itchingpruritusitchinesspruriticitchypruritisitchy skinpruriginousAnogenital pruritusgeneralized itching
Itch (also known as pruritus) is a sensation that causes the desire or reflex to scratch.wikipedia
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Atopic dermatitis

atopic eczemaatopiceczema
This can be problematic with chronic itch patients, such as ones with atopic dermatitis, who may scratch affected spots until they no longer produce a pleasant or painful sensation, instead of when the itch sensation disappears.
It results in itchy, red, swollen, and cracked skin.

Scratch reflex

Pain creates a withdrawal reflex, whereas itch leads to a scratch reflex.
Alternatively, some sensory neurons can respond to a chemical stimulus that produces an itch sensation.


scabicideCrusted scabiesNorwegian scabies
The most common symptoms are severe itchiness and a pimple-like rash.


plaque psoriasispsoriasis vulgarispsoriatic
This is comparable to the 2–3% of the population suffering from psoriasis.
These skin patches are typically red, dry, itchy, and scaly.


allergiesallergic reactionallergic
Symptoms of food allergy include abdominal pain, bloating, vomiting, diarrhea, itchy skin, and swelling of the skin during hives.


eczemaallergic dermatitischronic eczema
These diseases are characterized by itchiness, red skin and a rash.


Around the third day after penetration, erythema and skin tenderness are felt, accompanied by pruritus (severe itching) and a black furuncular nodule surrounded by a white halo of stretched skin caused by the expansion of the flea.

Balsam of Peru

Myroxylon balsamumBalsambalsam oil
It may cause inflammation, redness, swelling, soreness, itching, and blisters, including allergic contact dermatitis, stomatitis (inflammation and soreness of the mouth or tongue), cheilitis (inflammation, rash, or painful erosion of the lips, oropharyngeal mucosa, or angles of their mouth), pruritus, hand eczema, generalized or resistant plantar dermatitis, rhinitis, and conjunctivitis.

Insect bites and stings

insect biteinsect bitesInsect sting
Bites from mosquitoes and fleas are more likely to cause itching than pain.


Obstructive jaundiceicteruscholestatic jaundice
It is commonly associated with itchiness.


sun burnburnSunburns
Other symptoms can include blistering, swelling (edema), pruritus (itching), peeling skin, rash, nausea, fever, chills, and fainting (syncope).


lymphomaslymphatic cancerlymphosarcoma
Signs and symptoms may include enlarged lymph nodes, fever, drenching sweats, unintended weight loss, itching, and constantly feeling tired.


cholestaticcholestatic jaundicecholestatic hepatotoxicity


opioidsopioid-induced constipationopioid analgesic
Neurogenic itch, which is itch induced centrally but with no neural damage, is mostly associated with increased accumulation of exogenous opioids and possibly synthetic opioids.
Side effects of opioids may include itchiness, sedation, nausea, respiratory depression, constipation, and euphoria.


diabetes mellitusdiabeticdiabetics
In addition to the known ones above, they include blurred vision, headache, fatigue, slow healing of cuts, and itchy skin.

Crab louse

pubic licecrabsPthirus pubis
The main symptom of infestation with crab lice is itching, usually in the pubic-hair area, resulting from hypersensitivity to louse saliva, which can become stronger over two or more weeks following initial infestation.


dry skinxerosisdry
Symptoms most associated with xeroderma are scaling (the visible peeling of the outer skin layer), itching, and skin cracking.

Athlete's foot

tinea pedisathlete’s footathletes foot
Because athlete's foot may itch, it may also elicit the scratch reflex, causing the host to scratch the infected area before they realize it.

Intrahepatic cholestasis of pregnancy

cholestasis of pregnancycholestatic jaundice of pregnancyHistory of jaundice or persistent pruritus during pregnancy
It typically presents with itching and can lead to complications for both mother and baby.

Uremic pruritus

Uremic pruritus is caused by chronic kidney failure and is the most common internal systemic cause of itching.


The primary afferent neurons responsible for histamine-induced itch are unmyelinated C-fibres.
Histamine is involved in the inflammatory response and has a central role as a mediator of itching.

Sensory nervous system

sensory systemsensorysensory organ
Itch has many similarities to pain, and while both are unpleasant sensory experiences, their behavioral response patterns are different.


* Menopause, or changes in hormonal balances associated with aging
heart palpitations, headache, dizziness, dry, itchy skin, thinning, tingling skin, weight gain, urinary incontinence,