Dextroamphetamine

Dexedrined-amphetamineDexamphetamineDexamfetamine D -amphetaminedextroamphetamine sulfate-amphetamineamphetamined''-amphetamineDexadrine
Dextroamphetamine is a central nervous system (CNS) stimulant and an amphetamine enantiomer that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.wikipedia
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Stimulant

stimulantspsychostimulantpsychostimulants
Dextroamphetamine is a central nervous system (CNS) stimulant and an amphetamine enantiomer that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. Newer stimulant medications or awakeness promoting agents with different side effect profiles, such as modafinil, are being investigated and sometimes issued for this reason. In particular, amphetamine may decrease the effects of sedatives and depressants and increase the effects of stimulants and antidepressants.
Numerous studies have demonstrated the effectiveness of drugs such as Adderall (a mixture of salts of amphetamine and dextroamphetamine) in controlling symptoms associated with ADHD.

Substituted amphetamine

amphetaminesamphetaminesubstituted amphetamines
Dextroamphetamine is also used recreationally as a euphoriant and aphrodisiac, and like other amphetamines is used as a club drug for its energetic and euphoric high.
In the 1920s, both methamphetamine and the dextrorotatory optical isomer of amphetamine, dextroamphetamine, were synthesized.

Narcolepsy

narcolepticdifficulty in controlling her sleepdifficulty staying awake
Dextroamphetamine is a central nervous system (CNS) stimulant and an amphetamine enantiomer that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.
The main treatment of excessive daytime sleepiness in narcolepsy is central nervous system stimulants such as methylphenidate, amphetamine, dextroamphetamine, modafinil, and armodafinil.

Levoamphetamine

L-amphetamineLevamfetamine L -amphetamine
The amphetamine molecule exists as two enantiomers, levoamphetamine and dextroamphetamine.
Racemic amphetamine contains two optical isomers, dextroamphetamine and levoamphetamine.

Norepinephrine transporter

NETnorepinephrinenoradrenaline transporter
Dextroamphetamine, like other amphetamines, elicits its stimulating effects via several distinct actions: it inhibits or reverses the transporter proteins for the monoamine neurotransmitters (namely the serotonin, norepinephrine and dopamine transporters) either via trace amine-associated receptor 1 (TAAR1) or in a TAAR1 independent fashion when there are high cytosolic concentrations of the monoamine neurotransmitters and it releases these neurotransmitters from synaptic vesicles via vesicular monoamine transporter 2.
Dextroamphetamine (Dexedrine, Dextrostat), Adderall, methylphenidate (Ritalin, Metadate, Concerta, Daytrana), and lisdexamfetamine (Vyvanse) block reabsorption of the catecholamines dopamine and norepinephrine through monoamine transporters (including NET), thereby increasing levels of these neurotransmitters in the brain.

Amphetamine

Benzedrinespeedamphetamines
Dextroamphetamine is a central nervous system (CNS) stimulant and an amphetamine enantiomer that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.
Amphetamine was discovered in 1887 and exists as two enantiomers: levoamphetamine and dextroamphetamine.

Dexamyl

purple heartsDrinamylFrench Blues
Dextroamphetamine was marketed in various other forms in the following decades, primarily by Smith, Kline, and French, such as several combination medications including a mixture of dextroamphetamine and amobarbital (a barbiturate) sold under the tradename Dexamyl and, in the 1950s, an extended release capsule (the "Spansule").
Dexamyl (or Drinamyl in the UK) was the brand name of a combination drug composed of amobarbital (previously called amylbarbitone) and dextroamphetamine.

Modafinil

ProvigilAlertecList of modafinil analogues
Newer stimulant medications or awakeness promoting agents with different side effect profiles, such as modafinil, are being investigated and sometimes issued for this reason.
The use of dextroamphetamine is no longer approved.

Antidepressant

antidepressantsanti-depressantanti-depressants
In particular, amphetamine may decrease the effects of sedatives and depressants and increase the effects of stimulants and antidepressants.
Psychopharmacologists have also tried adding a stimulant, in particular, d-amphetamine.

Lisdexamfetamine

Vyvanselisdexamfetamine dimesylatelisdexamphetamine
Dextroamphetamine is sometimes prescribed as the inactive prodrug lisdexamfetamine dimesylate, which is converted into dextroamphetamine after absorption.
Lisdexamfetamine is a central nervous system (CNS) stimulant that works after being converted by the body into dextroamphetamine.

Controlled Substances Act

Schedule ISchedule IISchedule III
It quickly became apparent that dextroamphetamine and other amphetamines had a high potential for misuse, although they were not heavily controlled until 1970, when the Comprehensive Drug Abuse Prevention and Control Act was passed by the United States Congress.

Racemic mixture

racemicracemateracemates
Racemic amphetamine was first synthesized under the chemical name "phenylisopropylamine" in Berlin, 1887 by the Romanian chemist Lazar Edeleanu.
A single amphetamine dose combines the neutral sulfate salts of dextroamphetamine and amphetamine, with the dextro isomer of amphetamine saccharate and D/L-amphetamine aspartate monohydrate.

Teva Pharmaceutical Industries

TevaTeva PharmaceuticalsTeva Pharmaceutical
In the United States, immediate release (IR) formulations of dextroamphetamine sulfate are available generically as 5 mg and 10 mg tablets, marketed by Barr (Teva Pharmaceutical Industries), Mallinckrodt Pharmaceuticals, Wilshire Pharmaceuticals, Aurobindo Pharmaceutical USA and CorePharma.

Mallinckrodt

Edward MallinckrodtMallinckrodt Chemical WorksMallinckrodt, Inc.
In the United States, immediate release (IR) formulations of dextroamphetamine sulfate are available generically as 5 mg and 10 mg tablets, marketed by Barr (Teva Pharmaceutical Industries), Mallinckrodt Pharmaceuticals, Wilshire Pharmaceuticals, Aurobindo Pharmaceutical USA and CorePharma.

Central nervous system

CNScentralcentral nervous system (CNS)
Dextroamphetamine is a central nervous system (CNS) stimulant and an amphetamine enantiomer that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.

Enantiomer

enantiomersenantioselectiveenantiopure
Dextroamphetamine is a central nervous system (CNS) stimulant and an amphetamine enantiomer that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.

Nootropic

nootropicscognitive enhancersmart drugs
It is also used as an athletic performance and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant.

Aphrodisiac

aphrodisiacslove potionpro-sexual
Dextroamphetamine is also used recreationally as a euphoriant and aphrodisiac, and like other amphetamines is used as a club drug for its energetic and euphoric high. It is also used as an athletic performance and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant.

Brand

brand namemarquebrands
Pharmaceutical dextroamphetamine sulfate is available as both a brand name and generic drug in a variety of dosage forms.

Generic drug

generic medicationgenericgeneric drugs
Pharmaceutical dextroamphetamine sulfate is available as both a brand name and generic drug in a variety of dosage forms.

Dosage form

dosage formsformformulation
Pharmaceutical dextroamphetamine sulfate is available as both a brand name and generic drug in a variety of dosage forms.

Monoamine neurotransmitter

monoaminemonoaminesmonoamine neurotransmitters
Dextroamphetamine, like other amphetamines, elicits its stimulating effects via several distinct actions: it inhibits or reverses the transporter proteins for the monoamine neurotransmitters (namely the serotonin, norepinephrine and dopamine transporters) either via trace amine-associated receptor 1 (TAAR1) or in a TAAR1 independent fashion when there are high cytosolic concentrations of the monoamine neurotransmitters and it releases these neurotransmitters from synaptic vesicles via vesicular monoamine transporter 2.

Serotonin transporter

SERTserotoninSLC6A4
Dextroamphetamine, like other amphetamines, elicits its stimulating effects via several distinct actions: it inhibits or reverses the transporter proteins for the monoamine neurotransmitters (namely the serotonin, norepinephrine and dopamine transporters) either via trace amine-associated receptor 1 (TAAR1) or in a TAAR1 independent fashion when there are high cytosolic concentrations of the monoamine neurotransmitters and it releases these neurotransmitters from synaptic vesicles via vesicular monoamine transporter 2.

Dopamine transporter

DATdopamineSLC6A3
Dextroamphetamine, like other amphetamines, elicits its stimulating effects via several distinct actions: it inhibits or reverses the transporter proteins for the monoamine neurotransmitters (namely the serotonin, norepinephrine and dopamine transporters) either via trace amine-associated receptor 1 (TAAR1) or in a TAAR1 independent fashion when there are high cytosolic concentrations of the monoamine neurotransmitters and it releases these neurotransmitters from synaptic vesicles via vesicular monoamine transporter 2.

Synaptic vesicle

synaptic vesiclesvesiclesvesicle
Dextroamphetamine, like other amphetamines, elicits its stimulating effects via several distinct actions: it inhibits or reverses the transporter proteins for the monoamine neurotransmitters (namely the serotonin, norepinephrine and dopamine transporters) either via trace amine-associated receptor 1 (TAAR1) or in a TAAR1 independent fashion when there are high cytosolic concentrations of the monoamine neurotransmitters and it releases these neurotransmitters from synaptic vesicles via vesicular monoamine transporter 2.