Glucose-1,6-bisphosphate synthase

Glucose-1,6-bisphosphate synthase is a type of enzyme called a phosphotransferase and is involved in mammalian starch and sucrose metabolism (KEGG, 2.7.1.106).wikipedia
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Glucose 1,6-bisphosphate

glucose-1,6-bisphosphate
It catalyzes the transfer of a phosphate group from 1,3-bisphosphoglycerate to glucose-1-phosphate, yielding 3-phosphoglycerate and glucose-1,6-bisphosphate.

Phosphotransferase

phosphotransferase enzymesphosphotransferasesphosphotransfer
Glucose-1,6-bisphosphate synthase is a type of enzyme called a phosphotransferase and is involved in mammalian starch and sucrose metabolism (KEGG, 2.7.1.106).

Phosphate

phosphatesphosphate groupinorganic phosphate
It catalyzes the transfer of a phosphate group from 1,3-bisphosphoglycerate to glucose-1-phosphate, yielding 3-phosphoglycerate and glucose-1,6-bisphosphate.

1,3-Bisphosphoglyceric acid

1,3-bisphosphoglycerate3-phospho-D-glyceroyl phosphate1,3-bisphospho-D-glycerate
It catalyzes the transfer of a phosphate group from 1,3-bisphosphoglycerate to glucose-1-phosphate, yielding 3-phosphoglycerate and glucose-1,6-bisphosphate.

Glucose 1-phosphate

glucose-1-phosphatebeta-D-glucose 1-phosphateCori ester
It catalyzes the transfer of a phosphate group from 1,3-bisphosphoglycerate to glucose-1-phosphate, yielding 3-phosphoglycerate and glucose-1,6-bisphosphate.

3-Phosphoglyceric acid

3-phosphoglycerate3-phospho-D-glycerateglycerate 3-phosphate
It catalyzes the transfer of a phosphate group from 1,3-bisphosphoglycerate to glucose-1-phosphate, yielding 3-phosphoglycerate and glucose-1,6-bisphosphate.

Zinc

ZnZn 2+ zinc alloy
Zinc (Zn 2+ ), Magnesium (Mg 2+ ), Manganese (Mn 2+ ), Calcium (Ca 2+ ), Nickel (Ni 2+ ), Copper (Cu 2+ ), Cadmium (Cd 2+ ) are all proven effective cofactors in vitro.

Magnesium

MgMg 2+ Mg2+
Zinc (Zn 2+ ), Magnesium (Mg 2+ ), Manganese (Mn 2+ ), Calcium (Ca 2+ ), Nickel (Ni 2+ ), Copper (Cu 2+ ), Cadmium (Cd 2+ ) are all proven effective cofactors in vitro.

Manganese

Mnmanganese oreMn 2+
Zinc (Zn 2+ ), Magnesium (Mg 2+ ), Manganese (Mn 2+ ), Calcium (Ca 2+ ), Nickel (Ni 2+ ), Copper (Cu 2+ ), Cadmium (Cd 2+ ) are all proven effective cofactors in vitro.

Calcium

CaCa 2+ calcium ions
Zinc (Zn 2+ ), Magnesium (Mg 2+ ), Manganese (Mn 2+ ), Calcium (Ca 2+ ), Nickel (Ni 2+ ), Copper (Cu 2+ ), Cadmium (Cd 2+ ) are all proven effective cofactors in vitro.

Nickel

NiNi 2+ Nickel (Ni)
Zinc (Zn 2+ ), Magnesium (Mg 2+ ), Manganese (Mn 2+ ), Calcium (Ca 2+ ), Nickel (Ni 2+ ), Copper (Cu 2+ ), Cadmium (Cd 2+ ) are all proven effective cofactors in vitro.

Copper

CuCu 2+ cupric
Zinc (Zn 2+ ), Magnesium (Mg 2+ ), Manganese (Mn 2+ ), Calcium (Ca 2+ ), Nickel (Ni 2+ ), Copper (Cu 2+ ), Cadmium (Cd 2+ ) are all proven effective cofactors in vitro.

Cadmium

CdCd 2+ cadmium compounds
Zinc (Zn 2+ ), Magnesium (Mg 2+ ), Manganese (Mn 2+ ), Calcium (Ca 2+ ), Nickel (Ni 2+ ), Copper (Cu 2+ ), Cadmium (Cd 2+ ) are all proven effective cofactors in vitro.

Hexokinase

Hexokinase IVhexokinase-2
1. Inhibition of hexokinase, an enzyme used in the first step of glycolysis.

Phosphofructokinase 1

phosphofructokinase-1PFK-1PFK1
2. Activation of phosphofructokinase-1 (PFK-1) and pyruvate kinase, both of which are enzymes involved in activation of the glycolytic pathway.

Pyruvate kinase

2. Activation of phosphofructokinase-1 (PFK-1) and pyruvate kinase, both of which are enzymes involved in activation of the glycolytic pathway.

Phosphoglucomutase

EC 5.4.2.2EC 5.4.2.3Phosphoglucomutase deficiency
3. It acts as a coenzyme for phosphoglucomutase in glycolysis and gluconeogenesis.

Glycolysis

glycolyticglycolytic pathwayEmbden–Meyerhof pathway
3. It acts as a coenzyme for phosphoglucomutase in glycolysis and gluconeogenesis.

Gluconeogenesis

gluconeogenicgluconeogenic pathwayglucogenic
3. It acts as a coenzyme for phosphoglucomutase in glycolysis and gluconeogenesis.

Ribose 5-phosphate

D-ribose 5-phosphateribose-5-phosphateribose phosphate
4. It acts as a cofactor for phosphopentomutase, which produces D-ribose-5-phosphate.

Skeletal muscle

skeletal musclesskeletalmuscle
6. It increases in concentration during skeletal muscle contraction.

Glucose 6-phosphate

glucose-6-phosphateG6PD-glucose 6-phosphate
7. Its dephosphorylation yields glucose-6-phosphate, which is an important precursor molecule in glycolysis and the pentose phosphate pathway.

Pentose phosphate pathway

pentose phosphate shunthexose monophosphate shuntpentose phosphate pathway (PPP)
7. Its dephosphorylation yields glucose-6-phosphate, which is an important precursor molecule in glycolysis and the pentose phosphate pathway.

Glucose

dextroseD-glucose D -glucose
Glucose-1,6-bisphosphate inhibit hexokinase stopping the production glucose-6-phosphate from D-glucose.

Fructose 1,6-bisphosphate

fructose-1,6-bisphosphateFructose 1,6-diphosphateF1,6BP
Glucose-1,6-bisphosphate synthase is allosterically inhibited by inorganic phosphate, fructose-1,6-bisphosphate, 3-phosphoglycerate (a product), citrate, lithium, phosphoenolpyruvate (PEP), and acetyl CoA.