A report on Midazolam
Benzodiazepine medication used for anesthesia, procedural sedation, and severe agitation.
- Midazolam29 related topics with Alpha
Benzodiazepine
11 linksFusion of a benzene ring and a diazepine ring.
Fusion of a benzene ring and a diazepine ring.
In the community, intravenous administration is not practical and so rectal diazepam or buccal midazolam are used, with a preference for midazolam as its administration is easier and more socially acceptable.
Lorazepam
9 linksBenzodiazepine medication.
Benzodiazepine medication.
Lorazepam is sometimes used as an alternative to midazolam in palliative sedation.
Propofol
5 linksShort-acting medication that results in a decreased level of consciousness and a lack of memory for events.
Short-acting medication that results in a decreased level of consciousness and a lack of memory for events.
Its use in these settings results in a faster recovery compared to midazolam.
WHO Model List of Essential Medicines
2 linksThe WHO Model List of Essential Medicines (aka Essential Medicines List or EML ), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
The WHO Model List of Essential Medicines (aka Essential Medicines List or EML ), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
Midazolam
Status epilepticus
3 linksSingle seizure lasting more than 5 minutes or 2 or more seizures within a 5-minute period without the person returning to normal between them.
Single seizure lasting more than 5 minutes or 2 or more seizures within a 5-minute period without the person returning to normal between them.
Possible benzodiazepines include intravenous lorazepam as well as intramuscular injections of midazolam.
Anterograde amnesia
2 linksLoss of the ability to create new memories after the event that caused amnesia, leading to a partial or complete inability to recall the recent past, while long-term memories from before the event remain intact.
Loss of the ability to create new memories after the event that caused amnesia, leading to a partial or complete inability to recall the recent past, while long-term memories from before the event remain intact.
This disorder is usually acquired in one of four ways: One cause is benzodiazepine drugs such as midazolam, flunitrazepam, lorazepam, temazepam, nitrazepam, triazolam, clonazepam, alprazolam, diazepam, and nimetazepam; all of these are known to have powerful amnesic effects.
Anesthesia
1 linksState of controlled, temporary loss of sensation or awareness that is induced for medical purposes.
State of controlled, temporary loss of sensation or awareness that is induced for medical purposes.
Drugs like midazolam produce amnesia through different pathways by blocking the formation of long-term memories.
Procedural sedation and analgesia
1 linksTechnique in which a sedating/dissociative medication is given, usually along with an analgesic medication, in order to perform non-surgical procedures on a patient.
Technique in which a sedating/dissociative medication is given, usually along with an analgesic medication, in order to perform non-surgical procedures on a patient.
Midazolam is a benzodiazepine that acts by stimulating inhibitory GABA receptors.
General anaesthesia
1 linksMedically induced coma with loss of protective reflexes, resulting from the administration of either intravenous or inhalational general anaesthetic medications, often in combination with an analgesic and neuromuscular blocking agent.
Medically induced coma with loss of protective reflexes, resulting from the administration of either intravenous or inhalational general anaesthetic medications, often in combination with an analgesic and neuromuscular blocking agent.
Midazolam, a benzodiazepine characterized by a rapid onset and short duration, is effective in reducing preoperative anxiety, including separation anxiety in children.
Benzodiazepine withdrawal syndrome
3 linksCluster of signs and symptoms that emerge when a person who has been taking benzodiazepines, either medically or recreationally, and has developed a physical dependence, undergoes dosage reduction or discontinuation.
Cluster of signs and symptoms that emerge when a person who has been taking benzodiazepines, either medically or recreationally, and has developed a physical dependence, undergoes dosage reduction or discontinuation.
Benzodiazepines with a half-life of less than 24 hours include alprazolam, bromazepam, brotizolam, flunitrazepam, loprazolam, lorazepam, lormetazepam, midazolam, nitrazepam, oxazepam, and temazepam.