NLRX1

NLRX1 or NLR family member X1, short for nucleotide-binding oligomerization domain, leucine rich repeat containing X1 is a protein that in humans is encoded by the NLRX1 gene.wikipedia
19 Related Articles

NOD-like receptor

Nod-like receptorsNOD-like receptors (NLRs)(NOD)-like receptor
It is also known as NOD-like receptor X1, NLR family, X1, NOD5, NOD9, and CLR11.3, and is a member of the NOD-like receptor family of pattern recognition receptors.
A member of this subfamily is NLRX1.

NACHT domain

NACHTNACHT protein domain
NLRX1 has a unique protein structure composed of 3 protein domains: an N-terminal effector domain containing a mitochondrion localization signal; a central NACHT domain; a C-terminal leucine-rich repeat (LRR) domain.

Protein

proteinsproteinaceousstructural proteins
NLRX1 or NLR family member X1, short for nucleotide-binding oligomerization domain, leucine rich repeat containing X1 is a protein that in humans is encoded by the NLRX1 gene.

Gene

genesnumber of genesgene sequence
NLRX1 or NLR family member X1, short for nucleotide-binding oligomerization domain, leucine rich repeat containing X1 is a protein that in humans is encoded by the NLRX1 gene.

Pattern recognition receptor

pattern recognition receptorspattern recognition receptors (PRRs)(PRRs)
It is also known as NOD-like receptor X1, NLR family, X1, NOD5, NOD9, and CLR11.3, and is a member of the NOD-like receptor family of pattern recognition receptors.

Intracellular

intracellular spaceinside cellswithin the cell
NLRX1 is an intracellular protein that plays a role in the immune system.

Immune system

immuneimmune responseimmune function
NLRX1 is an intracellular protein that plays a role in the immune system.

Virus

virusesviralvirion
NLRX1 has been proposed to affect innate immunity to viruses by interfering with the mitochondrial antiviral signaling protein (MAVS)/retinoic-acid-inducible gene I (RIG-I) mitochondrial antiviral pathway., although this was recently questioned.

Mitochondrial antiviral-signaling protein

MAVSVISAIPS-1
NLRX1 has been proposed to affect innate immunity to viruses by interfering with the mitochondrial antiviral signaling protein (MAVS)/retinoic-acid-inducible gene I (RIG-I) mitochondrial antiviral pathway., although this was recently questioned.

RIG-I

DDX58retinoic acid-inducible gene Iretinoic acid-inducible gene-1 (RIG-1)
NLRX1 has been proposed to affect innate immunity to viruses by interfering with the mitochondrial antiviral signaling protein (MAVS)/retinoic-acid-inducible gene I (RIG-I) mitochondrial antiviral pathway., although this was recently questioned.

Mitochondrion

mitochondriamitochondrialmitochondrial membrane
NLRX1 has been proposed to affect innate immunity to viruses by interfering with the mitochondrial antiviral signaling protein (MAVS)/retinoic-acid-inducible gene I (RIG-I) mitochondrial antiviral pathway., although this was recently questioned.

Protein domain

domainsdomainstructural domain
NLRX1 has a unique protein structure composed of 3 protein domains: an N-terminal effector domain containing a mitochondrion localization signal; a central NACHT domain; a C-terminal leucine-rich repeat (LRR) domain.

N-terminus

N-terminalN terminusN-
NLRX1 has a unique protein structure composed of 3 protein domains: an N-terminal effector domain containing a mitochondrion localization signal; a central NACHT domain; a C-terminal leucine-rich repeat (LRR) domain.

Protein targeting

translocationtraffickingprotein sorting
NLRX1 has a unique protein structure composed of 3 protein domains: an N-terminal effector domain containing a mitochondrion localization signal; a central NACHT domain; a C-terminal leucine-rich repeat (LRR) domain.

C-terminus

C-terminalC-terminal domainC terminus
NLRX1 has a unique protein structure composed of 3 protein domains: an N-terminal effector domain containing a mitochondrion localization signal; a central NACHT domain; a C-terminal leucine-rich repeat (LRR) domain.

Leucine-rich repeat

leucine-rich repeatsLRRleucine rich repeat
NLRX1 has a unique protein structure composed of 3 protein domains: an N-terminal effector domain containing a mitochondrion localization signal; a central NACHT domain; a C-terminal leucine-rich repeat (LRR) domain.

CHI3L1

YKL-40Cartilage glycoprotein 39chitinase-like proteins
Cancer cells can offset RLH by stimulating NLRX1.