolol, clozapine, nimodipine, and botulinum toxin A.