Cystic fibrosis

CFCystic fibrosis of the pancreasdiseaseMucoviscidosemucovisidosis
Cystic fibrosis (CF) is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine.wikipedia
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Pneumonia

bronchopneumoniabronchial pneumoniaNecrotizing pneumonia
Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections.
Risk factors include cystic fibrosis, chronic obstructive pulmonary disease (COPD), asthma, diabetes, heart failure, a history of smoking, a poor ability to cough such as following a stroke, and a weak immune system.

Lung transplantation

lung transplantdouble lung transplantlung
Lung transplantation may be an option if lung function continues to worsen.
With other lung diseases such as cystic fibrosis, it is imperative that a recipient receive two lungs.

Sinusitis

sinus infectionrhinosinusitischronic sinusitis
Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males.
Recurrent episodes are more likely in persons with asthma, cystic fibrosis, and poor immune function.

Nail clubbing

clubbingdigital clubbingfinger clubbing
Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males.
Clubbing is associated with lung cancer, lung infections, interstitial lung disease, cystic fibrosis, or cardiovascular disease.

Failure to thrive

growth failurepoor growthfailed to thrive
Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males.

Sweat test

cystic fibrosis
The condition is diagnosed by a sweat test and genetic testing.
It is used to screen for cystic fibrosis (CF).

Genetic disorder

genetic diseasegenetic disordersgenetic diseases
Cystic fibrosis (CF) is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine.
Examples of this type of disorder are Albinism, Medium-chain acyl-CoA dehydrogenase deficiency, cystic fibrosis, sickle-cell disease, Tay–Sachs disease, Niemann-Pick disease, spinal muscular atrophy, and Roberts syndrome.

Steatorrhea

steatorrhoeafatty stoolfatty feces
Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males.

Bronchiectasis

bronchectasisbronchiectasiadilated
In later stages, changes in the architecture of the lung, such as pathology in the major airways (bronchiectasis), further exacerbate difficulties in breathing.
Bronchiectasis may result from a number of infectious and acquired causes, including pneumonia, tuberculosis, immune system problems, as well as the genetic disorder cystic fibrosis.

Pancreatic enzymes (medication)

pancrelipasepancreatinliprotamase
Pancreatic enzyme replacement and fat-soluble vitamin supplementation are important, especially in the young.
These pancreatic problems may be due to cystic fibrosis, surgical removal of the pancreas, long term pancreatitis, or pancreatic cancer, among others.

Allergic bronchopulmonary aspergillosis

aspergillosis, allergic bronchopulmonary '''A'''BPAas described above
Among these is allergic bronchopulmonary aspergillosis, in which the body's response to the common fungus Aspergillus fumigatus causes worsening of breathing problems.
It occurs most often in people with asthma or cystic fibrosis.

Pseudomonas aeruginosa

P. aeruginosaPseudomonasPseudomonas aeruginosa'' infection
Staphylococcus aureus, Haemophilus influenzae, and Pseudomonas aeruginosa are the three most common organisms causing lung infections in CF patients.
The organism is considered opportunistic insofar as serious infection often occurs during existing diseases or conditions – most notably cystic fibrosis and traumatic burns.

Genetic testing

DNA testingDNA analysisDNA test
The condition is diagnosed by a sweat test and genetic testing.
There is a variety of DTC tests, ranging from tests for breast cancer alleles to mutations linked to cystic fibrosis.

Exocrine pancreatic insufficiency

pancreatic insufficiencyexocrine insufficiencyEPI
Exocrine pancreatic insufficiency occurs in the majority (85% to 90%) of patients with CF.
EPI is found in humans afflicted with cystic fibrosis and Shwachman–Diamond syndrome, and is common in dogs.

Fibrosis

fibroticscarringfibrogenic
The name "cystic fibrosis" refers to the characteristic fibrosis and cysts that form within the pancreas.

Pneumothorax

collapsed lungtension pneumothoraxpunctured lung
People with CF are susceptible to getting a pneumothorax.
The sudden onset of breathlessness in someone with chronic obstructive pulmonary disease (COPD), cystic fibrosis, or other serious lung diseases should therefore prompt investigations to identify the possibility of a pneumothorax.

Pancreatitis

inflammation of the pancreasgallstone pancreatitispancreatic inflammation
These secretions block the exocrine movement of the digestive enzymes into the duodenum and result in irreversible damage to the pancreas, often with painful inflammation (pancreatitis).
Other causes include high levels of blood fats, high blood calcium, some medications, and certain genetic disorders such as cystic fibrosis among others.

Vitamin

vitaminsfat-soluble vitaminsfat-soluble vitamin
Pancreatic enzyme replacement and fat-soluble vitamin supplementation are important, especially in the young.
Fat-soluble vitamin deficiency due to malabsorption is of particular significance in cystic fibrosis.

Hemoptysis

coughing up bloodhaemoptysishæmoptysis
Other signs include coughing up blood (hemoptysis), high blood pressure in the lung (pulmonary hypertension), heart failure, difficulties getting enough oxygen to the body (hypoxia), and respiratory failure requiring support with breathing masks, such as bilevel positive airway pressure machines or ventilators.
Less common causes include aspergilloma, bronchiectasis, coccidioidomycosis, pulmonary embolism, pneumonic plague, and cystic fibrosis.

Intussusception (medical disorder)

intussusceptionictusintro-susception
In addition to the pancreas problems, people with cystic fibrosis experience more heartburn, intestinal blockage by intussusception, and constipation.
Risk factors in children include certain infections, diseases like cystic fibrosis, and intestinal polyps.

Nasal polyp

nasal polypsnasal polyposispolyps
Individuals with CF may develop overgrowth of the nasal tissue (nasal polyps) due to inflammation from chronic sinus infections.
They occur more commonly among people who have allergies, cystic fibrosis, aspirin sensitivity, or certain infections.

Infertility

infertilesterilesterility
Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males.
Cystic fibrosis can lead to infertility in men.

Chest physiotherapy

Chest physical therapy
Airway clearance techniques such as chest physiotherapy have some short-term benefit, but long-term effects are unclear.
CPT are treatments which are performed on people suffering from mucus dysfunction in Respiratory disease conditions like Asthma, Chronic obstructive pulmonary disease, Bronchitis, Bronchiectasis and Cystic fibrosis.

Distal intestinal obstruction syndrome

Older individuals with CF may develop distal intestinal obstruction syndrome when thickened feces cause intestinal blockage.
Distal intestinal obstruction syndrome (DIOS) involves obstruction of the distal part of the small intestines by thickened intestinal content and occurs in about 20% of mainly adult individuals with cystic fibrosis.

Pancreas

pancreaticexocrine pancreaspancreatic development
Cystic fibrosis (CF) is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. The name "cystic fibrosis" refers to the characteristic fibrosis and cysts that form within the pancreas.
It shares many similar causes, with the most common being chronic alcohol use, with other causes including recurrent acute episodes and cystic fibrosis.