Eosinophilic gastroenteritis

eosinophilic enteritis
Eosinophilic gastroenteritis (EG) is a rare and heterogeneous condition characterized by patchy or diffuse eosinophilic infiltration of gastrointestinal (GI) tissue, first described by Kaijser in 1937.wikipedia
91 Related Articles

Malabsorption

malabsorption syndromeintestinal malabsorptionmalabsorption of nutrients
Mucosal EG (25–100%) is the most common variety, which presents with features of malabsorption and protein losing enteropathy. Failure to thrive and anaemia may also be present. Lower gastrointestinal bleeding may imply colonic involvement.

Abdominal distension

abdominal distentiondistensiondistended
EG typically presents with a combination of chronic nonspecific GI symptoms which include abdominal pain, diarrhea, occasional nausea and vomiting, weight loss and abdominal distension.
Eosinophilic gastroenteritis

Eosinophilia

Eosinophilicpulmonary eosinophiliaan increase of eosinophils in the blood
Peripheral blood eosinophilia and elevated serum IgE are usual but not universal.
Eosinophilic gastroenteritis

Hypereosinophilia

diseases associated with pathologically increased levels of blood eosinophilsabnormally high levels of circulating blood eosinophils
Hypereosinophilia, the hallmark of allergic response, may be absent in up to 20% of patients, but hypoalbuminaemia and other abnormalities suggestive of malabsorption may be present.
Examples of organ-restricted hypereosinopilia include eosinophilic myocarditis, eosinophilic esophagitis, eosinophilic gastroenteritis, eosinophilic cystitis, eosinophilic pneumonia, eosinophilic fasciitis, eosinophilic folliculitis, eosinophilic cellulitis, eosinophilic vasculitis, and eosinophilic ulcer of the oral mucosa.

Eosinophilic esophagitis

inflammation of the esophaguseosinophilic oesophagitis
Eosinophilic esophagitis
Eosinophilic gastroenteritis

Gluten-sensitive enteropathy–associated conditions

Celiac disease epilepsy occipital calcificationsenteropathyGluten-sensitive enteropathy associated T-cell lymphoma
These include bowel disorders (diarrhoea, constipation, irritable bowel), eosinophilic gastroenteritis and increase with coeliac disease (CD) severity.

Irritable bowel syndrome

IBSbowelirritable bowel
Less common causes of this symptom profile are carcinoid syndrome, microscopic colitis, bacterial overgrowth, and eosinophilic gastroenteritis; IBS is, however, a common presentation, and testing for these conditions would yield low numbers of positive results, so it is considered difficult to justify the expense.

Food protein-induced enterocolitis syndrome

Diagnosis is primarily based on history as specific IgE and skin prick tests are typically negative and the exclusion of other disorders that present similar clinical features, such as infectious gastroenteritis, celiac disease, inflammatory bowel disease, and eosinophilic gastroenteritis, among others.

Hookworm infection

hookwormhookworm diseaseankylostomiasis
Deworm pet dogs and cats. Canine and feline hookworms rarely develop to adulthood in humans. Ancylostoma caninum, the common dog hookworm, occasionally develops into an adult to cause eosinophilic enteritis in people, but their invasive larvae can cause an itchy rash called cutaneous larva migrans.

Milk allergy

milk allergiesmilkallergic
The symptoms of milk allergy can be confused with other disorders that present similar clinical features, such as lactose intolerance, infectious gastroenteritis, celiac disease, non-celiac gluten sensitivity, inflammatory bowel disease, eosinophilic gastroenteritis, and pancreatic insufficiency, among others.

FIP1L1

FIP1L1-PDGFRAFIP1L1-PDGFRA'' gene fusionFIP1L1-PDGFRA''-fusion induced hypereosinophelia and leukemia
They may also present with or have a history of signs and/or symptoms that are due to the damaging actions of tissue-infiltrating eosinophils such as: skin rashes or erythema; eosinophilic myocarditis (i.e. heart disease which may manifest as coronary artery disease, heart failure due to injured cardiac muscle, restrictive cardiomyopathy due to cardiac fibrosis, or blockage of arteries due to the embolization of blood clots that from in the heart); pulmonary airway and parenchymal disease; eosinophilic gastroenteritis; eosinophilic esophagitis; and dysfunction of other organs targeted by eosinophils.

Eosinophilic

pink-stainingeosinophilic cellseosinophilic granulocytes
Eosinophilic gastroenteritis (EG) is a rare and heterogeneous condition characterized by patchy or diffuse eosinophilic infiltration of gastrointestinal (GI) tissue, first described by Kaijser in 1937.

Stomach

gastricfunduscardia
The stomach is the organ most commonly affected, followed by the small intestine and the colon.

Organ (anatomy)

organorgansviscera
The stomach is the organ most commonly affected, followed by the small intestine and the colon.

Small intestine

small bowelsmall intestinessmall
The stomach is the organ most commonly affected, followed by the small intestine and the colon.

Large intestine

coloncolorectallarge bowel
The stomach is the organ most commonly affected, followed by the small intestine and the colon.

Abdominal pain

stomach acheupset stomachstomachache
EG typically presents with a combination of chronic nonspecific GI symptoms which include abdominal pain, diarrhea, occasional nausea and vomiting, weight loss and abdominal distension.

Diarrhea

diarrhoeadiarrheal diseaseschronic diarrhea
EG typically presents with a combination of chronic nonspecific GI symptoms which include abdominal pain, diarrhea, occasional nausea and vomiting, weight loss and abdominal distension.

Nausea

nauseousvomitingfeeling of sickness
EG typically presents with a combination of chronic nonspecific GI symptoms which include abdominal pain, diarrhea, occasional nausea and vomiting, weight loss and abdominal distension.

Vomiting

emeticvomitemesis
EG typically presents with a combination of chronic nonspecific GI symptoms which include abdominal pain, diarrhea, occasional nausea and vomiting, weight loss and abdominal distension.

Weight loss

weight-losslose weightlosing weight
EG typically presents with a combination of chronic nonspecific GI symptoms which include abdominal pain, diarrhea, occasional nausea and vomiting, weight loss and abdominal distension.

Protein losing enteropathy

protein-losing enteropathyprotein-losing conditionprotein-losing enteropathic
Mucosal EG (25–100%) is the most common variety, which presents with features of malabsorption and protein losing enteropathy. Failure to thrive and anaemia may also be present. Lower gastrointestinal bleeding may imply colonic involvement.

Anemia

anaemiaanemicanaemic
Mucosal EG (25–100%) is the most common variety, which presents with features of malabsorption and protein losing enteropathy. Failure to thrive and anaemia may also be present. Lower gastrointestinal bleeding may imply colonic involvement.