Opioids are substances that act on opioid receptors to produce morphine-like effects.
- OpioidAbout 70 percent of morphine is used to make other opioids such as hydromorphone, oxymorphone, and heroin.
- Morphine42 related topics with Alpha
Heroin
18 linksHeroin, also known as diacetylmorphine and diamorphine among other names, is an opioid used as a recreational drug for its euphoric effects.
Black tar heroin is a variable admixture of morphine derivatives—predominantly 6-MAM (6-monoacetylmorphine), which is the result of crude acetylation during clandestine production of street heroin.
Oxycodone
12 linksOxycodone, sold under the brand names Roxicodone and OxyContin (which is the extended release form) among others, is a semi-synthetic opioid medication used for treatment of moderate to severe pain.
When taken by mouth, it has roughly 1.5 times the effect of the equivalent amount of morphine.
Codeine
10 linksCodeine is an opiate and prodrug of morphine used to treat pain, coughing, and diarrhea.
Codeine is a nonsynthetic opioid.
Analgesic
9 linksAnalgesic, pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain .
Analgesic, pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain .
In combination with opioid pain medication, paracetamol is now used for more severe pain such as cancer pain and after surgery.
Morphine, the archetypal opioid, and other opioids (e.g., codeine, oxycodone, hydrocodone, dihydromorphine, pethidine) all exert a similar influence on the cerebral opioid receptor system.
Controlled Substances Act
13 linksStatute establishing federal U.S. drug policy under which the manufacture, importation, possession, use, and distribution of certain substances is regulated.
Statute establishing federal U.S. drug policy under which the manufacture, importation, possession, use, and distribution of certain substances is regulated.
Heroin, is the brand name for diacetylmorphine or morphine diacetate, which is an inactive prodrug that exerts its effects after being converted into the major active metabolite morphine, and the minor metabolite 6-MAM - which itself is also rapidly converted to morphine. Some European countries still use it as a potent pain reliever in terminal cancer patients, and as second option, after morphine sulfate; it is about twice as potent, by weight, as morphine and, indeed, becomes morphine upon injection into the bloodstream. The two acetyl groups attached to the morphine make a prodrug which delivers morphine to the opioid receptors twice as fast as morphine can.
Fentanyl and most other strong pure opioid agonists, e.g. levorphanol
Hydromorphone
7 linksHydromorphone, also known as dihydromorphinone, and sold under the brand name Dilaudid among others, is an opioid used to treat moderate to severe pain.
Hydromorphone 2 mg IV is equivalent to approximately 10 mg morphine IV.
Pain management
7 linksAspect of medicine and health care involving relief of pain in various dimensions, from acute and simple to chronic and challenging.
Aspect of medicine and health care involving relief of pain in various dimensions, from acute and simple to chronic and challenging.
The Center for Disease Control recommends that physical therapy and exercise can be prescribed as a positive alternative to opioids for decreasing one's pain in multiple injuries, illnesses, or diseases.
Morphine is the gold standard to which all narcotics are compared.
Pethidine
8 linksPethidine, also known as meperidine and sold under the brand name Demerol among others, is a synthetic opioid pain medication of the phenylpiperidine class.
Compared with morphine, pethidine was thought to be safer, carry a lower risk of addiction, and to be superior in treating the pain associated with biliary spasm or renal colic due to its putative anticholinergic effects.
Opium
5 linksDried latex obtained from the seed capsules of the opium poppy Papaver somniferum.
Dried latex obtained from the seed capsules of the opium poppy Papaver somniferum.
Approximately 12 percent of opium is made up of the analgesic alkaloid morphine, which is processed chemically to produce heroin and other synthetic opioids for medicinal use and for the illegal drug trade.
Fentanyl
7 linksFentanyl, also spelled fentanil, is a powerful opioid used as a pain medication and, together with other medications, for anesthesia.
It is around 100 times stronger than morphine and about 50 times stronger than heroin.