Methaqualone

Methaqualone became increasingly popular as a recreational drug and club drug in the late 1960s and 1970s, known variously as "ludes" or "sopers" (also "soaps") in the United States and "mandrakes" and "mandies" in the United Kingdom, Australia and New Zealand.

Club drugs range from entactogens such as MDMA ("ecstasy"), 2C-B ("nexus") and inhalants (e.g., nitrous oxide and poppers) to stimulants (e.g., amphetamine and cocaine), depressants/sedatives (Quaaludes, GHB, Rohypnol) and psychedelic and hallucinogenic drugs (LSD, magic mushrooms and DMT).

It is also a common date rape drug.

Other drugs that have been used include hypnotics such as zopiclone, methaqualone and the widely available zolpidem (Ambien), sedatives such as neuroleptics (anti-psychotics), chloral hydrate and some histamine H1 antagonists, common recreational drugs such as ethanol, cocaine, and less common anticholinergics, barbiturates, opioids, PCP, scopolamine, nasal spray ingredient oxymetazoline, and certain solvents like GHB, GBL, and BD.

Its use peaked in the early 1970s for the treatment of insomnia, and as a sedative and muscle relaxant.

Other skeletal muscle relaxants of that type used around the world come from a number of drug categories and other drugs used primarily for this indication include orphenadrine (anticholinergic), chlorzoxazone, tizanidine (clonidine relative), diazepam, tetrazepam and other benzodiazepines, mephenoxalone, methocarbamol, dantrolene, baclofen, Drugs once but no longer or very rarely used to relax skeletal muscles include meprobamate, barbiturates, methaqualone, glutethimide and the like; some subcategories of opioids have muscle relaxant properties, and some are marketed in combination drugs with skeletal and/or smooth muscle relaxants such as whole opium products, some ketobemidone, piritramide and fentanyl preparations and Equagesic.

Methaqualone was a sedative and hypnotic medication, formerly sold under the brand name Quaalude and Mandrax until commercial production was halted.

Examples of quinazolinones include cloroqualone, diproqualone, etaqualone (Aolan, Athinazone, Ethinazone), mebroqualone, mecloqualone (Nubarene, Casfen), and methaqualone (Quaalude).

Methaqualone became increasingly popular as a recreational drug and club drug in the late 1960s and 1970s, known variously as "ludes" or "sopers" (also "soaps") in the United States and "mandrakes" and "mandies" in the United Kingdom, Australia and New Zealand.

It is a member of the quinazolinone class.

An overdose can lead to nervous system shutdown, coma and death.

The DEA has also added the methaqualone analogue mecloqualone (also a result of some incomplete clandestine syntheses) to Schedule I as ACSCN 2572, with zero manufacturing quota.

Mecloqualone (Nubarene, Casfen) is a Quinazolinone-class GABAergic and is an analogue of methaqualone that was first made in 1960 and marketed mainly in France and some other European countries.

In his testimony, Cosby admitted to casual sex involving recreational use of the sedative-hypnotic methaqualone (Quaaludes) with a series of young women, and he acknowledged that his dispensing the prescription drug was illegal.

In Canada, methaqualone is listed in Schedule III of the Controlled Drugs and Substances Act and requires a prescription, but it is no longer manufactured.

In the United States it was withdrawn in 1982 and made a Schedule I drug in 1984.

Methaqualone was first synthesized in India in 1951 by Indra Kishore Kacker and Syed Husain Zaheer, for use as an antimalarial medication.

In 1951, along with Indra Kishore Kacker, he was the first to synthesize Methaqualone.

Methaqualone was a sedative and hypnotic medication, formerly sold under the brand name Quaalude and Mandrax until commercial production was halted.

Its use peaked in the early 1970s for the treatment of insomnia, and as a sedative and muscle relaxant.

The substance was sold both as a free base and as salt (hydrochloride).

Methaqualone is a sedative that increases the activity of the GABA receptors in the brain and nervous system, similarly to benzodiazepines and barbiturates.

Methaqualone is a sedative that increases the activity of the GABA receptors in the brain and nervous system, similarly to benzodiazepines and barbiturates.

Methaqualone is a sedative that increases the activity of the GABA receptors in the brain and nervous system, similarly to benzodiazepines and barbiturates.

Methaqualone was not recommended for use while pregnant and is in pregnancy category D.

An overdose can lead to nervous system shutdown, coma and death.

An overdose can lead to nervous system shutdown, coma and death.

Additional effects are delirium, convulsions, hypertonia, hyperreflexia, vomiting, kidney failure, coma, and death through cardiac or respiratory arrest.

Additional effects are delirium, convulsions, hypertonia, hyperreflexia, vomiting, kidney failure, coma, and death through cardiac or respiratory arrest.

Additional effects are delirium, convulsions, hypertonia, hyperreflexia, vomiting, kidney failure, coma, and death through cardiac or respiratory arrest.

Additional effects are delirium, convulsions, hypertonia, hyperreflexia, vomiting, kidney failure, coma, and death through cardiac or respiratory arrest.