A chest X-ray showing a tumor in the lung (marked by arrow)
A woman smoking a cigarette, the most common method of tobacco smoking
Relationship between cigarette consumption per person (blue) and male lung cancer rates (dark yellow) in the US over the century
Aztec women are handed flowers and smoking tubes before eating at a banquet, Florentine Codex, 16th century.
Risk of death from lung cancer is strongly correlated with smoking.
Gentlemen Smoking and Playing Backgammon in an Interior by Dirck Hals, 1627
CT scan showing a cancerous tumor in the left lung
Bonsack's cigarette rolling machine, as shown on U.S. patent 238,640
Primary pulmonary sarcoma in an asymptomatic 72-year-old male
A lengthy study conducted in order to establish the strong association necessary for legislative action (US cigarette consumption per person blue, male lung cancer rate brown)
Pie chart showing incidences of NSCLCs as compared to SCLCs shown at right, with fractions of smokers versus nonsmokers shown for each type
Tendu Patta (Leaf) collection for Beedi industries
Cross section of a human lung: The white area in the upper lobe is cancer; the black areas are discoloration due to smoking.
A graph that shows the efficiency of smoking as a way to absorb nicotine compared to other forms of intake.
Pneumonectomy specimen containing a squamous-cell carcinoma, seen as a white area near the bronchi
Sigmund Freud, whose doctor assisted his suicide because of oral cancer caused by smoking
Brachytherapy (internal radiotherapy) for lung cancer given via the airway
Common adverse effects of tobacco smoking. The more common effects are in bold face.
Monoclonal antibodies used in the treatment of NSCLC and their mechanism of action https://doi.org/10.3390/ph13110373
Skull with a burning cigarette, by Vincent van Gogh.
The main treatment arms of phase 3 clinical trials providing immunotherapy in the first line for patients with NSCLC https://doi.org/10.3390/ph13110373
An enclosed smoking area in a Japanese train station. Notice the air vent on the roof.
Overall survival in NSCLC patients treated with protocols incorporating immunotherapy in the first line for advanced or metastatic disease. Nasser NJ, Gorenberg M, Agbarya A. Pharmaceuticals 2020, 13(11), 373;
Lung cancer, incidence, mortality, and survival, England 1971–2011
Stage IA and IB lung cancer
Stage IIA lung cancer
Stage IIB lung cancer
One option for stage IIB lung cancer, with T2b; but if tumor is within 2 cm of the carina, this is stage 3
Stage IIIA lung cancer
Stage IIIA lung cancer, if there is one feature from the list on each side
Stage IIIA lung cancer
Stage IIIB lung cancer
Stage IIIB lung cancer
Stage IV lung cancer

The vast majority (85%) of cases of lung cancer are due to long-term tobacco smoking.

- Lung cancer

German scientists identified a link between smoking and lung cancer in the late 1920s, leading to the first anti-smoking campaign in modern history, albeit one truncated by the collapse of Nazi Germany at the end of World War II.

- Tobacco smoking
A chest X-ray showing a tumor in the lung (marked by arrow)

4 related topics

Alpha

Tobacco smoke in an Irish pub before a smoking ban came into effect on March 29, 2004

Tobacco smoke

Tobacco smoke in an Irish pub before a smoking ban came into effect on March 29, 2004

Tobacco smoke is a sooty aerosol produced by the incomplete combustion of tobacco during the smoking of cigarettes and other tobacco products.

Tobacco smoke, besides being an irritant and significant indoor air pollutant, is known to cause lung cancer, heart disease, chronic obstructive pulmonary disease (COPD), emphysema, and other serious diseases in smokers (and in non-smokers as well).

A coronal CT scan showing a malignant mesothelioma
Legend: → tumor ←, ✱ central pleural effusion, 1 & 3 lungs, 2 spine, 4 ribs, 5 aorta, 6 spleen, 7 & 8 kidneys, 9 liver

Cancer

Group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

Group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

A coronal CT scan showing a malignant mesothelioma
Legend: → tumor ←, ✱ central pleural effusion, 1 & 3 lungs, 2 spine, 4 ribs, 5 aorta, 6 spleen, 7 & 8 kidneys, 9 liver
Symptoms of cancer metastasis depend on the location of the tumor.
The GHS Hazard pictogram for carcinogenic substances
Share of cancer deaths attributed to tobacco in 2016.
The incidence of lung cancer is highly correlated with smoking.
Cancers are caused by a series of mutations. Each mutation alters the behavior of the cell somewhat.
The central role of DNA damage and epigenetic defects in DNA repair genes in carcinogenesis
Chest X-ray showing lung cancer in the left lung
Three measures of global cancer mortality from 1990 to 2017
Engraving with two views of a Dutch woman who had a tumor removed from her neck in 1689
University of Florida Cancer Hospital
CancerTreeMammal
An invasive ductal carcinoma of the breast (pale area at the center) surrounded by spikes of whitish scar tissue and yellow fatty tissue
An invasive colorectal carcinoma (top center) in a colectomy specimen
A squamous-cell carcinoma (the whitish tumor) near the bronchi in a lung specimen
A large invasive ductal carcinoma in a mastectomy specimen

Tobacco use is the cause of about 22% of cancer deaths.

The most common types of cancer in males are lung cancer, prostate cancer, colorectal cancer, and stomach cancer.

A 21mg dose nicotine patch applied to the left arm

Smoking cessation

A 21mg dose nicotine patch applied to the left arm
Some health organizations manage text messaging services to help people avoid smoking
Percent increase of success for six months over unaided attempts for each type of quitting (chart from West & Shiffman based on Cochrane review data
Individuals who sustained damage to the insula were able to more easily abstain from smoking.
Survival from age 35 of non-smokers, cigarette smokers and ex-smokers who stopped smoking between 25 and 34 years old. The ex-smokers line follows closely the non-smokers line.
Smokers as a percentage of the population for the United States, the Netherlands, Norway, Japan, and Finland

Smoking cessation, usually called quitting smoking or stopping smoking, is the process of discontinuing tobacco smoking.

Tobacco use leads most commonly to diseases affecting the heart and lungs, with smoking being a major risk factor for heart attacks, strokes, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), emphysema, and various types and subtypes of cancers (particularly lung cancer, cancers of the oropharynx, larynx, and mouth, esophageal and pancreatic cancer).

Survival from age 35 of non-smokers, cigarette smokers and ex-smokers who stopped smoking between 25 and 34 years old.

British Doctors Study

Survival from age 35 of non-smokers, cigarette smokers and ex-smokers who stopped smoking between 25 and 34 years old.
Survival from age 40 of non-smokers, cigarette smokers and ex-smokers who stopped smoking between 35 and 44 years old.
Survival from age 50 of non-smokers, cigarette smokers and ex-smokers who stopped smoking between 45 and 54 years old.
Survival from age 60 of non-smokers, cigarette smokers and ex-smokers who stopped smoking between 55 and 64 years old.

The British Doctors' Study was a prospective cohort study which ran from 1951 to 2001, and in 1956 provided convincing statistical proof that tobacco smoking increased the risk of lung cancer.