Drug overdose

overdoseoverdosingoverdosedoverdosesdrug overdosesheroin overdoseaccidental overdoseODoverdosageprescription drug overdose
A drug overdose (or simply overdose or OD) is the ingestion or application of a drug or other substance in quantities greater than are recommended or generally practiced.wikipedia
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Drug interaction

interactdrug interactionsdrug-drug interaction
The term 'overdose' is often misused as a descriptor for adverse drug reactions or negative drug interactions due to mixing multiple drugs simultaneously.
If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur.

Toxidrome

Intoxicationopioid intoxicationanticholinergic toxidrome
The symptoms can often be divided into differing toxidromes.
It is often the consequence of a drug overdose.

Opioid

opioidsopioid analgesicendogenous opioids
The distribution of naloxone to injection drug users and other opioid drug users decreases the risk of death from overdose.
An overdose or concurrent use with other depressant drugs commonly results in death from respiratory depression.

Suicide

suicidalcommitted suicidesuicides
Drug overdoses are sometimes caused intentionally to commit suicide, parasuicide or as self-harm, but many drug overdoses are accidental, the result of intentional or unintentional misuse of medication.
The most common attempted methods of suicide differ from the most common methods of completion; up to 85% of attempts are via drug overdose in the developed world.

Coma

comatoseunresponsivecomatose state
If this overdose is not treated with chelation therapy, it can lead to death or a permanent coma.
Forty percent of comatose states result from drug poisoning.

Benzodiazepine overdose

overdoseaccidental drug overdosebenzodiazepine overdoses
Benzodiazepine overdose (T42.4)
The most common symptoms of overdose include central nervous system (CNS) depression, impaired balance, ataxia, and slurred speech.

Self-harm

self-mutilationself-injuryself harm
Drug overdoses are sometimes caused intentionally to commit suicide, parasuicide or as self-harm, but many drug overdoses are accidental, the result of intentional or unintentional misuse of medication.
About 10% of admissions to medical wards in the UK are as a result of self-harm, the majority of which are drug overdoses.

Barbiturate overdose

overdose of barbituratesbarbiturate poisoningacute barbiturate poisoning
Barbiturate overdose (T42.3)
Complications of overdose can include noncardiogenic pulmonary edema.

Euphoria

euphoriceuphorianthigh
Intentional misuse leading to overdose can include using prescribed or unprescribed drugs in excessive quantities in an attempt to produce euphoria.
Occurring in a small percentage of individuals at recommended doses, euphoria is increasingly frequent at supratherapeutic doses (or with intravenous- or nasal administration).

Epileptic seizure

seizureseizuresepileptic seizures
A person experiencing an opioid overdose might also have muscle spasms, seizures and decreased consciousness.
Both medication and drug overdoses can result in seizures, as may certain medication and drug withdrawal.

Opioid overdose

heroin overdoseoverdosedrug overdose
A person experiencing an opioid overdose might also have muscle spasms, seizures and decreased consciousness.
In 2017 opioid deaths represented more than 65% of all drug overdose related deaths in the United States.

Hypnotic

sleeping pillssleeping pillsoporific
Among sedative-hypnotics (F13)
Although the best drug family at the time (less toxic and with fewer side effects) they were dangerous in overdose and tended to cause physical and psychological dependence.

Methaqualone

quaaludesQuaaludeMandrax
Methaqualone
An overdose can cause delirium, convulsions, hypertonia, hyperreflexia, vomiting, kidney failure, coma, and death through cardiac or respiratory arrest.

Paracetamol

acetaminophenparacetamol (acetaminophen)acetaminophen (paracetamol)
Other laboratory test such as glucose, urea and electrolytes, paracetamol levels and salicylate levels are typically done.
Acute overdoses of paracetamol can cause potentially fatal liver damage.

Activated carbon

activated charcoalactive carbonactive charcoal
As a nonspecific antidote, activated charcoal is frequently recommended if available within one hour of the ingestion and the ingestion is significant.
Activated carbon is used to treat poisonings and overdoses following oral ingestion.

Gastric lavage

stomach pumpstomach pumpedstomachs pumped
Gastric lavage, syrup of ipecac, and whole bowel irrigation are rarely used.
Such devices are normally used on a person who has ingested a poison or overdosed on a drug such as alcohol.

Medical toxicology

medical toxicologistsClinical toxicologistsclinical toxicology
Poison control centers and medical toxicologists are available in many areas to provide guidance in overdoses to both physicians and the general public.
Medical toxicologists are involved in the assessment and treatment of a wide variety of problems including acute or chronic poisoning, adverse drug reactions (ADRs), drug overdoses, envenomations, substance abuse, industrial accidents, and other chemical exposures.

Morphine

morphiamorphine addictionmorphine sulfate
For example, naloxone is the antidote for opiates such as heroin or morphine.
A large overdose can cause asphyxia and death by respiratory depression if the person does not receive medical attention immediately.

Responsible drug use

Responsible Drug User's Oathsometimes drugs enter into our life
Responsible drug use
measuring accurate dosages, and take other precautions to reduce the risk of overdose when taking drugs where an overdose is possible

Syrup of ipecac

ipecacipecac syrupoil of ipecac
Gastric lavage, syrup of ipecac, and whole bowel irrigation are rarely used.
Ipecac also presents a small risk of overdose (being a mild poison itself) and a major risk of esophagitis and aspiration pneumonia if used to purge corrosive poisons.

Poly drug use

polydrugpolydrug usein combination
Among poly drug use (F19)
Drug overdose

Benzodiazepine

benzodiazepinesbenzodiazapines1,4-benzodiazepine
Similarly, benzodiazepine overdoses may be effectively reversed with flumazenil.
Taken alone, they rarely cause severe complications in overdose; statistics in England showed that benzodiazepines were responsible for 3.8% of all deaths by poisoning from a single drug.

Toxicology

toxicologisttoxicologicaltoxicologists
Overdose

Ingestion

ingestedconsumptioningest
A drug overdose (or simply overdose or OD) is the ingestion or application of a drug or other substance in quantities greater than are recommended or generally practiced.

Drug

drugsagentserum
A drug overdose (or simply overdose or OD) is the ingestion or application of a drug or other substance in quantities greater than are recommended or generally practiced.