Juvenile dermatomyositis

Childhood dermatomyositis
Juvenile dermatomyositis (JDM) is an idiopathic inflammatory myopathy (IMM) of presumed autoimmune dysfunction resulting in muscle weakness among other complications.wikipedia
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Dermatomyositis

Gottron's papulesAnti-Jo1dermatomyisitis
It manifests itself in children; it is the pediatric counterpart of dermatomyositis.
There is a form of this disorder that strikes children, known as juvenile dermatomyositis (JDM).

Myositis

muscle inflammationmyosistismyositides
Juvenile dermatomyositis (JDM) is an idiopathic inflammatory myopathy (IMM) of presumed autoimmune dysfunction resulting in muscle weakness among other complications.

Methotrexate

amethopterin(M)'''ethotrexateAbitrexate
Often, steroid-sparing drugs, such as methotrexate (a chemotherapy drug) or other DMARDs, are given to compensate for the reduction in oral steroids.
It is used as a disease-modifying treatment for some autoimmune diseases, including rheumatoid arthritis, juvenile dermatomyositis, psoriasis, psoriatic arthritis, lupus, sarcoidosis, Crohn's disease, eczema and many forms of vasculitis.

Immune system

immuneimmune responseimmune function
In JDM, the body's immune system attacks blood vessels throughout the body, causing inflammation called vasculitis.

Inflammation

inflammatoryinflammatory responseinflamed
In JDM, the body's immune system attacks blood vessels throughout the body, causing inflammation called vasculitis.

Vasculitis

vasculitidesvasculiticvasculitis, central nervous system
In JDM, the body's immune system attacks blood vessels throughout the body, causing inflammation called vasculitis.

United States

AmericanU.S.USA
In the United States, the incidence rate of JDMS is approximately 2-3 cases per million children per year.

Polymyositis

Other Idiopathic inflammatory myopathies include; juvenile polymyositis (PM), which is rare and not as common in children as in adults.

Rash

skin rashrashesskin rashes
One is a distinctive rash.

Face

human facefacialfacial feature
The rash often affects the face, eyelids, and hands, and sometimes the skin above joints, including the knuckles, knees, elbows, etc. The color of the rash is a pinkish purple, and is called heliotrope (after a flower of the same name with approximately this color).

Eyelid

eyelidspalpebralpalpebra
The rash often affects the face, eyelids, and hands, and sometimes the skin above joints, including the knuckles, knees, elbows, etc. The color of the rash is a pinkish purple, and is called heliotrope (after a flower of the same name with approximately this color).

Hand

handspalmpalms
The rash often affects the face, eyelids, and hands, and sometimes the skin above joints, including the knuckles, knees, elbows, etc. The color of the rash is a pinkish purple, and is called heliotrope (after a flower of the same name with approximately this color).

Knuckle

knuckles
The rash often affects the face, eyelids, and hands, and sometimes the skin above joints, including the knuckles, knees, elbows, etc. The color of the rash is a pinkish purple, and is called heliotrope (after a flower of the same name with approximately this color).

Knee

knee injuryknee jointknees
The rash often affects the face, eyelids, and hands, and sometimes the skin above joints, including the knuckles, knees, elbows, etc. The color of the rash is a pinkish purple, and is called heliotrope (after a flower of the same name with approximately this color).

Elbow

elbow jointelbow-jointelbows
The rash often affects the face, eyelids, and hands, and sometimes the skin above joints, including the knuckles, knees, elbows, etc. The color of the rash is a pinkish purple, and is called heliotrope (after a flower of the same name with approximately this color).

Heliotropium

heliotropeheliotropesheliotrope flower
The rash often affects the face, eyelids, and hands, and sometimes the skin above joints, including the knuckles, knees, elbows, etc. The color of the rash is a pinkish purple, and is called heliotrope (after a flower of the same name with approximately this color).

Allergy

allergiesallergic reactionallergic
On the hands and face, the rash very closely resembles allergies, eczema, fifth disease, or other more common skin condition, but the heliotrope color is unique to the inflammatory process of JDMS.

Dermatitis

eczemaallergic dermatitischronic eczema
On the hands and face, the rash very closely resembles allergies, eczema, fifth disease, or other more common skin condition, but the heliotrope color is unique to the inflammatory process of JDMS.

Fifth disease

Erythema infectiosumfifth feverSlap cheek
On the hands and face, the rash very closely resembles allergies, eczema, fifth disease, or other more common skin condition, but the heliotrope color is unique to the inflammatory process of JDMS.

Calcinosis

c'''alcinosisCalcinosis universaliscalcium deposit
Some children develop calcinosis, which are calcium deposits under the skin.

Muscle weakness

weaknessmyastheniafatigue
Muscle Inflammation causes muscle weakness, which can cause fatigue, clumsiness, not keeping up physically with peers, and eventually inability to perform tasks like climbing stairs, lifting objects, and performing other manual tasks.

Fatigue

exhaustionOverexertiontiredness
Muscle Inflammation causes muscle weakness, which can cause fatigue, clumsiness, not keeping up physically with peers, and eventually inability to perform tasks like climbing stairs, lifting objects, and performing other manual tasks.

Accident-proneness

clumsyklutzclumsiness
Muscle Inflammation causes muscle weakness, which can cause fatigue, clumsiness, not keeping up physically with peers, and eventually inability to perform tasks like climbing stairs, lifting objects, and performing other manual tasks.

Hoarse voice

dysphoniahoarsenessvoice changes
Other signs may include falling, dysphonia, or dysphagia.

Dysphagia

difficulty swallowingdifficulty in swallowingtrouble swallowing
Other signs may include falling, dysphonia, or dysphagia.