Genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine.- Cystic fibrosis
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Inflammatory condition of the lung primarily affecting the small air sacs known as alveoli.
Risk factors for pneumonia include cystic fibrosis, chronic obstructive pulmonary disease (COPD), sickle cell disease, asthma, diabetes, heart failure, a history of smoking, a poor ability to cough (such as following a stroke), and a weak immune system.
Inflammation of the mucous membranes that line the sinuses resulting in symptoms that may include thick nasal mucus, a plugged nose, and facial pain.
Recurrent episodes are more likely in persons with asthma, cystic fibrosis, and poor immune function.
Failure to thrive (FTT), also known as weight faltering or faltering growth, indicates insufficient weight gain or absence of appropriate physical growth in children.
Disorders that cause difficulties absorbing or digesting nutrients, such as Crohn's disease, cystic fibrosis, or celiac disease, can present with abdominal symptoms.
Surgical procedure in which one or both lungs are replaced by lungs from a donor.
With other lung diseases such as cystic fibrosis, it is imperative that a recipient receive two lungs.
Membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene.
Mutations of the CFTR gene affecting chloride ion channel function lead to dysregulation of epithelial lining fluid (mucus) transport in the lung, pancreas and other organs, resulting in cystic fibrosis.
Health problem caused by one or more abnormalities in the genome.
Examples of this type of disorder are albinism, medium-chain acyl-CoA dehydrogenase deficiency, cystic fibrosis, sickle cell disease, Tay–Sachs disease, Niemann–Pick disease, spinal muscular atrophy, and Roberts syndrome.
Pathological wound healing in which connective tissue replaces normal parenchymal tissue to the extent that it goes unchecked, leading to considerable tissue remodelling and the formation of permanent scar tissue.
Used to identify changes in DNA sequence or chromosome structure.
Carrier testing - used to identify people who carry one copy of a gene mutation that, when present in two copies, causes a genetic disorder. This type of testing is offered to individuals who have a family history of a genetic disorder and to people in ethnic groups with an increased risk of specific genetic conditions. If both parents are tested, the test can provide information about a couple's risk of having a child with a genetic condition like cystic fibrosis.
Common encapsulated, Gram-negative, strict aerobic , Rod-shaped bacterium that can cause disease in plants and animals, including humans.
The organism is considered opportunistic insofar as serious infection often occurs during existing diseases or conditions – most notably cystic fibrosis and traumatic burns.
Deformity of the finger or toe nails associated with a number of diseases, mostly of the heart and lungs.
Clubbing is associated with lung cancer, lung infections, interstitial lung disease, cystic fibrosis, or cardiovascular disease.