Midazolam
Benzodiazepine medication used for anesthesia, procedural sedation, trouble sleeping, and severe agitation.
- Midazolam153 related topics
Anterograde amnesia
Loss of the ability to create new memories after the event that caused amnesia, leading to a partial or complete inability to recall the recent past, while long-term memories from before the event remain intact.
This disorder is usually acquired in one of four ways: One cause is benzodiazepine drugs such as midazolam, flunitrazepam, lorazepam, temazepam, nitrazepam, triazolam, clonazepam, alprazolam, diazepam, and nimetazepam; all of these are known to have powerful amnesic effects.
WHO Model List of Essential Medicines
The WHO Model List of Essential Medicines (aka Essential Medicines List or EML ), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
Midazolam
Anesthesia
Not to be confused with Paresthesia and Anesthetic.
Drugs like midazolam produce amnesia through different pathways by blocking the formation of long-term memories.
Psychomotor agitation
Symptom in various disorders and health conditions.
Intramuscular midazolam, lorazepam, or another benzodiazepine can be used both to sedate agitated patients and to control semi-involuntary muscle movements in cases of suspected akathisia.
Procedural sedation and analgesia
Technique in which a sedating/dissociative medication is given, usually along with an analgesic medication, in order to perform non-surgical procedures on a patient.
Midazolam is a benzodiazepine that acts by stimulating inhibitory GABA receptors.
Propofol
Short-acting medication that results in a decreased level of consciousness and a lack of memory for events.
Its use in these settings results in a faster recovery compared to midazolam.
Status epilepticus
Single seizure lasting more than 5 minutes or 2 or more seizures within a 5-minute period without the person returning to normal between them.
Possible benzodiazepines include intravenous lorazepam as well as intramuscular injections of midazolam.
Lorazepam
Benzodiazepine medication.
Lorazepam is sometimes used as an alternative to midazolam in palliative sedation.
Benzodiazepine
Fusion of a benzene ring and a diazepine ring.
In the community, intravenous administration is not practical and so rectal diazepam or buccal midazolam are used, with a preference for midazolam as its administration is easier and more socially acceptable.
End-of-life care
End-of-life care (EoLC) refers to health care for a person nearing the end of their life or in the advanced stage of a terminal illness.
Delirium, terminal anguish, restlessness (e.g. thrashing, plucking, or twitching). Typically controlled using clonazepam or midazolam, antipsychotics such as haloperidol or levomepromazine may also be used instead of, or concomitantly with benzodiazepines. Symptoms may also sometimes be alleviated by rehydration, which may reduce the effects of some toxic drug metabolites.