Inflammatory bowel disease

inflammatory bowel diseasesIBDindeterminate colitisbowel disorderBowel inflammationbowelsdigestiveI'''nflammatory bowel diseaseIBD ( inflammatory bowel disease)inflammation of the bowel
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.wikipedia
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Crohn's disease

Crohn’s diseaseCrohn diseaseCrohn
Crohn's disease and ulcerative colitis are the principal types of inflammatory bowel disease. Conditions with similar symptoms as Crohn's disease includes intestinal tuberculosis, Behçet's disease, ulcerative colitis, nonsteroidal anti-inflammatory drug enteropathy, irritable bowel syndrome and coeliac disease. For example, mesalazine is more useful in ulcerative colitis than in Crohn's disease.
Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any segment of the gastrointestinal tract from the mouth to the anus.

Ulcerative colitis

colitis ulcerosaColitisinflammatory colitis
Crohn's disease and ulcerative colitis are the principal types of inflammatory bowel disease. Conditions with similar symptoms as Crohn's disease includes intestinal tuberculosis, Behçet's disease, ulcerative colitis, nonsteroidal anti-inflammatory drug enteropathy, irritable bowel syndrome and coeliac disease. For example, mesalazine is more useful in ulcerative colitis than in Crohn's disease.
It is a kind of inflammatory bowel disease (IBD) along with Crohn's disease and microscopic colitis.

Diarrhea

diarrhoeadiarrheal diseaseschronic diarrhea
In spite of Crohn's and UC being very different diseases, both may present with any of the following symptoms: abdominal pain, diarrhea, rectal bleeding, severe internal cramps/muscle spasms in the region of the pelvis and weight loss.
These include lactose intolerance, irritable bowel syndrome, non-celiac gluten sensitivity, celiac disease, inflammatory bowel disease such as ulcerative colitis, hyperthyroidism, bile acid diarrhea, and a number of medications.

Primary sclerosing cholangitis

sclerosing cholangitisCholangitis, primary sclerosingcholangitis, sclerosing
Associated complaints or diseases include arthritis, pyoderma gangrenosum, primary sclerosing cholangitis, and non-thyroidal illness syndrome (NTIS).
This is further suggested by the observation that approximately 75% of individuals with PSC also have inflammatory bowel disease (IBD), most often ulcerative colitis.

Arthritis

arthriticjoint inflammationarthritic changes
Associated complaints or diseases include arthritis, pyoderma gangrenosum, primary sclerosing cholangitis, and non-thyroidal illness syndrome (NTIS).

Colonoscopy

colonoscopiescolonoscopecolonoscopes
Diagnosis is generally by assessment of inflammatory markers in stool followed by colonoscopy with biopsy of pathological lesions.
Colonoscopies are often used to diagnose colon cancer, but are also frequently used to diagnose inflammatory bowel disease.

Euthyroid sick syndrome

non-thyroidal illness syndromeLow-T3 syndromenonthyroidal illness syndrome
Associated complaints or diseases include arthritis, pyoderma gangrenosum, primary sclerosing cholangitis, and non-thyroidal illness syndrome (NTIS).
Outside the hospital setting euthyroid sick syndrome (non-thyroidal illness syndrome) has been assumed closely related with a series of chronic diseases, such as inflammatory bowel disease, chronic fatigue syndrome, and autoimmune disease.

Biopsy

biopsiestissue biopsybiopsied
Diagnosis is generally by assessment of inflammatory markers in stool followed by colonoscopy with biopsy of pathological lesions.
In inflammatory bowel disease (Crohn's disease and ulcerative colitis), frequent biopsies are taken to assess the activity of disease and to assess changes that precede malignancy.

Faecal calprotectin

Fecal calprotectinMeasurement of faecal calprotectin
Fecal calprotectin is useful as an initial investigation, which may suggest the possibility of IBD, as this test is sensitive but not specific for IBD.
Elevated faecal calprotectin indicates the migration of neutrophils to the intestinal mucosa, which occurs during intestinal inflammation, including inflammation caused by inflammatory bowel disease.

Irritable bowel syndrome

IBSSplenic flexure syndromeSplenic-flexure syndrome
Conditions with similar symptoms as Crohn's disease includes intestinal tuberculosis, Behçet's disease, ulcerative colitis, nonsteroidal anti-inflammatory drug enteropathy, irritable bowel syndrome and coeliac disease.
Worrisome features include onset at greater than 50 years of age, weight loss, blood in the stool, or a family history of inflammatory bowel disease.

Human gastrointestinal microbiota

gut floragut microbiotaintestinal flora
As a result of microbial symbiosis and immunity, alterations in the gut microbiome may contribute to inflammatory gut diseases.
Rhodotorula is most frequently found in individuals with inflammatory bowel disease while Candida is most frequently found in individuals with hepatitis B cirrhosis and chronic hepatitis B.

Behçet's disease

Behcet's diseaseBehcet syndromeBehcet's syndrome
Conditions with similar symptoms as Crohn's disease includes intestinal tuberculosis, Behçet's disease, ulcerative colitis, nonsteroidal anti-inflammatory drug enteropathy, irritable bowel syndrome and coeliac disease.
The oral lesions are similar to those found in inflammatory bowel disease and can be relapsing.

Inflammation

inflammatoryinflammatory responseinflamed
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.

Collagenous colitis

colitis, collagenous
Collagenous colitis is an inflammatory bowel disease affecting the colon specifically with peak incidence in the 5th decade of life, affecting women more than men.

Nonsteroidal anti-inflammatory drug

NSAIDNSAIDsnon-steroidal anti-inflammatory drug
Conditions with similar symptoms as Crohn's disease includes intestinal tuberculosis, Behçet's disease, ulcerative colitis, nonsteroidal anti-inflammatory drug enteropathy, irritable bowel syndrome and coeliac disease.
NSAIDs should be used with caution in individuals with inflammatory bowel disease (e.g., Crohn's disease or ulcerative colitis) due to their tendency to cause gastric bleeding and form ulceration in the gastric lining.

Autoimmune disease

autoimmune diseasesautoimmune disorderautoimmune
Inflammatory bowel diseases fall into the class of autoimmune diseases, in which the body's own immune system attacks elements of the digestive system.
Some common diseases that are generally considered autoimmune include celiac disease, diabetes mellitus type 1, Graves' disease, inflammatory bowel disease, multiple sclerosis, psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.

Mesalazine

mesalamine5-aminosalicylic acidAsacol
For example, mesalazine is more useful in ulcerative colitis than in Crohn's disease.
Mesalazine, also known as mesalamine or 5-aminosalicylic acid (5-ASA), is a medication used to treat inflammatory bowel disease, including ulcerative colitis and Crohn's disease.

Weight loss

weight-losslose weightlosing weight
In spite of Crohn's and UC being very different diseases, both may present with any of the following symptoms: abdominal pain, diarrhea, rectal bleeding, severe internal cramps/muscle spasms in the region of the pelvis and weight loss.

Small intestine

small bowelsmall intestinessmall
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.

Pouchitis

Between one-quarter and one-half of patients with ileo-anal pouches do have to manage occasional or chronic pouchitis.
Pouchitis is inflammation of the ileal pouch (an artificial rectum surgically created out of ileal gut tissue in patients who have undergone a colectomy), which is created in the management of patients with ulcerative colitis, indeterminate colitis, FAP, or, rarely, other colitides.

TNF inhibitor

anti-TNFinhibits TNF-alphaTNF alpha blocker
Generally, depending on the level of severity, IBD may require immunosuppression to control the symptoms, with drugs such as prednisone, TNF inhibitors, azathioprine (Imuran), methotrexate, or 6-mercaptopurine.
TNF is involved in autoimmune and immune-mediated disorders such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, psoriasis, hidradenitis suppurativa and refractory asthma, so TNF inhibitors may be used in their treatment.

Biological therapy for inflammatory bowel disease

biologic agentsbiologic therapy
Biological therapy for inflammatory bowel disease, especially the TNF inhibitors, are used in people with more severe or resistant Crohn's disease and sometimes in ulcerative colitis.
Inflammatory bowel disease (IBD), a collection of systemic diseases involving inflammation of the gastrointestinal tract, includes two (or three) diseases of unknown causation: ulcerative colitis, which affects only the large bowel; Crohn's disease, which can affect the entire gastrointestinal tract; and indeterminate colitis, which consists of large bowel inflammation that shows elements of both Crohn's disease and ulcerative colitis.

Budesonide

Entocort ECPulmicortRhinocort
Controlled release Budesonide is used for mild ileal Crohn's disease.
The pills in a delayed release form and rectal forms may be used for inflammatory bowel disease including Crohn's disease, ulcerative colitis and microscopic colitis.

Azathioprine

ImuranAzahexalAzasan
Generally, depending on the level of severity, IBD may require immunosuppression to control the symptoms, with drugs such as prednisone, TNF inhibitors, azathioprine (Imuran), methotrexate, or 6-mercaptopurine.
It is also an important therapy and steroid-sparing agent for inflammatory bowel disease (such as Crohn's disease and ulcerative colitis) and for multiple sclerosis.

Colitis

pseudomembranous colitisinfectious colitisbacterial colitis
Conditions with similar symptoms as ulcerative colitis includes acute self-limiting colitis, amebic colitis, schistosomiasis, Crohn's disease, colon cancer, irritable bowel syndrome, intestinal tuberculosis and nonsteroidal anti-inflammatory drug enteropathy.