HLA-B

Bhla-b antigensHLA-B*5701
HLA-B (major histocompatibility complex, class I, B) is a human gene that provides instructions for making a protein that plays a critical role in the immune system.wikipedia
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HLA-B*83

B*83
HLA-B*83 (B83) is an HLA-B allele-group composed of a single allele, B*8301.

HLA-B40

B40
HLA-B40 (B40) is an HLA - B serotype.

HLA-B60

B60
HLA-B60 (B60) is an HLA - B serotype.

HLA-B61

B61
HLA-B61 (B61) is an HLA - B serotype.

HCP5

*HCP5
This variation of HCP5 frequently occurs in conjunction with a particular version of an immune system gene called HLA-B.

Human

humanshuman beinghuman beings
HLA-B (major histocompatibility complex, class I, B) is a human gene that provides instructions for making a protein that plays a critical role in the immune system.

Gene

genesnumber of genesgene sequence
HLA-B (major histocompatibility complex, class I, B) is a human gene that provides instructions for making a protein that plays a critical role in the immune system.

Protein

proteinsproteinaceousstructural proteins
HLA-B (major histocompatibility complex, class I, B) is a human gene that provides instructions for making a protein that plays a critical role in the immune system.

Immune system

immuneimmune responseimmune function
HLA-B (major histocompatibility complex, class I, B) is a human gene that provides instructions for making a protein that plays a critical role in the immune system.

Virus

virusesviralvirion
The HLA complex helps the immune system distinguish the body's own proteins from proteins made by foreign invaders such as viruses and bacteria.

Bacteria

bacteriumbacterialEubacteria
The HLA complex helps the immune system distinguish the body's own proteins from proteins made by foreign invaders such as viruses and bacteria.

MHC class II

MHC IIclass IIHLA class II
Genes in this complex are separated into three basic groups: class I, class II, and class III.

HLA-C

Chla-c antigensHLA-C554
In humans, the HLA-B gene and two related genes, HLA-A and HLA-C, are the major genes in MHC class I.

Peptide

polypeptidepeptidespolypeptides
On the cell surface, these proteins are bound to protein fragments (peptides) that have been exported from within the cell.

Chromosome 6

chr.66Chromosome 6 (human)
The HLA-B gene is located on the short (p) arm of chromosome 6 at cytoband 21.3, from base pair 31,353,871 to 31,357,211

Base pair

base pairsbpMbp
The HLA-B gene is located on the short (p) arm of chromosome 6 at cytoband 21.3, from base pair 31,353,871 to 31,357,211

Ankylosing spondylitis

Bekhterev’s DiseaseBekhterev's Diseasespondylitis, ankylosing
Ankylosing spondylitis: A version of the HLA-B gene called HLA-B27 increases the risk of developing ankylosing spondylitis.

Spondyloarthropathy

spondyloarthropathiesspondyloarthritisspondylarthritis
HLA-B27 is associated with the spondyloarthropathies, a group of disorders that includes ankylosing spondylitis and other inflammatory joint diseases.

Psoriasis

plaque psoriasispsoriasis vulgarispsoriatic
Some of these diseases are associated with a common skin condition called psoriasis or chronic inflammatory bowel disorders (Crohn's disease and ulcerative colitis).

Crohn's disease

Crohn’s diseaseCrohn diseaseCrohn
Some of these diseases are associated with a common skin condition called psoriasis or chronic inflammatory bowel disorders (Crohn's disease and ulcerative colitis).

Ulcerative colitis

colitis ulcerosaColitisinflammatory colitis
Some of these diseases are associated with a common skin condition called psoriasis or chronic inflammatory bowel disorders (Crohn's disease and ulcerative colitis).

Reactive arthritis

arthritis, reactiveReactive arthropathyreiter disease
One of the spondyloarthropathies, reactive arthritis, is typically triggered by bacterial infections of the gastrointestinal or genital tract.

Han Chinese

HanChineseHan people
For example, two specific versions of this gene are related to increased drug sensitivity among the Han Chinese population.

Carbamazepine

TegretolEpitolAtretol
Individuals who have HLA-B*1502 are more likely to experience a severe skin disorder called Stevens–Johnson syndrome in response to carbamazepine (a drug used to treat seizures).

Allopurinol

AloprimLopurinZyloprim
Another version, HLA-B*5801, is associated with an increased risk of severe skin reactions in people treated with allopurinol (a drug used to treat gout, which is a form of arthritis caused by uric acid in the joints).