Dissociative

dissociative anestheticdissociativesDissociative drugdissociationdissociative anaestheticdissociative anestheticsDissociative hallucinogendissociated statedissociative agentdissociative drugs
Dissociatives are a class of hallucinogen which distort perceptions of sight and sound and produce feelings of detachment – dissociation – from the environment and self.wikipedia
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Ketamine

K-holeSpecial KCalypsol
Both Pender (1970) and Johnstone et al. (1959) reported that patients under anaesthesia due to either ketamine or phencyclidine were prone to purposeless movements and had hallucinations (or "dreams" ) during and after anaesthesia. Ketamine and nitrous oxide are club drugs.
Ketamine is also used as a recreational drug for its hallucinogenic and dissociative effects.

Hallucination

hallucinationshallucinatehallucinating
Although many kinds of drugs are capable of such action, dissociatives are unique in that they do so in such a way that they produce hallucinogenic effects, which may include sensory deprivation, dissociation, hallucinations, and dream-like states or trances.
Drug-induced hallucinations are caused by hallucinogens, dissociatives, and deliriants, including many drugs with anticholinergic actions and certain stimulants, which are known to cause visual and auditory hallucinations.

Phencyclidine

PCPangel dustphenylcyclidine
Both Pender (1970) and Johnstone et al. (1959) reported that patients under anaesthesia due to either ketamine or phencyclidine were prone to purposeless movements and had hallucinations (or "dreams" ) during and after anaesthesia.
Chemically, PCP is a member of the arylcyclohexylamine class, and pharmacologically, it is a dissociative anesthetic.

Dissociation (psychology)

dissociationdissociativedissociative state
Although many kinds of drugs are capable of such action, dissociatives are unique in that they do so in such a way that they produce hallucinogenic effects, which may include sensory deprivation, dissociation, hallucinations, and dream-like states or trances.

Nitrous oxide

laughing gasN 2 Onitrous
Ketamine and nitrous oxide are club drugs.
Its colloquial name "laughing gas", coined by Humphry Davy, is due to the euphoric effects upon inhaling it, a property that has led to its recreational use as a dissociative anaesthetic.

Dextromethorphan

DXMVicks Formula 44Creo-Terpin
Dextromethorphan-based cough syrups (often labeled DXM) are taken by some users in higher than medically recommended levels for their dissociative effects.
It is in the morphinan class of medications with sedative, dissociative, and stimulant properties (at lower doses).

Hallucinogen

hallucinogenicpsychedelic drughallucinogens
Although many kinds of drugs are capable of such action, dissociatives are unique in that they do so in such a way that they produce hallucinogenic effects, which may include sensory deprivation, dissociation, hallucinations, and dream-like states or trances. Dissociatives are a class of hallucinogen which distort perceptions of sight and sound and produce feelings of detachment – dissociation – from the environment and self. At sub-anesthetic doses, dissociatives alter many of the same cognitive and perceptual processes affected by other hallucinogenic drugs such as mescaline, LSD, and psilocybin; hence they are also considered hallucinogenic, and psychedelic.
The common types of hallucinogens are psychedelics, dissociatives and deliriants.

Psychedelic drug

psychedelicpsychedelicspsychedelic drugs
At sub-anesthetic doses, dissociatives alter many of the same cognitive and perceptual processes affected by other hallucinogenic drugs such as mescaline, LSD, and psilocybin; hence they are also considered hallucinogenic, and psychedelic.
For instance, 5-MeO-DMT rarely produces the visual effects typical of other psychedelics and ibogaine (a 'complex tryptamine') is also an NMDA receptor antagonist and κ-opioid receptor agonist in addition to being an agonist for the 5-HT 2A receptors, resulting in dissociative effects as well (see dissociatives below).

NMDA receptor antagonist

NMDA antagonistNMDA antagonistsNMDA receptor antagonists
They are commonly used as anesthetics for animals and humans; the state of anesthesia they induce is referred to as dissociative anesthesia.

Depersonalization

depersonalisationdepersonalizeddepersonalised
Perhaps the most significant subjective differences between dissociatives and the classical hallucinogens (such as LSD and mescaline) are the dissociative effects, including: depersonalization, the feeling of being unreal, disconnected from one's self, or unable to control one's actions; and derealization, the feeling that the outside world is unreal or that one is dreaming.
It is an effect of dissociatives and psychedelics, as well as a possible side effect of caffeine, alcohol, amphetamine, and cannabis.

Club drug

club drugsparty drugsdrug use
Ketamine and nitrous oxide are club drugs.
Nitrous oxide is a dissociative inhalant that can cause depersonalisation, derealisation (feeling like the world is not real), dizziness, euphoria, and some sound distortion (flanging).

Derealization

derealisationunrealityFeeling unreal
Perhaps the most significant subjective differences between dissociatives and the classical hallucinogens (such as LSD and mescaline) are the dissociative effects, including: depersonalization, the feeling of being unreal, disconnected from one's self, or unable to control one's actions; and derealization, the feeling that the outside world is unreal or that one is dreaming.
Cannabis, psychedelics, dissociatives, antidepressants, caffeine, nitrous oxide, albuterol, and nicotine can all produce feelings mimicking feelings of derealization, particularly when taken in excess.

Consciousness

consciousconsciouslyhuman consciousness
This is done through reducing or blocking signals to the conscious mind from other parts of the brain.

Sensory deprivation

sense deprivationcover his face with his own garmentdeprivation
Although many kinds of drugs are capable of such action, dissociatives are unique in that they do so in such a way that they produce hallucinogenic effects, which may include sensory deprivation, dissociation, hallucinations, and dream-like states or trances.

Oneirogen

dream-like statesoneirogeniconeirogens
Although many kinds of drugs are capable of such action, dissociatives are unique in that they do so in such a way that they produce hallucinogenic effects, which may include sensory deprivation, dissociation, hallucinations, and dream-like states or trances.

Trance

trance statesystemic trancetrance states
Although many kinds of drugs are capable of such action, dissociatives are unique in that they do so in such a way that they produce hallucinogenic effects, which may include sensory deprivation, dissociation, hallucinations, and dream-like states or trances.

Dopamine

dopaminergic systemDAdopaminergic
Some, which are nonselective in action and affect the dopamine and/or opioid systems, may be capable of inducing euphoria.

Opioid

opioidsopioid-induced constipationopioid analgesic
Some, which are nonselective in action and affect the dopamine and/or opioid systems, may be capable of inducing euphoria.

Euphoria

euphoriceuphorianthigh
Some, which are nonselective in action and affect the dopamine and/or opioid systems, may be capable of inducing euphoria.

Depressant

depressantsdownerscentral depressant
Many dissociatives have general depressant effects and can produce sedation, respiratory depression, analgesia, anesthesia, and ataxia, as well as cognitive and memory impairment and amnesia.

Sedation

sedatedsedatingsedate
Many dissociatives have general depressant effects and can produce sedation, respiratory depression, analgesia, anesthesia, and ataxia, as well as cognitive and memory impairment and amnesia.

Hypoventilation

respiratory depressiondecreased effort to breathedecreased breathing
Many dissociatives have general depressant effects and can produce sedation, respiratory depression, analgesia, anesthesia, and ataxia, as well as cognitive and memory impairment and amnesia.

Analgesic

analgesiaanalgesicspainkillers
Many dissociatives have general depressant effects and can produce sedation, respiratory depression, analgesia, anesthesia, and ataxia, as well as cognitive and memory impairment and amnesia.

Anesthesia

anaesthesiaanestheticanesthetized
Many dissociatives have general depressant effects and can produce sedation, respiratory depression, analgesia, anesthesia, and ataxia, as well as cognitive and memory impairment and amnesia.

Ataxia

gluten ataxiaataxicloss of coordination
Many dissociatives have general depressant effects and can produce sedation, respiratory depression, analgesia, anesthesia, and ataxia, as well as cognitive and memory impairment and amnesia.