Kidney cancer

renal cancerkidneyrenalcancercancer of the kidneyrenal cell cancercancer of the left kidneykidney canceKidney Cancer,Kidney cancer:
Kidney cancer, also known as renal cancer, is a group of cancers that starts in the kidney.wikipedia
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Kidney

kidneysrenalkidney disorder
Kidney cancer, also known as renal cancer, is a group of cancers that starts in the kidney.
Urology addresses diseases of kidney (and urinary tract) anatomy: these include cancer, renal cysts, kidney stones and ureteral stones, and urinary tract obstruction.

Cancer

cancersmalignanciescancerous
Kidney cancer, also known as renal cancer, is a group of cancers that starts in the kidney.
Some types of cancer such as Hodgkin disease, leukemias and cancers of the liver or kidney can cause a persistent fever.

Bladder cancer

bladderbladder carcinomacancer of the bladder
Risk factors for RCC and TCC include smoking, certain pain medications, previous bladder cancer, being overweight, high blood pressure, certain chemicals, and a family history.
Blood in the urine may also be caused by other conditions, such as bladder or ureteric stones, infection, kidney disease, kidney cancers or vascular malformations, though these conditions (except kidney cancers) would typically be painful.

Transitional cell carcinoma

urothelial carcinomaurothelial cancertransitional cell cancer
The main types of kidney cancer are renal cell cancer (RCC), transitional cell cancer (TCC), and Wilms tumor. Another type of kidney cancer although less common, is transitional cell cancer (TCC) or urothelial carcinoma of the renal pelvis.
It is the second most common type of kidney cancer, but accounts for only five to 10 percent of all primary renal malignant tumors.

Hematuria

blood in the urinehaematuriabloody urine
Symptoms may include blood in the urine, lump in the abdomen, or back pain.

Clear-cell sarcoma of the kidney

clear cell sarcoma of the kidneyclear cellclear-cell sarcoma
Clear cell sarcoma of the kidney (CCSK) is an extremely rare type of kidney cancer comprising 3% of all pediatric renal tumours.

Renal cell carcinoma

renal cell cancerrenal carcinomakidney cancer
The main types of kidney cancer are renal cell cancer (RCC), transitional cell cancer (TCC), and Wilms tumor. The most common type of kidney malignancy is renal cell carcinoma, which is thought to originate from cells in the proximal convoluted tubule of the nephron.
Renal cell carcinoma (RCC) is a kidney cancer that originates in the lining of the proximal convoluted tubule, a part of the very small tubes in the kidney that transport primary urine.

Renal pelvis

pyelo-kidney pelvispelvic
Another type of kidney cancer although less common, is transitional cell cancer (TCC) or urothelial carcinoma of the renal pelvis.
The renal pelvis is the location of several kinds of kidney cancer and is affected by infection in pyelonephritis.

Collecting duct carcinoma

Bellini duct carcinomaCarcinoma of the Collecting Ducts of Bellini
Collecting duct carcinoma (CDC) is a type of kidney cancer that originates in the papillary duct of the kidney.

Nephrectomy

partial nephrectomynephroureterectomybilateral nephrectomy
In some cases this involves removing the whole kidney however most tumors are amenable to partial removal to eradicate the tumor and preserve the remaining normal portion of the kidney.
A Nephrectomy is the surgical removal of a kidney, performed to treat a number of kidney diseases including kidney cancer.

Proximal tubule

proximal convoluted tubuleproximal renal tubuleproximal tubular
The most common type of kidney malignancy is renal cell carcinoma, which is thought to originate from cells in the proximal convoluted tubule of the nephron.
Most renal cell carcinoma, the most common form of kidney cancer, arises from the convoluted tubules.

Cabozantinib

CometriqXL184
Cabozantinib also demonstrated an overall survival benefit over everolimus and was approved by the FDA as a second-line treatment in 2016.
In April 2016 the US FDA granted approval for marketing the tablet formulation as a second line treatment for kidney cancer and the same was approved in Europe in October of that year.

Temsirolimus

CCI-779torisel
Other treatment options include biological therapies such as everolimus, torisel, nexavar, sutent, and axitinib, the use of immunotherapy including interferon and interleukin-2.
mTOR is particularly important in the biology of renal cancer (RCC) owing to its function in regulating HIF-1a levels.

Sunitinib

Sutentsunitinib malateSU011248
Other treatment options include biological therapies such as everolimus, torisel, nexavar, sutent, and axitinib, the use of immunotherapy including interferon and interleukin-2.
In the UK, NICE refused (late 2008) to recommend sunitinib for late-stage renal cancer (kidney cancer) due to the high cost per QALY, estimated by NICE at £72,000/QALY and by Pfizer at £29,000/QALY.

Abdomen

abdominalabdominal musclesbelly
Symptoms may include blood in the urine, lump in the abdomen, or back pain.

Back pain

back spasmbackacheback spasms
Symptoms may include blood in the urine, lump in the abdomen, or back pain.

Metastasis

metastaticmetastasesmetastasized
Complications can include spread to the lungs or brain. For cancers that are confined to the kidney, the five-year survival rate is 93%, if it has spread to the surrounding lymph nodes it is 70%, and if it has spread widely, it is 12%.

Hypertension

high blood pressurehypertensivearterial hypertension
Risk factors for RCC and TCC include smoking, certain pain medications, previous bladder cancer, being overweight, high blood pressure, certain chemicals, and a family history.

WAGR syndrome

Wilms tumor, aniridia, genitourinary anomalies, and mental retardation syndromeWilms tumor-aniridia syndrome
Risk factors for Wilms tumor include a family history and certain genetic disorders such as WAGR syndrome.

Biopsy

Chemotherapy

chemotherapeuticantineoplasticantineoplastic agent
Treatment may include surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy.

Immunotherapy

immunomodulatorimmunomodulatoryimmunotherapies
Treatment may include surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy.

Targeted therapy

targeted therapiestargeted cancer therapyMolecular Targeted Therapy
Treatment may include surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy.

Lymph node

lymph glandslymph nodesfollicles
For cancers that are confined to the kidney, the five-year survival rate is 93%, if it has spread to the surrounding lymph nodes it is 70%, and if it has spread widely, it is 12%.