inflammatoryinflammatory responseinflamedinflammatory diseasesinflammatory diseaseproinflammatoryinflammatory mediatorsinflammatory disordersinflammatory reactionpro-inflammatory
Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.wikipedia
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infectious diseaseinfectious diseasesinfections
Inflammation is not a synonym for infection.
Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response.


inflammation in the urethrainflammation of the penile urethrainflammation of the urethra
For example, the word urethritis strictly means only "urethral inflammation", but clinical health care providers usually discuss urethritis as a urethral infection because urethral microbial invasion is the most common cause of urethritis.
Urethritis is inflammation of the urethra.

Functio laesa

loss of function
The five classical signs of inflammation are heat, pain, redness, swelling, and loss of function (Latin calor, dolor, rubor, tumor, and functio laesa).
It was identified as the fifth sign of acute inflammation by Galen, who added it to the four signs identified by Celsus (tumor, rubor, calor, and dolor).


acute appendicitisruptured appendixburst appendix
Appendicitis is inflammation of the appendix.

Immune system

immuneimmune responseimmune function
A series of biochemical events propagates and matures the inflammatory response, involving the local vascular system, the immune system, and various cells within the injured tissue.
Disorders of the immune system can result in autoimmune diseases, inflammatory diseases and cancer.


eczemaallergic dermatitischronic eczema
Dermatitis, also known as eczema, is a group of diseases that result in inflammation of the skin.


Bursitis is the inflammation of one or more bursae (small sacs) of synovial fluid in the body.


brain inflammationAcute encephalitis syndromeinflammation of the brain
Encephalitis is inflammation of the brain.


spinal meningitisbacterial meningitiscerebral meningitis
Meningitis is an acute inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges.


gingival inflammationgum diseasebleeding
Gingivitis is a non-destructive disease that causes inflammation of the gums.


inflammationspinal cordspinal myelitis
Myelitis is inflammation of the spinal cord which can disrupt the normal responses from the brain to the rest of the body, and from the rest of the body to the brain.


inflammation of the pancreasgallstone pancreatitispancreatic inflammation
Pancreatitis is a condition characterized by inflammation of the pancreas.


throat infectionsore throatthroat infections
Pharyngitis is inflammation of the back of the throat, known as the pharynx.


nephritis, hereditaryAthletic nephritisinflammation of the kidney
Nephritis is inflammation of the kidneys and may involve the glomeruli, tubules, or interstitial tissue surrounding the glomeruli and tubules.

Innate immune system

innate immunityinnateinnate immune response
Inflammation is a generic response, and therefore it is considered as a mechanism of innate immunity, as compared to adaptive immunity, which is specific for each pathogen.
Inflammation is one of the first responses of the immune system to infection or irritation.


coryzaseasonal allergic rhinitisrhinitis, allergic, perennial
Rhinitis, also known as coryza, is irritation and inflammation of the mucous membrane inside the nose.


sinus infectionrhinosinusitischronic sinusitis
Sinusitis, also known as rhinosinusitis, is inflammation of the mucous membranes that line the sinuses resulting in symptoms.


polyneuritisanti-neuriticbrachial neuritis
Neuritis is inflammation of a nerve or the general inflammation of the peripheral nervous system.


tonsilitisVincent's anginaChronic tonsillitis
Tonsillitis is inflammation of the tonsils, typically of rapid onset.


bacterial prostatitisInflammatory diseases of prostateinflammation of the prostate
Prostatitis is inflammation of the prostate gland.

Type III hypersensitivity

type IIItype III hypersensitivity reactionType 3 hypersensitivity
It is useful to differentiate inflammation and infection because there are typical situations in pathology and medical diagnosis where inflammation is not driven by microbial invasion – for example, atherosclerosis, trauma, ischemia, and autoimmune diseases including type III hypersensitivity.
Type III hypersensitivity occurs when there is accumulation of immune complexes (antigen-antibody complexes) that have not been adequately cleared by innate immune cells, giving rise to an inflammatory response and attraction of leukocytes.


vasculitidesvasculiticvasculitis, central nervous system
Vasculitis is a group of disorders that destroy blood vessels by inflammation.


damage to the veinPhlebitis of portal vein
Phlebitis or venitis is the inflammation of a vein, usually in the legs.


bronchopneumoniabronchial pneumoniaNecrotizing pneumonia
Acute inflammation of the lung (usually caused in response to pneumonia) does not cause pain unless the inflammation involves the parietal pleura, which does have pain-sensitive nerve endings.
Pneumonia is an inflammatory condition of the lung affecting primarily the small air sacs known as alveoli.

Mononuclear cell infiltration

inflammatory infiltratemononuclear cells
Prolonged inflammation, known as chronic inflammation, leads to a progressive shift in the type of cells present at the site of inflammation, such as mononuclear cells, and is characterized by simultaneous destruction and healing of the tissue from the inflammatory process.
Mononuclear cell infiltrates are characteristic of inflammatory lesions, where white blood cells, mainly macrophages and lymphocytes, collect at the site of injury to help clear away the debris.