A report on Esophagus and Esophageal achalasia

The digestive tract, with the esophagus marked in red
A chest X-ray showing achalasia ( arrows point to the outline of the massively dilated esophagus )
The esophagus is constricted in three places.
Transhiatal oesophagectomy specimen from a patient suffering from late-stage achalasia. Diverticulum at the left lower end of the oesophagus.
A mass seen during an endoscopy and an ultrasound of the mass conducted during the endoscopy session.
An axial CT image showing marked dilatation of the esophagus in a person with achalasia.
"Bird's beak" appearance and "megaesophagus", typical in achalasia.
Schematic of manometry in achalasia showing aperistaltic contractions, increased intraesophageal pressure, and failure of relaxation of the lower esophageal sphincter.
Image of a stomach which has undergone Fundoplomy

Esophageal achalasia, often referred to simply as achalasia, is a failure of smooth muscle fibers to relax, which can cause the lower esophageal sphincter to remain closed.

- Esophageal achalasia

Achalasia refers to a failure of the lower esophageal sphincter to relax properly, and generally develops later in life.

- Esophagus
The digestive tract, with the esophagus marked in red

9 related topics with Alpha

Overall

Endoscopic image of an esophageal adenocarcinoma

Esophageal cancer

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Endoscopic image of an esophageal adenocarcinoma
Esophageal cancer (lower part) as a result of Barrettʼs esophagus
Esophageal cancer as shown by a filling defect during an upper GI series
Esophageal stent for esophageal cancer
Esophageal stent for esophageal cancer
Before and after a total esophagectomy
Typical scar lines after the two main methods of surgery
Death from esophageal cancer per million persons in 2012
Endoscopic image of Barrett esophagus – a frequent precursor of esophageal adenocarcinoma
Endoscopy and radial endoscopic ultrasound images of a submucosal tumor in the central portion of the esophagus
Contrast CT scan showing an esophageal tumor (axial view)
Contrast CT scan showing an esophageal tumor (coronal view)
Esophageal cancer
Micrograph showing histopathological appearance of an esophageal adenocarcinoma (dark blue – upper-left of image) and normal squamous epithelium (upper-right of image) at H&E staining
T1, T2, and T3 stages of esophageal cancer
Stage T4 esophageal cancer
Esophageal cancer with spread to lymph nodes
Internal radiotherapy for esophageal cancer
Self-expandable metallic stents are sometimes used for palliative care

Esophageal cancer is cancer arising from the esophagus—the food pipe that runs between the throat and the stomach.

Achalasia (i.e. lack of the involuntary reflex in the esophagus after swallowing) appears to be a risk factor for both main types of esophageal cancer, at least in men, due to stagnation of trapped food and drink.

The digestive tract, with the esophagus marked in red

Dysphagia

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Difficulty in swallowing.

Difficulty in swallowing.

The digestive tract, with the esophagus marked in red

Achalasia is a major exception to usual pattern of dysphagia in that swallowing of fluid tends to cause more difficulty than swallowing solids.

In achalasia, there is idiopathic destruction of parasympathetic ganglia of the Auerbach's (Myenteric) plexus of the entire esophagus, which results in functional narrowing of the lower esophagus, and peristaltic failure throughout its length.

Potential location of pain from a heart attack

Chest pain

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Pain or discomfort in the chest, typically the front of the chest.

Pain or discomfort in the chest, typically the front of the chest.

Potential location of pain from a heart attack
A blockage of coronary arteries can lead to a heart attack
Gastroesophageal reflux disease is a common cause of chest pain in adults

Achalasia, nutcracker esophagus, and other motility disorders of the esophagus

Surgical removal of the esophagus.

Esophagectomy

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Surgical removal of the esophagus.
Diagram showing before and after an oesophago-gastrectomy
Diagram showing before and after a partial oesophagectomy
Diagram showing before and after a total oesophagectomy
An esophagectomy using the bowel (colon) to replace the esophagus

Esophagectomy or oesophagectomy is the surgical removal of all or parts of the esophagus.

Esophagectomy is also occasionally performed for benign disease such as esophageal atresia in children, achalasia, or caustic injury.

Normal peristalsis in time space graph. Nutcracker esophagus shows higher amplitude contractions (Z-axis) that take longer to pass (X-axis)

Nutcracker esophagus

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Normal peristalsis in time space graph. Nutcracker esophagus shows higher amplitude contractions (Z-axis) that take longer to pass (X-axis)
Diagram of esophageal motility study in nutcracker esophagus: The disorder shows peristalsis with high-pressure esophageal contractions exceeding 180 mmHg and contractile waves with a long duration exceeding 6 sec.
Normal esophagus in (A). Nutcracker esophagus in (C): high-pressure waves in blue; cross-sectional areas (CSA) in fucsia.

Nutcracker esophagus, Jackhammer esophagus, or hypercontractile peristalsis, is a disorder of the movement of the esophagus characterized by contractions in the smooth muscle of the esophagus in a normal sequence but at an excessive amplitude or duration.

Nutcracker esophagus is one of several motility disorders of the esophagus, including achalasia and diffuse esophageal spasm.

Barium meal examination showing the stomach and duodenum in double contrast technique with CO2 as negative contrast medium

Upper gastrointestinal series

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Series of radiographs used to examine the gastrointestinal tract for abnormalities.

Series of radiographs used to examine the gastrointestinal tract for abnormalities.

Barium meal examination showing the stomach and duodenum in double contrast technique with CO2 as negative contrast medium
Barium follow through showing the small bowel
Enteroclysis in double contrast technique showing stenosis of the small intestine
Zenker's diverticulum as seen in a barium swallow examination
Barium in the lungs resulting from aspiration during a barium swallow

This in combination with other plain radiographs allows for the imaging of parts of the upper gastrointestinal tract such as the pharynx, larynx, esophagus, stomach, and small intestine such that the inside wall lining, size, shape, contour, and patency are visible to the examiner.

Amongst the uses of barium swallow are: persistent dysphagia and odynophagia despite negative esophagogastroduodenoscopy (OGDS) findings, failed OGDS, esophageal motility disorder, globus pharyngis, assessment of tracheoesophageal fistula, and timed barium swallow to monitor the progress of esophageal achalasia therapy.

Chagas megaseophagus

Megaesophagus

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Chagas megaseophagus
An x-ray of the thorax of a dog with megaoesophagus. The edges of the esophagus are shown by the yellow arrows. (In this image, the head end of the dog is to the right, and the tail end is to the left
The apparatus for management of the dog's megaesophagus can be simply made from a regular chair turned upside down. Some soft material to protect the back and chest of the dog may be used.

Megaesophagus, also known as esophageal dilatation, is a disorder of the esophagus in humans and other mammals, whereby the esophagus becomes abnormally enlarged.

Megaesophagus may occur secondary to diseases such as achalasia or Chagas disease.

A time-space diagram of a peristaltic wave after a water swallow. High-pressure values are red, zero pressure is blue-green. The ridge in the upper part of the picture is the high pressure of the upper esophageal sphincter which only opens for a short time to let water pass.

Peristalsis

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Radially symmetrical contraction and relaxation of muscles that propagates in a wave down a tube, in an anterograde direction.

Radially symmetrical contraction and relaxation of muscles that propagates in a wave down a tube, in an anterograde direction.

A time-space diagram of a peristaltic wave after a water swallow. High-pressure values are red, zero pressure is blue-green. The ridge in the upper part of the picture is the high pressure of the upper esophageal sphincter which only opens for a short time to let water pass.
A simplified image showing peristalsis
A simplified image showing Earthworm movement via peristalsis

When a peristaltic wave reaches at the end of the esophagus, the cardiac sphincter (gastroesophageal sphincter) opens allowing the passage of bolus into the stomach.

Aperistalsis refers to a lack of propulsion. It can result from achalasia of the smooth muscle involved.

Diagram of a Nissen fundoplication.

Nissen fundoplication

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Surgical procedure to treat gastroesophageal reflux disease and hiatal hernia.

Surgical procedure to treat gastroesophageal reflux disease and hiatal hernia.

Diagram of a Nissen fundoplication.
A completed Nissen fundoplication

In a fundoplication, the gastric fundus (upper part) of the stomach is wrapped, or plicated, around the lower end of the esophagus and stitched in place, reinforcing the closing function of the lower esophageal sphincter (LES).

In contrast, surgery for achalasia is generally accompanied by either a Dor or Toupet partial fundoplication, which is less likely than a Nissen wrap to aggravate the dysphagia that characterizes achalasia.