A report on Estrogen receptor and Coumestrol

A dimer of the ligand-binding region of ERβ (PDB rendering based on ).
The domain structures of ERα and ERβ, including some of the known phosphorylation sites involved in ligand-independent regulation.
A dimer of the ligand-binding region of ERα (PDB rendering based on ).
Nolvadex (tamoxifen) 20 mg
Arimidex (anastrozole) 1 mg

However, continued exposure inhibited the growth of the uterus and decreased levels of estrogen receptors within uterine tissue.

- Coumestrol

Phytoestrogens (e.g., coumestrol, daidzein, genistein, miroestrol)

- Estrogen receptor
A dimer of the ligand-binding region of ERβ (PDB rendering based on ).

2 related topics with Alpha

Overall

Estrogen receptor alpha

0 links

Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen.

Phytoestrogens (e.g., coumestrol, daidzein, genistein, miroestrol)

Estradiol, the major estrogen sex hormone in humans and a widely used medication.

Estrogen

0 links

Category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics.

Category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics.

Estradiol, the major estrogen sex hormone in humans and a widely used medication.
Reference ranges for the blood content of estradiol, the primary type of estrogen, during the menstrual cycle.
Steroidogenesis, showing estrogens at bottom right as in pink triangle.

Once inside the cell, they bind to and activate estrogen receptors (ERs) which in turn modulate the expression of many genes.

Plant products with estrogenic activity are called phytoestrogens (e.g., coumestrol, daidzein, genistein, miroestrol).