Ergocalciferol

vitamin D 2 D2ergocalciferolsVitamin D2DeltalinDrisdolOstelin
Ergocalciferol, also known as vitamin D 2 and calciferol, is a type of vitamin D found in food and used as a dietary supplement.wikipedia
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Vitamin D

DCalciferol1,25 Dihydroxy vitamin D
Ergocalciferol, also known as vitamin D 2 and calciferol, is a type of vitamin D found in food and used as a dietary supplement.
In humans, the most important compounds in this group are vitamin D 3 (also known as cholecalciferol) and vitamin D 2 (ergocalciferol).

Vitamin D deficiency

hypovitaminosis Dvitamin Ddeficiency of vitamin D
As a supplement it is used to prevent and treat vitamin D deficiency.
Since vitamin D 3 (also known as cholecalciferol) and vitamin D 2 (ergocalciferol) are fat-soluble, humans and other animals with a skeleton need to store some fat.

Cholecalciferol

vitamin D 3 vitamin D3colecalciferol
Ergocalciferol may be used as a vitamin D supplement, whereas cholecalciferol (vitamin D 3 ) is produced naturally by the skin when exposed to ultraviolet light.
There are conflicting reports concerning the relative effectiveness of cholecalciferol (D 3 ) versus ergocalciferol (D 2 ), with some studies suggesting less efficacy of D 2, and others showing no difference.

Mushroom

mushroomstoadstoolmacrofungi
Food in which it is found include some mushrooms.
The US Department of Agriculture provided evidence that UV-exposed mushrooms contain substantial amounts of vitamin D. When exposed to ultraviolet (UV) light, even after harvesting, ergosterol in mushrooms is converted to vitamin D 2, a process now used intentionally to supply fresh vitamin D mushrooms for the functional food grocery market.

Ergosterol

viosterolergosteroids
Ergocalciferol is a secosteroid formed by a photochemical bond breaking of a steroid, specifically, by the action of ultraviolet light on ergosterol, a form of provitamin D 2.
In human nutrition, ergosterol is a provitamin form of vitamin D 2 ; exposure to ultraviolet (UV) light causes a chemical reaction that produces vitamin D 2.

Steroid

steroidssteroidogenesisbiosynthesis of steroids
Ergocalciferol is a secosteroid formed by a photochemical bond breaking of a steroid, specifically, by the action of ultraviolet light on ergosterol, a form of provitamin D 2.
* Vitamin D forms such as ergocalciferol, cholecalciferol, and calcitriol

WHO Model List of Essential Medicines

World Health Organization's List of Essential MedicinesList of Essential MedicinesModel List of Essential Medicines
It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.

Vitamin D-binding protein

GCGC (gene)reaction in humans
Ergocalciferol and metabolites have lower affinity to the vitamin D-binding protein compared to the D 3 counterparts.
It is able to bind the various forms of vitamin D including ergocalciferol (vitamin D 2 ) and cholecalciferol (vitamin D 3 ), the 25-hydroxylated forms (calcifediol), and the active hormonal product, 1,25-dihydroxyvitamin D (calcitriol).

Calcitriol

1,25-Dihydroxycholecalciferol1,25 dihydroxyvitamin D 3 1,25-dihydroxyvitamin D 3
The binding affinity of ercalcitriol to the vitamin D receptor is similar to that of calcitriol.
Compared to other vitamin D compounds in clinical use (cholecalciferol, ergocalciferol), calcitriol has a higher risk of inducing hypercalcemia.

Shiitake

shiitake mushroomshiitake mushroomsLentinula edodes
Like all mushrooms, shiitakes produce vitamin D2 upon exposure of their internal ergosterol to ultraviolet B (UVB) rays from sunlight or broadband UVB fluorescent tubes.

Agaricus bisporus

button mushroomchampignonbutton mushrooms
bisporus'' only contains 0.2 micrograms (8 IU) of vitamin D as ergocalciferol (vitamin D2), the ergocalciferol content increases substantially after exposure to UV light.

Dietary supplement

dietary supplementsnutritional supplementnutritional supplements
Ergocalciferol, also known as vitamin D 2 and calciferol, is a type of vitamin D found in food and used as a dietary supplement. Ergocalciferol may be used as a vitamin D supplement, whereas cholecalciferol (vitamin D 3 ) is produced naturally by the skin when exposed to ultraviolet light.

Malabsorption

malabsorption syndromeintestinal malabsorptionmalabsorption of nutrients
This includes vitamin D deficiency due to poor absorption by the intestines or liver disease.

Liver disease

liver problemsliver dysfunctionliver
This includes vitamin D deficiency due to poor absorption by the intestines or liver disease.

Hypocalcaemia

hypocalcemialow blood calciumcalcium deficiency
It may also be used for low blood calcium due to hypoparathyroidism.

Hypoparathyroidism

hypo-Idiopathic hypoparathyroidism
It may also be used for low blood calcium due to hypoparathyroidism.

Intramuscular injection

intramuscularinjection into a muscleinjection into muscle
It is used by mouth or injection into a muscle.

Hypertension

high blood pressurehypertensivearterial hypertension
Excessive doses can result in increased urine production, high blood pressure, kidney stones, kidney failure, weakness, and constipation.

Kidney stone disease

kidney stonekidney stonesnephrolithiasis
Excessive doses can result in increased urine production, high blood pressure, kidney stones, kidney failure, weakness, and constipation.

Kidney failure

renal failurekidney problemsrenal impairment
Excessive doses can result in increased urine production, high blood pressure, kidney stones, kidney failure, weakness, and constipation.

Calcification

calcifieduncalcifiedcalcifying
If high doses are taken for a long period of time, tissue calcification may occur.

Pregnancy

pregnantfirst trimesterpregnant women
Normal doses are safe in pregnancy.

Calcium

CaCa 2+ calcium ions
It works by increasing the amount of calcium absorbed by the intestines and kidneys.

Health system

health care systemhealthcare systemhealth systems
It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.

Generic drug

generic medicationgenericgeneric drugs
Ergocalciferol is available as a generic medication and over the counter.