Inflammatory bowel disease

inflammatory bowel diseasesIBDindeterminate colitisbowelsI'''nflammatory bowel diseaseinflamatory bowel diseasebowel disorderIBDsinflammation of the bowelInflammatory bowel disease (IBD)
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.wikipedia
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Crohn's disease

Crohn’s diseaseCrohnchron
Crohn's disease and ulcerative colitis are the principal types of inflammatory bowel disease. Conditions with similar symptoms as Crohn's disease includes intestinal tuberculosis, Behçet's disease, ulcerative colitis, nonsteroidal anti-inflammatory drug enteropathy, irritable bowel syndrome and coeliac disease. For example, mesalazine is more useful in ulcerative colitis than in Crohn's disease.
Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any part of the gastrointestinal tract from mouth to anus.

Ulcerative colitis

colitis ulcerosainflammatory colitiscolitis
Crohn's disease and ulcerative colitis are the principal types of inflammatory bowel disease. Conditions with similar symptoms as Crohn's disease includes intestinal tuberculosis, Behçet's disease, ulcerative colitis, nonsteroidal anti-inflammatory drug enteropathy, irritable bowel syndrome and coeliac disease. For example, mesalazine is more useful in ulcerative colitis than in Crohn's disease.
It is a kind of inflammatory bowel disease (IBD) along with Crohn's disease and microscopic colitis.

Diarrhea

diarrhoeadiarrheal diseaseschronic diarrhea
In spite of Crohn's and UC being very different diseases, both may present with any of the following symptoms: abdominal pain, diarrhea, rectal bleeding, severe internal cramps/muscle spasms in the region of the pelvis and weight loss.
These include lactose intolerance, irritable bowel syndrome, non-celiac gluten sensitivity, celiac disease, inflammatory bowel disease, hyperthyroidism, bile acid diarrhea, and a number of medications.

Primary sclerosing cholangitis

sclerosing cholangitischolangitis, sclerosingPSC
Associated complaints or diseases include arthritis, pyoderma gangrenosum, primary sclerosing cholangitis, and non-thyroidal illness syndrome (NTIS).
This is further suggested by the observation that approximately 75% of individuals with PSC also have inflammatory bowel disease (IBD), most often ulcerative colitis.

Arthritis

arthriticjoint inflammationjoint pain
Associated complaints or diseases include arthritis, pyoderma gangrenosum, primary sclerosing cholangitis, and non-thyroidal illness syndrome (NTIS).
Inflammatory bowel disease (including Crohn's disease and ulcerative colitis)

Irritable bowel syndrome

IBSirritable bowelbowel
Conditions with similar symptoms as Crohn's disease includes intestinal tuberculosis, Behçet's disease, ulcerative colitis, nonsteroidal anti-inflammatory drug enteropathy, irritable bowel syndrome and coeliac disease.
Worrisome features include onset at greater than 50 years of age, weight loss, blood in the stool, or a family history of inflammatory bowel disease.

Faecal calprotectin

Fecal calprotectinMeasurement of faecal calprotectin
Fecal calprotectin is useful as an initial investigation, which may suggest the possibility of IBD, as this test is sensitive but not specific for IBD.
Elevated faecal calprotectin indicates the migration of neutrophils to the intestinal mucosa, which occurs during intestinal inflammation, including inflammation caused by inflammatory bowel disease.

Colonoscopy

colonoscopiescolonoscopiccolonoscope
Diagnosis is generally by assessment of inflammatory markers in stool followed by colonoscopy with biopsy of pathological lesions.
Colonoscopies are often used to diagnose colon cancer, but are also frequently used to diagnose inflammatory bowel disease.

Collagenous colitis

colitis, collagenous
Microscopic colitis subdivided into collagenous colitis and lymphocytic colitis
Collagenous colitis is an inflammatory bowel disease affecting the colon specifically with peak incidence in the 5th decade of life, affecting women more than men.

Behçet's disease

behcet syndromeBehçetBehcet
Conditions with similar symptoms as Crohn's disease includes intestinal tuberculosis, Behçet's disease, ulcerative colitis, nonsteroidal anti-inflammatory drug enteropathy, irritable bowel syndrome and coeliac disease.
The oral lesions are similar to those found in inflammatory bowel disease and can be relapsing.

Euthyroid sick syndrome

non-thyroidal illness syndromenonthyroidal illness syndromeLow-T3 syndrome
Associated complaints or diseases include arthritis, pyoderma gangrenosum, primary sclerosing cholangitis, and non-thyroidal illness syndrome (NTIS).
Outside the hospital setting euthyroid sick syndrome (non-thyroidal illness syndrome) has been assumed closely related with a series of chronic diseases, such as inflammatory bowel disease, chronic fatigue syndrome, and autoimmune disease.

Nonsteroidal anti-inflammatory drug

non-steroidal anti-inflammatory drugNSAIDsnonsteroidal anti-inflammatory drugs
Conditions with similar symptoms as Crohn's disease includes intestinal tuberculosis, Behçet's disease, ulcerative colitis, nonsteroidal anti-inflammatory drug enteropathy, irritable bowel syndrome and coeliac disease.
People that suffer with inflammatory bowel disease (Crohn's disease or ulcerative colitis)

Gut flora

gut microbiotaintestinal floragut bacteria
As a result of microbial symbiosis and immunity, alterations in the gut microbiome may contribute to inflammatory gut diseases.
Rhodotorula is most frequently found in individuals with inflammatory bowel disease while Candida is most frequently found in individuals with hepatitis B cirrhosis and chronic hepatitis B.

Mesalazine

mesalamine5-aminosalicylic acidQuintasa
For example, mesalazine is more useful in ulcerative colitis than in Crohn's disease.
Mesalazine, also known as mesalamine or 5-aminosalicylic acid (5-ASA), is an aminosalicylate anti-inflammatory drug used to treat inflammatory bowel disease, including ulcerative colitis, or inflamed anus or rectum, and to maintain remission in Crohn's disease.

Autoimmune disease

autoimmune diseasesautoimmune disorderautoimmune
Inflammatory bowel diseases fall into the class of autoimmune diseases, in which the body's own immune system attacks elements of the digestive system.
Some common diseases that are generally considered autoimmune include celiac disease, diabetes mellitus type 1, Graves' disease, inflammatory bowel disease, multiple sclerosis, psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.

Biopsy

biopsiestissue biopsybiopsied
Diagnosis is generally by assessment of inflammatory markers in stool followed by colonoscopy with biopsy of pathological lesions.
In inflammatory bowel disease (Crohn's disease and ulcerative colitis), frequent biopsies are taken to assess the activity of disease and to assess changes that precede malignancy.

TNF inhibitor

anti-TNFinhibits TNF-alphaTNF blockers
Generally, depending on the level of severity, IBD may require immunosuppression to control the symptoms, with drugs such as prednisone, TNF inhibitors, azathioprine (Imuran), methotrexate, or 6-mercaptopurine.
TNF is involved in autoimmune and immune-mediated disorders such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, psoriasis, hidradenitis suppurativa and refractory asthma, so TNF inhibitors may be used in their treatment.

Pouchitis

A small percentage of patients with ileo-anal pouches do have to manage occasional or chronic pouchitis.
Pouchitis is inflammation of the ileal pouch (an artificial rectum surgically created out of ileal gut tissue in patients who have undergone a colectomy), which is created in the management of patients with ulcerative colitis, indeterminate colitis, FAP, or, rarely, other colitides.

Biological therapy for inflammatory bowel disease

Biological therapiesbiologic therapybiologic agents
Biological therapy for inflammatory bowel disease, especially the TNF inhibitors, are used in people with more severe or resistant Crohn's disease and sometimes in ulcerative colitis.
Inflammatory bowel disease (IBD), a collection of systemic diseases involving inflammation of the gastrointestinal tract, includes two (or three) diseases of unknown causation: ulcerative colitis, which affects only the large bowel; Crohn's disease, which can affect the entire gastrointestinal tract; and indeterminate colitis, which consists of large bowel inflammation that shows elements of both Crohn's disease and ulcerative colitis.

Colorectal cancer

colon cancerbowel cancerintestinal cancer
Conditions with similar symptoms as ulcerative colitis includes acute self-limiting colitis, amebic colitis, schistosomiasis, Crohn's disease, colon cancer, irritable bowel syndrome, intestinal tuberculosis and nonsteroidal anti-inflammatory drug enteropathy.
Another risk factor is inflammatory bowel disease, which includes Crohn's disease and ulcerative colitis.

Budesonide

Controlled release Budesonide is used for mild ileal Crohn's disease.
The pills in a delayed release form and rectal forms may be used for inflammatory bowel disease including Crohn's disease, ulcerative colitis and microscopic colitis.

Azathioprine

Generally, depending on the level of severity, IBD may require immunosuppression to control the symptoms, with drugs such as prednisone, TNF inhibitors, azathioprine (Imuran), methotrexate, or 6-mercaptopurine.
It is also an important therapy and steroid-sparing agent for inflammatory bowel disease (such as Crohn's disease and ulcerative colitis) and for multiple sclerosis.

FODMAP

Low-FODMAP dietlow-FODMAP dietsdiet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols
Dietary interventions, including certain exclusion diets, low fiber diets, and low-FODMAP diets have some benefits.
It can ameliorate and mask the digestive symptoms of serious diseases, such as celiac disease, inflammatory bowel disease and colon cancer, avoiding their correct diagnosis and therapy.

Inflammation

inflammatoryinflammatory responseinflamed
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.
Inflammatory bowel diseases

Toxic megacolon

megacolon, toxic
Fatalities due to complications such as toxic megacolon, bowel perforation and surgical complications are also rare..
Toxic megacolon is usually a complication of inflammatory bowel disease, such as ulcerative colitis and, more rarely, Crohn's disease, and of some infections of the colon, including Clostridium difficile infections, which have led to pseudomembranous colitis.