A report on Korsakoff syndrome
Disorder of the central nervous system characterized by amnesia, deficits in explicit memory, and confabulation.
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Wernicke–Korsakoff syndrome
6 linksWernicke–Korsakoff syndrome (WKS) is the combined presence of Wernicke encephalopathy (WE) and Korsakoff syndrome.
Amnesia
3 linksDeficit in memory caused by brain damage or disease, but it can also be caused temporarily by the use of various sedatives and hypnotic drugs.
Deficit in memory caused by brain damage or disease, but it can also be caused temporarily by the use of various sedatives and hypnotic drugs.
This type of dissociation between declarative and procedural memory can also be found in patients with diencephalic amnesia such as Korsakoff's syndrome.
Thiamine deficiency
2 linksMedical condition of low levels of thiamine .
Medical condition of low levels of thiamine .
Wernicke encephalopathy and Korsakoff syndrome are forms of dry beriberi.
Wernicke encephalopathy
2 linksPresence of neurological symptoms caused by biochemical lesions of the central nervous system after exhaustion of B-vitamin reserves, in particular thiamine (vitamin B1).
Presence of neurological symptoms caused by biochemical lesions of the central nervous system after exhaustion of B-vitamin reserves, in particular thiamine (vitamin B1).
The condition is part of a larger group of thiamine deficiency disorders that includes beriberi, in all its forms, and alcoholic Korsakoff syndrome.
Sergei Korsakoff
1 linksRussian neuropsychiatrist, known for his studies on alcoholic psychosis.
Russian neuropsychiatrist, known for his studies on alcoholic psychosis.
His name is lent to the eponymous Korsakoff's syndrome and Wernicke–Korsakoff syndrome.
Alcohol (drug)
1 linksPsychoactive drug that is the active ingredient in drinks such as beer, wine, and distilled spirits .
Psychoactive drug that is the active ingredient in drinks such as beer, wine, and distilled spirits .
Alcohol can cause brain damage, Wernicke's encephalopathy and Alcoholic Korsakoff syndrome (AKS) which frequently occur simultaneously, known as Wernicke–Korsakoff syndrome (WKS).
Confabulation
1 linksMemory error defined as the production of fabricated, distorted, or misinterpreted memories about oneself or the world.
Memory error defined as the production of fabricated, distorted, or misinterpreted memories about oneself or the world.
This type of confabulation is commonly seen in Korsakoff's syndrome.
Retrograde amnesia
2 linksLoss of memory-access to events that occurred or information that was learned in the past.
Loss of memory-access to events that occurred or information that was learned in the past.
RA can also progress and further deteriorate memory recollection, as in the case of Korsakoff syndrome and Alzheimer's disease, due to the ongoing nature of the damage caused by the illnesses.
Anterograde amnesia
2 linksLoss of the ability to create new memories after the event that caused amnesia, leading to a partial or complete inability to recall the recent past, while long-term memories from before the event remain intact.
Loss of the ability to create new memories after the event that caused amnesia, leading to a partial or complete inability to recall the recent past, while long-term memories from before the event remain intact.
Chronic alcoholism often leads to a thiamine (vitamin B1) deficiency in the brain, causing Korsakoff's syndrome, a neurological disorder which is generally preceded by an acute neurological condition known as Wernicke's encephalopathy (WE).
Gliosis
0 linksNonspecific reactive change of glial cells in response to damage to the central nervous system .
Nonspecific reactive change of glial cells in response to damage to the central nervous system .
Additionally, gliosis is present in a wide variety of CNS pathologies, including Alzheimer's disease, Korsakoff's syndrome, multiple system atrophy, prion disease, multiple sclerosis, AIDS dementia complex, vasculitis, Parkinson's disease, amyotrophic lateral sclerosis, and Huntington's disease.