A report on Ergocalciferol
Type of vitamin D found in food and used as a dietary supplement.
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Vitamin D
7 linksGroup of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and many other biological effects.
Group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and many other biological effects.
In humans, the most important compounds in this group are vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol).
Cholecalciferol
6 linksType of vitamin D that is made by the skin when exposed to sunlight; it is found in some foods and can be taken as a dietary supplement.
Type of vitamin D that is made by the skin when exposed to sunlight; it is found in some foods and can be taken as a dietary supplement.
There are conflicting reports concerning the relative effectiveness of cholecalciferol (D3) versus ergocalciferol (D2), with some studies suggesting less efficacy of D2, and others showing no difference.
Vitamin D deficiency
2 linksVitamin D level that is below normal.
Vitamin D level that is below normal.
Since vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol) are fat-soluble, humans and other animals with a skeleton need to store some fat.
CYP2R1
2 linksCytochrome P450 2R1, an enzyme which is the principal vitamin D 25-hydroxylase.
Cytochrome P450 2R1, an enzyme which is the principal vitamin D 25-hydroxylase.
CYP2R1 will also hydroxylate ergocalciferol (vitamin D2), derived from dietary sources, into 25-hydroxyvitamin D2 (ercalcidiol).
Ergosterol
1 linksSterol found in cell membranes of fungi and protozoa, serving many of the same functions that cholesterol serves in animal cells.
Sterol found in cell membranes of fungi and protozoa, serving many of the same functions that cholesterol serves in animal cells.
In human nutrition, ergosterol is a provitamin form of vitamin D2; exposure to ultraviolet (UV) light causes a chemical reaction that produces vitamin D2.
Calcitriol
2 linksActive form of vitamin D, normally made in the kidney.
Active form of vitamin D, normally made in the kidney.
Compared to other vitamin D compounds in clinical use (cholecalciferol, ergocalciferol), calcitriol has a higher risk of inducing hypercalcemia.
Mushroom
1 linksFleshy, spore-bearing fruiting body of a fungus, typically produced above ground, on soil, or on its food source.
Fleshy, spore-bearing fruiting body of a fungus, typically produced above ground, on soil, or on its food source.
The US Department of Agriculture provided evidence that UV-exposed mushrooms contain substantial amounts of vitamin D. When exposed to ultraviolet (UV) light, even after harvesting, ergosterol in mushrooms is converted to vitamin D2, a process now used intentionally to supply fresh vitamin D mushrooms for the functional food grocery market.
Vitamin D-binding protein
2 linksProtein that in humans is encoded by the GC gene.
Protein that in humans is encoded by the GC gene.
It is able to bind the various forms of vitamin D including ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3), the 25-hydroxylated forms (calcifediol), and the active hormonal product, 1,25-dihydroxyvitamin D (calcitriol).
Steroid
1 linksBiologically active organic compound with four rings arranged in a specific molecular configuration.
Biologically active organic compound with four rings arranged in a specific molecular configuration.
Vitamin D forms such as ergocalciferol, cholecalciferol, and calcitriol
WHO Model List of Essential Medicines
1 linksThe WHO Model List of Essential Medicines (aka Essential Medicines List or EML ), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
The WHO Model List of Essential Medicines (aka Essential Medicines List or EML ), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
Ergocalciferol