Molecular genetics

molecular geneticmolecularmolecular geneticistDNA evidencegeneticgenetic and moleculargeneticsamplificationgenetic researchgenetically
Molecular genetics is a sub-field of genetics that applies an "investigative approach" to determine the structure and/or function of genes in an organism’s genome using genetic screens.wikipedia
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Biochemistry

biochemistbiochemicalbiological chemistry
The field of study is based on the merging of several sub-fields in biology: classical Mendelian inheritance, cellular biology, molecular biology, biochemistry, and biotechnology.
A sub-discipline of both biology and chemistry, biochemistry can be divided in three fields; molecular genetics, protein science and metabolism.

Cell biology

cytologycell biologistcellular biology
The field of study is based on the merging of several sub-fields in biology: classical Mendelian inheritance, cellular biology, molecular biology, biochemistry, and biotechnology.
Research in cell biology is interconnected to other fields such as genetics, molecular genetics, biochemistry, molecular biology, medical microbiology, immunology, and cytochemistry.

Molecular biology

molecular biologistmolecularmolecular microbiology
The field of study is based on the merging of several sub-fields in biology: classical Mendelian inheritance, cellular biology, molecular biology, biochemistry, and biotechnology.
In the early 2000s, the study of gene structure and function, molecular genetics, has been among the most prominent sub-fields of molecular biology.

Forward genetics

forward geneticforwardforward genetic methods
Forward genetics is a molecular genetics technique used to identify genes or genetic mutations that produce a certain phenotype.
Forward genetics is the molecular genetics approach of determining the genetic basis responsible for a phenotype.

Viral vector

viral vectorsvectorvectors
Gene therapy delivers a copy of the missing, mutated, or desired gene via a modified virus or vector to the patient's target cells so that a functional form of the protein can then be produced and incorporated into the body.
Viral vectors were originally developed as an alternative to transfection of naked DNA for molecular genetics experiments.

History of genetics

geneticsTimeline of the history of geneticsgenes
A focus on new model organisms such as viruses and bacteria, along with the discovery of the double helical structure of DNA in 1953, marked the transition to the era of molecular genetics.

Genetic screen

positional cloningscreensscreen
Molecular genetics is a sub-field of genetics that applies an "investigative approach" to determine the structure and/or function of genes in an organism’s genome using genetic screens.

Mendelian inheritance

Mendelian geneticsMendelianMendel's laws
The field of study is based on the merging of several sub-fields in biology: classical Mendelian inheritance, cellular biology, molecular biology, biochemistry, and biotechnology.

Biotechnology

biotechbiotechnologicalBio-Technology
The field of study is based on the merging of several sub-fields in biology: classical Mendelian inheritance, cellular biology, molecular biology, biochemistry, and biotechnology.

Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

Watson and CrickMolecular structure of Nucleic Acidsstructure of DNA
Watson and Crick (in conjunction with Franklin and Wilkins) figured out the structure of DNA, a cornerstone for molecular genetics.

Rosalind Franklin

FranklinContribution of King's College London to the discovery of the structure of DNADr Rosalind Franklin
Watson and Crick (in conjunction with Franklin and Wilkins) figured out the structure of DNA, a cornerstone for molecular genetics.

Maurice Wilkins

Maurice Hugh Frederick WilkinsM.H.F. WilkinsProfessor Maurice Wilkins
Watson and Crick (in conjunction with Franklin and Wilkins) figured out the structure of DNA, a cornerstone for molecular genetics.

DNA

deoxyribonucleic aciddouble-stranded DNAdsDNA
Watson and Crick (in conjunction with Franklin and Wilkins) figured out the structure of DNA, a cornerstone for molecular genetics.

Restriction enzyme

restriction enzymesrestriction endonucleaserestriction endonucleases
The isolation of a restriction endonuclease in ''E.

Genetic engineering

genetically engineeredgenetically modifiedgenetic modification
coli'' by Arber and Linn in 1969 opened the field of genetic engineering.

Electrophoresis

electrophoreticelectrophoretic mobilitymobility
Restriction enzymes were used to linearize DNA for separation by electrophoresis and Southern blotting allowed for the identification of specific DNA segments via hybridization probes.

Southern blot

Southern blottingSouthern hybridizationblotting, southern
Restriction enzymes were used to linearize DNA for separation by electrophoresis and Southern blotting allowed for the identification of specific DNA segments via hybridization probes.

Hybridization probe

probeprobesDNA probe
Restriction enzymes were used to linearize DNA for separation by electrophoresis and Southern blotting allowed for the identification of specific DNA segments via hybridization probes.

Recombinant DNA

recombinantrecombinant proteingene splicing
In 1971, Berg utilized restriction enzymes to create the first recombinant DNA molecule and first recombinant DNA plasmid.

Plasmid

plasmidsepisomeplasmid vector
In 1971, Berg utilized restriction enzymes to create the first recombinant DNA molecule and first recombinant DNA plasmid.

Transformation (genetics)

transformationtransformedgenetic transformation
coli'', now known as bacterial transformation, and paved the way for molecular cloning.

DNA sequencing

DNA sequencesequencesequencing
The development of DNA sequencing techniques in the late 1970s, first by Maxam and Gilbert, and then by Frederick Sanger, was pivotal to molecular genetic research and enabled scientists to begin conducting genetic screens to relate genotypic sequences to phenotypes. Polymerase chain reaction (PCR) using Taq polymerase, invented by Mullis in 1985, enabled scientists to create millions of copies of a specific DNA sequence that could be used for transformation or manipulated using agarose gel separation.

Frederick Sanger

Fred SangerSangerFrederic Sanger
The development of DNA sequencing techniques in the late 1970s, first by Maxam and Gilbert, and then by Frederick Sanger, was pivotal to molecular genetic research and enabled scientists to begin conducting genetic screens to relate genotypic sequences to phenotypes. Polymerase chain reaction (PCR) using Taq polymerase, invented by Mullis in 1985, enabled scientists to create millions of copies of a specific DNA sequence that could be used for transformation or manipulated using agarose gel separation.

Polymerase chain reaction

PCRPCR amplificationpolymerase chain reaction (PCR)
The development of DNA sequencing techniques in the late 1970s, first by Maxam and Gilbert, and then by Frederick Sanger, was pivotal to molecular genetic research and enabled scientists to begin conducting genetic screens to relate genotypic sequences to phenotypes. Polymerase chain reaction (PCR) using Taq polymerase, invented by Mullis in 1985, enabled scientists to create millions of copies of a specific DNA sequence that could be used for transformation or manipulated using agarose gel separation.

Agarose gel electrophoresis

agarose gelagaroseelectrophoresis
The development of DNA sequencing techniques in the late 1970s, first by Maxam and Gilbert, and then by Frederick Sanger, was pivotal to molecular genetic research and enabled scientists to begin conducting genetic screens to relate genotypic sequences to phenotypes. Polymerase chain reaction (PCR) using Taq polymerase, invented by Mullis in 1985, enabled scientists to create millions of copies of a specific DNA sequence that could be used for transformation or manipulated using agarose gel separation.