Immunological memory

immunological
Immunological memory is the ability of the immune system to quickly and specifically recognize an antigen that the body has previously encountered and initiate a corresponding immune response.wikipedia
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Immune system

immuneimmune responseimmune responses
Immunological memory is the ability of the immune system to quickly and specifically recognize an antigen that the body has previously encountered and initiate a corresponding immune response.
Adaptive (or acquired) immunity creates immunological memory after an initial response to a specific pathogen, leading to an enhanced response to subsequent encounters with that same pathogen.

Immunization

immunisationimmunizationsimmunize
Both populations of these memory cells originate from naive T cells and remain in the body for several years after initial immunization.
When this system is exposed to molecules that are foreign to the body, called non-self, it will orchestrate an immune response, and it will also develop the ability to quickly respond to a subsequent encounter because of immunological memory.

Antigen

antigensantigenicantigenic proteins
Immunological memory is the ability of the immune system to quickly and specifically recognize an antigen that the body has previously encountered and initiate a corresponding immune response.

Immune response

immunological responseimmuneadaptative immune response
Immunological memory is the ability of the immune system to quickly and specifically recognize an antigen that the body has previously encountered and initiate a corresponding immune response.

Memory T cell

memory T cellsmemory Tmemory T lymphocytes
Immunological memory is responsible for the adaptive component of the immune system, special T and B cells — the so-called memory T and B cells.

Memory B cell

memory B cellsmemory cellsmemory cell
Immunological memory is responsible for the adaptive component of the immune system, special T and B cells — the so-called memory T and B cells.

Vaccination

vaccinationsvaccinatedvaccinating
Immunological memory is the basis of vaccination.

MHC class II

class IIHLA class IIMHC II
After the memory B cell recognizes the antigen it presents the peptide: MHC II complex to nearby effector T cells.

Effector cell

effector
After the primary immune response has disappeared the effector cells of the immune response are eliminated.

Antibody

antibodiesimmunoglobulinimmunoglobulins
However, there remain antibodies previously created in the body that represent the humoral component of immunological memory and comprise an important defensive mechanism in subsequent infections.

Humoral immunity

humoralhumoral immune responsehumoral response
However, there remain antibodies previously created in the body that represent the humoral component of immunological memory and comprise an important defensive mechanism in subsequent infections.

Plasma cell

plasma cellsplasmablastplasma B cell
Memory B cells are plasma cells that are able to produce antibodies for a long time.

Affinity maturation

affinity maturedaffinity-matured
The memory B cell has already undergone clonal expansion and differentiation and affinity maturation, so it is able to divide multiple times faster and produce antibodies with much higher affinity (especially IgG).

Cell division

divisiondaughter cellcellular division
The memory B cell has already undergone clonal expansion and differentiation and affinity maturation, so it is able to divide multiple times faster and produce antibodies with much higher affinity (especially IgG).

Immunoglobulin G

IgGIgG1IgG4
The memory B cell has already undergone clonal expansion and differentiation and affinity maturation, so it is able to divide multiple times faster and produce antibodies with much higher affinity (especially IgG).

Lymphatic system

lymphoidlymphoid tissuelymphatic
Memory B cell activity in secondary lymphatic organs is highest during the first 2 weeks after infection.

Germinal center

germinal centregerminal centersgerminal centres
After the germinal center reaction the memory plasma cells are located in the bone marrow which is the main site of antibody production within the immunological memory.

Bone marrow

marrowred bone marrowbone marrow stroma
After the germinal center reaction the memory plasma cells are located in the bone marrow which is the main site of antibody production within the immunological memory.

CD4

CD4+CD4 + antigens, cd4
Memory T cells can be both CD4+ and CD8+.

Cytotoxic T cell

cytotoxic T cellscytotoxic T lymphocytecytotoxic T lymphocytes
Memory T cells can be both CD4+ and CD8+.

Gene expression

expressionexpressedexpress
Memory T cells can be divided into two functionally distinct groups based on the expression of the CCR7 chemokine receptor.

C-C chemokine receptor type 7

CCR7c-c chemokine receptor 7 (CCR7)CCR7 chemokine receptor
Memory T cells can be divided into two functionally distinct groups based on the expression of the CCR7 chemokine receptor.

Inflammation

inflammatoryinflammatory responseinflamed
Those memory T cells that do not express CCR7 (these are CCR7-) have receptors to migrate to the site of inflammation in the tissue and represent an immediate effector cell population.

Interferon gamma

IFN-γinterferon-gammainterferon-γ
After repeated stimulation they produce large amounts of IFN-γ, IL-4 and IL-5.

Interleukin 4

IL-4interleukin-4IL4
After repeated stimulation they produce large amounts of IFN-γ, IL-4 and IL-5.