Methaqualone became increasingly popular as a recreational drug and club drug in the late 1960s and 1970s, known variously as "ludes" or "sopers" (also "soaps") in the U.S. and "mandrakes" and "mandies" in the UK, Australia and New Zealand.

Club drugs range from entactogens such as MDMA ("ecstasy"), 2C-B ("nexus") and inhalants (e.g., nitrous oxide and poppers) to stimulants (e.g., amphetamine and cocaine), depressants/sedatives (Quaaludes, GHB, Rohypnol) and psychedelic and hallucinogenic drugs (LSD, magic mushrooms and DMT).

Its use peaked in the early 1970s for the treatment of insomnia, and as a sedative and muscle relaxant.

Other skeletal muscle relaxants of that type used around the world come from a number of drug categories and other drugs used primarily for this indication include orphenadrine (anticholinergic), chlorzoxazone, tizanidine (clonidine relative), diazepam, tetrazepam and other benzodiazepines, mephenoxalone, methocarbamol, dantrolene, baclofen, Drugs once but no longer or very rarely used to relax skeletal muscles include meprobamate, barbiturates, methaqualone, glutethimide and the like; some subcategories of opioids have muscle relaxant properties, and some are marketed in combination drugs with skeletal and/or smooth muscle relaxants such as whole opium products, some ketobemidone, piritramide and fentanyl preparations and Equagesic.

Methaqualone, formerly sold under the brand name Quaalude and Mandrax, was a sedative and hypnotic medication.

Examples of quinazolinones include cloroqualone, diproqualone, etaqualone (Aolan, Athinazone, Ethinazone), mebroqualone, mecloqualone (Nubarene, Casfen), and methaqualone (Quaalude).

Methaqualone became increasingly popular as a recreational drug and club drug in the late 1960s and 1970s, known variously as "ludes" or "sopers" (also "soaps") in the U.S. and "mandrakes" and "mandies" in the UK, Australia and New Zealand.

methaqualone (Sopor, Mandrax; "Quaaludes")

It is a member of the quinazolinone class.

Methaqualone (Quaalude)

An overdose can cause delirium, convulsions, hypertonia, hyperreflexia, vomiting, kidney failure, coma, and death through cardiac or respiratory arrest.

Methaqualone

The DEA has also added the methaqualone analogue mecloqualone (also a result of some incomplete clandestine syntheses) to Schedule I

Mecloqualone (Nubarene, Casfen) is a Quinazolinone-class GABAergic and is an analogue of methaqualone that was first made in 1960 and marketed mainly in France and some other European countries.

Bill Cosby sexual assault allegations

In his testimony, Cosby admitted to casual sex involving recreational use of the sedative-hypnotic methaqualone (Quaaludes) with a series of young women, and he acknowledged that his dispensing the prescription drug was illegal.

In Canada, methaqualone is listed in Schedule III of the Controlled Drugs and Substances Act and requires a prescription but is Schedule I according to NAPRA.

Methaqualone (2-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone) and any salt thereof

In the United States it was withdrawn in 1982 and made a Schedule I drug in 1984.

Methaqualone (Quaalude, Sopor, Mandrax), a sedative that was previously used for similar purposes as barbiturates, until it was rescheduled.

Methaqualone was first synthesized in India in 1951 by Indra Kishore Kacker and Syed Husain Zaheer, for use as an antimalarial drug.

In 1951, along with Indra Kishore Kacker, he was the first to synthesize Methaqualone.

Its use peaked in the early 1970s for the treatment of insomnia, and as a sedative and muscle relaxant. Methaqualone, formerly sold under the brand name Quaalude and Mandrax, was a sedative and hypnotic medication. Methaqualone is a sedative that increases the activity of the GABA receptors in the brain and nervous system.

Its use peaked in the early 1970s for the treatment of insomnia, and as a sedative and muscle relaxant.

The substance was sold both as a free base and as salt (hydrochloride).

Methaqualone is a sedative that increases the activity of the GABA receptors in the brain and nervous system.

Methaqualone was not recommended for use while pregnant and is in pregnancy category D.

An overdose can cause delirium, convulsions, hypertonia, hyperreflexia, vomiting, kidney failure, coma, and death through cardiac or respiratory arrest.

An overdose can cause delirium, convulsions, hypertonia, hyperreflexia, vomiting, kidney failure, coma, and death through cardiac or respiratory arrest.

An overdose can cause delirium, convulsions, hypertonia, hyperreflexia, vomiting, kidney failure, coma, and death through cardiac or respiratory arrest.

An overdose can cause delirium, convulsions, hypertonia, hyperreflexia, vomiting, kidney failure, coma, and death through cardiac or respiratory arrest.

An overdose can cause delirium, convulsions, hypertonia, hyperreflexia, vomiting, kidney failure, coma, and death through cardiac or respiratory arrest.

An overdose can cause delirium, convulsions, hypertonia, hyperreflexia, vomiting, kidney failure, coma, and death through cardiac or respiratory arrest.

An overdose can cause delirium, convulsions, hypertonia, hyperreflexia, vomiting, kidney failure, coma, and death through cardiac or respiratory arrest.

An overdose can cause delirium, convulsions, hypertonia, hyperreflexia, vomiting, kidney failure, coma, and death through cardiac or respiratory arrest.

An overdose can cause delirium, convulsions, hypertonia, hyperreflexia, vomiting, kidney failure, coma, and death through cardiac or respiratory arrest.