Management of HIV/AIDS

antiretroviralantiretroviral drugantiretroviral drugsHAARThighly active antiretroviral therapyantiretroviral therapyantiretroviral medicationanti-retroviralantiretroviralsantiretroviral treatment
The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs in an attempt to control HIV infection.wikipedia
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HIV/AIDS

AIDSHIVacquired immune deficiency syndrome
The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs in an attempt to control HIV infection.
Disease in a baby can often be prevented by giving both the mother and child antiretroviral medication.

Entry inhibitor

entry inhibitorsfusion inhibitorchemokine antagonists
Entry inhibitors (or fusion inhibitors) interfere with binding, fusion and entry of HIV-1 to the host cell by blocking one of several targets.
Entry inhibitors, also known as fusion inhibitors, are a class of antiretroviral drugs, used in combination therapy for the treatment of HIV infection.

Maraviroc

CelsentriSelzentry
Maraviroc and enfuvirtide are the two currently available agents in this class.
Maraviroc, brand-named Selzentry and Celsentri, is an antiretroviral drug in the CCR5 receptor antagonist class used in the treatment of HIV infection.

Enfuvirtide

Fuzeon
Maraviroc and enfuvirtide are the two currently available agents in this class.
Enfuvirtide (INN) is an HIV fusion inhibitor, the first of a class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.

Zidovudine

AZTazidothymidineRetrovir
Examples of currently used NRTIs include zidovudine, abacavir, lamivudine, emtricitabine, and tenofovir. In the era before multiple drug classes were available (pre-1997), the reverse-transcriptase inhibitors zidovudine, didanosine, zalcitabine, stavudine, and lamivudine were used serially or in combination leading to the development of multi-drug resistant mutations.
Zidovudine (ZDV), also known as azidothymidine (AZT), is an antiretroviral medication used to prevent and treat HIV/AIDS.

Lamivudine

3TCEpivir3TC (Lamivudine)
Examples of currently used NRTIs include zidovudine, abacavir, lamivudine, emtricitabine, and tenofovir. In the era before multiple drug classes were available (pre-1997), the reverse-transcriptase inhibitors zidovudine, didanosine, zalcitabine, stavudine, and lamivudine were used serially or in combination leading to the development of multi-drug resistant mutations.
Lamivudine, commonly called 3TC, is an antiretroviral medication used to prevent and treat HIV/AIDS.

Abacavir

Ziagen
Examples of currently used NRTIs include zidovudine, abacavir, lamivudine, emtricitabine, and tenofovir.
Similar to other nucleoside analog reverse-transcriptase inhibitors (NRTIs), abacavir is used together with other HIV medications, and is not recommended by itself.

Efavirenz

SustivaEtavirenz
1st generation NNRTIs include nevirapine and efavirenz.
Efavirenz (EFV), sold under the brand names Sustiva among others, is an antiretroviral medication used to treat and prevent HIV/AIDS.

Nevirapine

[18Viramune
1st generation NNRTIs include nevirapine and efavirenz.
It is generally recommended for use with other antiretroviral medication.

Integrase inhibitor

HIV integrase inhibitorsintegrase inhibitorsHIV integrase strand transfer inhibitor
Integrase inhibitors (also known as integrase nuclear strand transfer inhibitors or INSTIs) inhibit the viral enzyme integrase, which is responsible for integration of viral DNA into the DNA of the infected cell.
Integrase inhibitors (INIs) are a class of antiretroviral drug designed to block the action of integrase, a viral enzyme that inserts the viral genome into the DNA of the host cell.

Raltegravir

IsentressMK-0518
There are several integrase inhibitors currently under clinical trial, and raltegravir became the first to receive FDA approval in October 2007.
Raltegravir (RAL), sold under the brand name Isentress, is an antiretroviral medication used, together with other medication, to treat HIV/AIDS.

Dolutegravir

S/GSK1349572Tivicay
As of early 2014, two other clinically approved integrase inhibitors are elvitegravir and dolutegravir.
Dolutegravir (DTG), sold under the brand name Tivicay, is an antiretroviral medication used, together with other medication, to treat HIV/AIDS.

Nelfinavir

ViraceptNelfinavir mesylate
Examples of HIV protease inhibitors are lopinavir, indinavir, nelfinavir, amprenavir and ritonavir.
Nelfinavir (NFV; brand name Viracept) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV).

Ritonavir

NorvirNorvir (ritonavir)ritonovir
Examples of HIV protease inhibitors are lopinavir, indinavir, nelfinavir, amprenavir and ritonavir.
Ritonavir, sold under the trade name Norvir, is an antiretroviral medication used along with other medications to treat HIV/AIDS.

Darunavir

Prezista
Darunavir and atazanavir are currently recommended as first line therapy choices.
Darunavir (DRV), sold under the brand name Prezista among others, is an antiretroviral medication used to treat and prevent HIV/AIDS.

Atazanavir

Reyataz
Darunavir and atazanavir are currently recommended as first line therapy choices.
Atazanavir, sold under the trade name Reyataz among others, is an antiretroviral medication used to treat and prevent HIV/AIDS.

Indinavir

Crixivan
Examples of HIV protease inhibitors are lopinavir, indinavir, nelfinavir, amprenavir and ritonavir.
Indinavir (IDV; trade name Crixivan, made by Merck) is a protease inhibitor used as a component of highly active antiretroviral therapy to treat HIV/AIDS.

Stavudine

d4TZerit
In the era before multiple drug classes were available (pre-1997), the reverse-transcriptase inhibitors zidovudine, didanosine, zalcitabine, stavudine, and lamivudine were used serially or in combination leading to the development of multi-drug resistant mutations.
Stavudine (d4T), sold under the brand name Zerit among others, is an antiretroviral medication used to prevent and treat HIV/AIDS.

Fixed-dose combination (antiretroviral)

fixed dose combinationfixed-dose combinationantiretroviral FDCs
In recent years, drug companies have worked together to combine these complex regimens into simpler formulas, termed fixed-dose combinations.
Fixed-dose combinations of antiretrovirals are multiple antiretroviral drugs combined into a single pill, which helps reduce pill burden.

Didanosine

DDIddlVidex
In the era before multiple drug classes were available (pre-1997), the reverse-transcriptase inhibitors zidovudine, didanosine, zalcitabine, stavudine, and lamivudine were used serially or in combination leading to the development of multi-drug resistant mutations.
It is used in combination with other medications as part of highly active antiretroviral therapy (HAART).

Emtricitabine

Emtriva
Examples of currently used NRTIs include zidovudine, abacavir, lamivudine, emtricitabine, and tenofovir.
Emtricitabine is indicated in combination with other antiretroviral agents for the prevention and treatment of HIV infection in adults.

HIV

human immunodeficiency virusHIV-positiveHIV positive
There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle.
Viral recombination produces genetic variation that likely contributes to the evolution of resistance to anti-retroviral therapy.

Lamivudine/zidovudine

CombivirZidovudine and lamivudine
It is a combination of two antiretroviral medications, lamivudine and zidovudine.

Emtricitabine/tenofovir

Truvadatenofovir/emtricitabineTenefovir
It is a fixed-dose combination of two antiretroviral medications: tenofovir disoproxil and emtricitabine.