Agent that alters the force or energy of muscular contractions.- Inotrope
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Hormone and medication which is involved in regulating visceral functions .
A case has been made for the use of adrenaline infusion in place of the widely accepted treatment of inotropes for preterm infants with clinical cardiovascular compromise.
Phosphodiesterase inhibiting drug used in therapy for respiratory diseases such as chronic obstructive pulmonary disease and asthma under a variety of brand names.
increasing heart muscle contractility and efficiency (positive inotrope)
Medical emergency resulting from inadequate blood flow due to the dysfunction of the ventricles of the heart.
Medications that improve the heart's ability to contract (positive inotropes) may help; however, it is unclear which is best and at present there is no convincing evidence supporting inotropic or vasodilating therapy to reduce mortality in hemodynamically unstable patients.
Peptide hormone that causes vasoconstriction and an increase in blood pressure.
Angiotensin II results in increased inotropy, chronotropy, catecholamine (norepinephrine) release, catecholamine sensitivity, aldosterone levels, vasopressin levels, and cardiac remodeling and vasoconstriction through AT1 receptors on peripheral vessels (conversely, AT2 receptors impair cardiac remodeling).
Myocardial contractility represents the innate ability of the heart muscle (cardiac muscle or myocardium) to contract.
Contractility may be iatrogenically altered by the administration of inotropic agents.
Selective β1 receptor blocker medication.
By working on the beta-1 receptor of the cardiac muscle cells, it yields both a chronotropic and inotropic effect.
Functional deterioration of a structure or system that had been previously working with the help of allostatic compensation.
Short-term treatment of cardiac decompensation can be achieved through administration of dobutamine, resulting in an increase in heart contractility via an inotropic effect.
Calcium channel blockers (CCB), calcium channel antagonists or calcium antagonists are a group of medications that disrupt the movement of calcium through calcium channels.
Reducing the force of contraction of the myocardium is known as the negative inotropic effect of calcium channel blockers.
Medication used in the treatment of cardiogenic shock and severe heart failure.
Dobutamine is used to treat acute but potentially reversible heart failure, such as which occurs during cardiac surgery or in cases of septic or cardiogenic shock, on the basis of its positive inotropic action.
Set of manifestations caused by the failure of the heart's function as a pump supporting the blood flow through the body; its signs and symptoms result from a structural and/or functional abnormality of the heart, that disrupts its filling with blood or its ejecting of it during each heart beat.
Certain calcium channel blockers, such as diltiazem and verapamil, are known to decrease the force with which the heart ejects blood, thus are not recommended in people with heart failure with a reduced ejection fraction.