Gangrene

gangrenousfesteringdry gangrene gangrenousbowel tissue has dieddry and wet gangrenefestersfoot gangreneGangraena universalisgangrene infection
Gangrene is a type of tissue death caused by a lack of blood supply.wikipedia
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Necrosis

necroticnecrotizingnecrotic tissue
Gangrene is a type of tissue death caused by a lack of blood supply.
A classic example is gangrene.

Ischemia

ischemicischaemiaischaemic
Gangrene is a type of tissue death caused by a lack of blood supply.
Without immediate intervention, ischemia may progress quickly to tissue necrosis and gangrene within a few hours.

Raynaud syndrome

Raynaud's diseaseRaynaud's phenomenonRaynaud phenomena
Risk factors include diabetes, peripheral arterial disease, smoking, major trauma, alcoholism, HIV/AIDS, frostbite, and Raynaud's syndrome.
Severe disease may rarely be complicated by skin sores or gangrene.

Gas gangrene

myonecrosisclostridial myonecrosisclostridial myositis
It can be classified as dry gangrene, wet gangrene, gas gangrene, internal gangrene, and necrotizing fasciitis.
Gas gangrene (also known as clostridial myonecrosis and myonecrosis ) is a bacterial infection that produces gas in tissues in gangrene.

Peripheral artery disease

peripheral vascular diseaseperipheral arterial diseasearterial insufficiency
Risk factors include diabetes, peripheral arterial disease, smoking, major trauma, alcoholism, HIV/AIDS, frostbite, and Raynaud's syndrome.
Complications may include an infection or tissue death which may require amputation; coronary artery disease, or stroke.

Amputation

amputatedamputeeamputate
Surgical efforts may include debridement, amputation, or the use of maggot therapy.
As a surgical measure, it is used to control pain or a disease process in the affected limb, such as malignancy or gangrene.

Frostbite

frostbittenfrost bitecold burn
Risk factors include diabetes, peripheral arterial disease, smoking, major trauma, alcoholism, HIV/AIDS, frostbite, and Raynaud's syndrome.
Debridement or amputation of necrotic tissue is usually delayed unless there is gangrene or systemic infection (sepsis).

Fournier gangrene

Fournier's gangrene
Fournier gangrene is a type of necrotizing fasciitis that usually affects the genitals and groin.
Fournier gangrene is a type of necrotizing fasciitis or gangrene affecting the external genitalia and/or perineum.

Autoamputation

digital autoamputation
The line of separation usually brings about complete separation, with eventual falling off of the gangrenous tissue if it is not removed surgically, a process called autoamputation.
Once the vessels are destroyed, the tissue is starved of oxygen and dies, which is often followed by gangrene.

Arterial insufficiency ulcer

Arterial ulcersarterialarterial insufficiency ulcers
If ischemia is detected early, when ischemic wounds rather than gangrene are present, the process can be treated by revascularization (via vascular bypass or angioplasty).
Gangrene

Ischemic colitis

colitis, ischemicintestinal ischemiaIschemic bowel
Severe ischemic colitis may result in gangrene of the large intestine.
Those with severe ischemia who develop complications such as sepsis, intestinal gangrene, or bowel perforation may require more aggressive interventions such as surgery and intensive care.

Critical limb ischemia

tissue losscritical limb ischaemiaischemic limb
In the case of gangrene due to critical limb ischemia, revascularization can be performed to treat the underlying peripheral artery disease.
It is defined as a triad of ischemic rest pain, arterial insufficiency ulcers, and gangrene.

Necrotizing fasciitis

necrotising fasciitisflesh-eating bacteriaflesh-eating virus
It can be classified as dry gangrene, wet gangrene, gas gangrene, internal gangrene, and necrotizing fasciitis.
Gangrene

Revascularization

revascularisationre-vascularisationrevascularized
If ischemia is detected early, when ischemic wounds rather than gangrene are present, the process can be treated by revascularization (via vascular bypass or angioplasty).
Treatment for gangrene often requires revascularization, if possible.

Peter DeMarco

therapeutic chemicals
A regenerative medicine therapy was developed by Dr. Peter DeMarco to treat diabetic gangrene to avoid amputations.
Pharmaceutical company Johnson & Johnson's Ortho Research Laboratory wrote that case histories of his therapy, "were quite remarkable and your concepts most intriguing" and ICN Pharmaceuticals replied, "The results you have obtained with this drug in the treatment of gangrene have been most spectacular", but DeMarco was never able to commercialize the therapy beyond his own medical practice.

Chronic wound

chronic woundsdiabetic ulcerchronic
Growth factors, hormones, and skin grafts have also been used to accelerate healing for gangrene and other chronic wounds.
Infection can lead not only to chronic wounds but also to gangrene, loss of the infected limb, and death of the patient.

Jean-Baptiste Lully

LullyJean Baptiste LullyLully, Jean-Baptiste
The French Baroque composer Jean-Baptiste Lully contracted gangrene in January 1687 when, while conducting a performance of his Te Deum, he stabbed his own toe with his pointed staff (which was used as a baton).
Lully died from gangrene, having struck his foot with his long conducting staff during a performance of his Te Deum to celebrate Louis XIV's recovery from surgery.

Guillotine amputation

Because of the high mortality associated with infected gangrene, an emergency salvage amputation, such as a guillotine amputation, is often needed to limit systemic effects of the infection.
Typical indications include catastrophic trauma or infection control in the setting of infected gangrene.

Ulcer (dermatology)

ulcerulcersulceration
As early as 1028, flies and maggots were commonly used to treat chronic wounds or ulcers to prevent or arrest necrotic spread, as some species of maggots consume only dead flesh, leaving nearby living tissue unaffected.

Mesenteric ischemia

intestinal ischemiaischemic bowelmesenteric vascular occlusion
Severe mesenteric ischemia may result in gangrene of the small intestine.
If the ischemia has progressed to the point that the affected intestinal segments are gangrenous, a bowel resection of those segments is called for.

Baton (conducting)

batonbatonsconductor's baton
The French Baroque composer Jean-Baptiste Lully contracted gangrene in January 1687 when, while conducting a performance of his Te Deum, he stabbed his own toe with his pointed staff (which was used as a baton).
The wound turned gangrenous, but Lully refused to have his toe amputated and the infection spread, resulting in his death on 22 March.

Louis XIV of France

Louis XIVKing Louis XIVKing Louis XIV’s
French King Louis XIV died of gangrene in his leg on 1 September 1715, four days prior to his 77th birthday.
The 2016 film The Death of Louis XIV, directed by Albert Serra, is set during the last two weeks of Louis XIV's life before dying of gangrene, with the monarch played by Jean-Pierre Léaud.

Surgery

surgicalsurgeonsurgical procedure
Pasteur suggested three methods to eliminate the micro-organisms responsible for gangrene: filtration, exposure to heat, or exposure to chemical solutions.

Fever

febrilepyrexiaague
Certain types may present with a fever or sepsis.

Sepsis

septicemiasepticaemiablood poisoning
Certain types may present with a fever or sepsis.