Depressant

depressantsdownerscentral depressantcentral nervous system depressantsCNS depressantscentral nervous system depressantdepressingdepressiondepressant drugsCNS-depressant
A depressant, or central depressant, is a drug that lowers neurotransmission levels, which is to depress or reduce arousal or stimulation, in various areas of the brain.wikipedia
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Alcohol (drug)

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Alcohol is a very prominent depressant.
Among other effects, alcohol produces a mood lift and euphoria, decreased anxiety, increased sociability, sedation, impairment of cognitive, memory, motor, and sensory function, and generalized depression of central nervous system function.

Drug

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A depressant, or central depressant, is a drug that lowers neurotransmission levels, which is to depress or reduce arousal or stimulation, in various areas of the brain.
These drugs are divided into different groups like: stimulants, depressants, antidepressants, anxiolytics, antipsychotics, and hallucinogens.

Anticonvulsant

anticonvulsantsantiepilepticantiepileptic drugs
When depressants are used, effects often include ataxia, anxiolysis, pain relief, sedation or somnolence, and cognitive/memory impairment, as well as in some instances euphoria, dissociation, muscle relaxation, lowered blood pressure or heart rate, respiratory depression, and anticonvulsant effects, and even similar effects of General Anaesthesia and/or death at high doses. Benzodiazepines enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA A receptor, resulting in sedative, hypnotic (sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant properties; also seen in the applied pharmacology of high doses of many shorter-acting benzodiazepines are amnesic-dissociative actions.
Barbiturates are drugs that act as central nervous system (CNS) depressants, and by virtue of this they produce a wide spectrum of effects, from mild sedation to anesthesia.

Benzodiazepine

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Other depressants can include drugs like Xanax (a benzodiazepine) and a number of opiates.
When combined with other central nervous system (CNS) depressants such as alcoholic drinks and opioids, the potential for toxicity and fatal overdose increases.

Heart rate

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When depressants are used, effects often include ataxia, anxiolysis, pain relief, sedation or somnolence, and cognitive/memory impairment, as well as in some instances euphoria, dissociation, muscle relaxation, lowered blood pressure or heart rate, respiratory depression, and anticonvulsant effects, and even similar effects of General Anaesthesia and/or death at high doses.

Alprazolam

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Other depressants can include drugs like Xanax (a benzodiazepine) and a number of opiates.
Like all central nervous system depressants, alprazolam in larger-than-normal doses can cause significant deterioration in alertness and increase drowsiness, especially in those unaccustomed to the drug's effects.

Recreational drug use

recreational drugdrug userecreational drugs
Ethanol is the oldest recreational drug still used by humans.
Generally, recreational drugs are in three categories: depressants (drugs that induce a feeling of relaxation and calm); stimulants (drugs that induce a sense of energy and alertness); and hallucinogens (drugs that induce perceptual distortions such as hallucination).

Psychoactive drug

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An alcoholic beverage is a drink that contains alcohol (also known formally as ethanol), an anesthetic that has been used as a psychoactive drug for several millennia.

Ethanol

alcoholbioethanolethyl alcohol
Ethanol is the oldest recreational drug still used by humans. An alcoholic beverage is a drink that contains alcohol (also known formally as ethanol), an anesthetic that has been used as a psychoactive drug for several millennia.
As a central nervous system depressant, ethanol is one of the most commonly consumed psychoactive drugs.

Euphoria

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When depressants are used, effects often include ataxia, anxiolysis, pain relief, sedation or somnolence, and cognitive/memory impairment, as well as in some instances euphoria, dissociation, muscle relaxation, lowered blood pressure or heart rate, respiratory depression, and anticonvulsant effects, and even similar effects of General Anaesthesia and/or death at high doses.
Certain depressants can produce euphoria; some of the euphoriant drugs in this class include alcohol in moderate doses, γ-hydroxybutyric acid, and ketamine.

Hypoventilation

respiratory depressiondecreased effort to breathedecreased breathing
When depressants are used, effects often include ataxia, anxiolysis, pain relief, sedation or somnolence, and cognitive/memory impairment, as well as in some instances euphoria, dissociation, muscle relaxation, lowered blood pressure or heart rate, respiratory depression, and anticonvulsant effects, and even similar effects of General Anaesthesia and/or death at high doses.
Many different central nervous system (CNS) depressant drugs such as ethanol, benzodiazepines, barbiturates, GHB, sedatives and opioids produce respiratory depression when taken in large or excessive doses, or mixed with other depressants.

Insomnia

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These properties make benzodiazepines useful in treating anxiety, insomnia, agitation, seizures, muscle spasms, alcohol withdrawal and as a premedication for medical or dental procedures.

Barbiturate

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However, they are much less toxic than their predecessors, the barbiturates, and death rarely results when a benzodiazepine is the only drug taken; however, when combined with other central nervous system depressants such as alcohol and opiates, the potential for toxicity and fatal overdose increases.
A barbiturate is a drug that acts as a central nervous system depressant, and can therefore produce a wide range of effects, from mild sedation to death.

Alcoholic drink

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However, they are much less toxic than their predecessors, the barbiturates, and death rarely results when a benzodiazepine is the only drug taken; however, when combined with other central nervous system depressants such as alcohol and opiates, the potential for toxicity and fatal overdose increases.
Alcohol is a depressant, which in low doses causes euphoria, reduces anxiety, and improves sociability.

Hypnotic

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Benzodiazepines enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA A receptor, resulting in sedative, hypnotic (sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant properties; also seen in the applied pharmacology of high doses of many shorter-acting benzodiazepines are amnesic-dissociative actions.
Benzodiazepines are not without their drawbacks; substance dependence is possible, and deaths from overdoses sometimes occur, especially in combination with alcohol and/or other depressants.

Stimulant

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Stimulants or "uppers" increase mental and/or physical function, hence the opposite drug class of depressants is stimulants, not antidepressants.

Opioid

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An overdose or concurrent use with other depressant drugs like benzodiazepines commonly results in death from respiratory depression.

Morphine

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However, recent studies have been able to show some impairments caused by morphine, which is not surprising, given that morphine is a central nervous system depressant.

Substance abuse

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Benzodiazepines are commonly misused and taken in combination with other drugs of abuse.

Phenibut

Phenibut, sold under the brand names Anvifen, Fenibut, and Noofen among others, is a central nervous system depressant with anxiolytic effects, and is used to treat anxiety, among other indications.

Diazepam

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The first such drug, chlordiazepoxide (Librium), was discovered accidentally by Leo Sternbach in 1955, and made available in 1960 by Hoffmann–La Roche, which has also marketed the benzodiazepine diazepam (Valium) since 1963.
The benzodiazepines are also far less dangerous; death rarely results from diazepam overdose, except in cases where it is consumed with large amounts of other depressants (such as alcohol or opioids).

Central nervous system depression

CNS depressantCNS depressioncentral nervous system depressant
Depression of the central nervous system is generally caused by the use of depressant drugs such as ethanol, opioids, barbiturates, benzodiazepines, general anesthetics, and anticonvulsants such as pregabalin used to treat epilepsy.

Gamma-Hydroxybutyric acid

GHBγ-hydroxybutyric acidgamma-hydroxybutyrate
GHB is a central nervous system depressant used as an intoxicant.

Inhalant

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Solvents such as toluene and gasoline act as depressants, causing users to feel relaxed and sleepy.

Heroin

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However, many fatalities reported as overdoses are probably caused by interactions with other depressant drugs such as alcohol or benzodiazepines.