A report on DNA profiling
Process of determining an individual's DNA characteristics.
- DNA profiling30 related topics with Alpha
Alec Jeffreys
6 linksSir Alec John Jeffreys, (born 9 January 1950) is a British geneticist known for developing techniques for genetic fingerprinting and DNA profiling which are now used worldwide in forensic science to assist police detective work and to resolve paternity and immigration disputes.
Microsatellite
5 linksTract of repetitive DNA in which certain DNA motifs are repeated, typically 5–50 times.
Tract of repetitive DNA in which certain DNA motifs are repeated, typically 5–50 times.
Microsatellites are often referred to as short tandem repeats (STRs) by forensic geneticists and in genetic genealogy, or as simple sequence repeats (SSRs) by plant geneticists.
DNA
5 linksPolymer composed of two polynucleotide chains that coil around each other to form a double helix carrying genetic instructions for the development, functioning, growth and reproduction of all known organisms and many viruses.
Polymer composed of two polynucleotide chains that coil around each other to form a double helix carrying genetic instructions for the development, functioning, growth and reproduction of all known organisms and many viruses.
In technology, these sequence-specific nucleases are used in molecular cloning and DNA fingerprinting.
Polymerase chain reaction
3 linksMethod widely used to rapidly make millions to billions of copies (complete or partial) of a specific DNA sample, allowing scientists to take a very small sample of DNA and amplify it (or a part of it) to a large enough amount to study in detail.
Method widely used to rapidly make millions to billions of copies (complete or partial) of a specific DNA sample, allowing scientists to take a very small sample of DNA and amplify it (or a part of it) to a large enough amount to study in detail.
Applications of the technique include DNA cloning for sequencing, gene cloning and manipulation, gene mutagenesis; construction of DNA-based phylogenies, or functional analysis of genes; diagnosis and monitoring of genetic disorders; amplification of ancient DNA; analysis of genetic fingerprints for DNA profiling (for example, in forensic science and parentage testing); and detection of pathogens in nucleic acid tests for the diagnosis of infectious diseases.
DNA paternity testing
2 linksDNA paternity testing is the use of DNA profiles to determine whether an individual is the biological parent of another individual.
Colin Pitchfork
2 linksBritish double child-murderer and rapist.
British double child-murderer and rapist.
He was the first person convicted of rape and murder using DNA profiling after he murdered two girls in neighbouring Leicestershire villages, the first in Narborough, in November 1983, and the second in Enderby in July 1986.
Variable number tandem repeat
2 linksLocation in a genome where a short nucleotide sequence is organized as a tandem repeat.
Location in a genome where a short nucleotide sequence is organized as a tandem repeat.
Their analysis is useful in genetics and biology research, forensics, and DNA fingerprinting.
United Kingdom National DNA Database
4 linksNational DNA Database that was set up in 1995.
National DNA Database that was set up in 1995.
Such an approach has been advocated by the inventor of genetic fingerprinting, Alec Jeffreys.
University of Leicester
1 linksPublic research university based in Leicester, England.
Public research university based in Leicester, England.
The university is known for the invention of genetic fingerprinting, and for the discovery and identification of the remains of King Richard III.
Minisatellite
4 linksTract of repetitive DNA in which certain DNA motifs are typically repeated 5-50 times.
Tract of repetitive DNA in which certain DNA motifs are typically repeated 5-50 times.
Discovering their high level of variability, Sir Alec Jeffreys developed DNA fingerprinting based on minisatellites, solving the first immigration case by DNA in 1985, and the first forensic murder case, the Enderby murders in the United Kingdom, in 1986.