Nephrotoxicity

nephrotoxicnephrotoxinKidney damagekidney toxicitytoxic to the kidneyskidneyKidney injuryrenal toxicityespecially to the kidneysharm to kidneys
Nephrotoxicity is toxicity in the kidneys.wikipedia
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Gentamicin

gentamycinGaramycinAlcomicin
Gentamicin can cause inner ear problems and kidney problems.

Tacrolimus

FK506Prograftacrolimus binding protein 1a
Side effects can be severe and include infection, cardiac damage, hypertension, blurred vision, liver and kidney problems (tacrolimus nephrotoxicity), hyperkalemia, hypomagnesemia, hyperglycemia, diabetes mellitus, itching, lung damage (sirolimus also causes lung damage), and various neuropsychiatric problems such as loss of appetite, insomnia, posterior reversible encephalopathy syndrome, confusion, weakness, depression, vivid nightmares, cramps, neuropathy, seizures, tremors, and catatonia.

Toxicity

toxicnon-toxicnontoxic
Nephrotoxicity is toxicity in the kidneys.

Kidney failure

renal failurekidney problemsrenal impairment
The nephrotoxic effect of most drugs is more profound in patients already suffering from kidney failure.
The specific action on the kidneys is not fully understood, but may be due in part to nephrotoxic metabolites of myoglobin.

Amphotericin B

amphotericinliposomal amphotericin BAbelcet
Kidney damage is a frequently reported side effect, and can be severe and/or irreversible.

Vancomycin

Red man syndromeRed man syndrome (Drug eruption)Vancocin
* β-lactam antibiotics, vancomycin, rifampicin, sulphonamides, ciprofloxacin, NSAIDs, ranitidine, cimetidine, furosemide, thiazides, phenytoin.
Later trials using purer forms of vancomycin found nephrotoxicity is an infrequent adverse effect (0.1% to 1% of patients), but this is accentuated in the presence of aminoglycosides.

Rifampicin

rifampinRifadinRimactane
* β-lactam antibiotics, vancomycin, rifampicin, sulphonamides, ciprofloxacin, NSAIDs, ranitidine, cimetidine, furosemide, thiazides, phenytoin.
The treatment-related adverse effects include hepatotoxicity, nephrotoxicity, hemolysis, and interactions with other drugs.

Radiocontrast agent

radiocontrastcontrastcontrast agent
Iodinated contrast may be toxic to the kidneys, especially when given via the arteries prior to studies such as catheter coronary angiography.

Aristolochic acid

aristolochic acidsaristolochicaristolochin
Aristolochic acids are a family of carcinogenic, mutagenic, and nephrotoxic phytochemicals commonly found in the flowering plant family Aristolochiaceae (birthworts).

Aciclovir

acyclovirZoviraxAcihexal
Intravenous aciclovir may cause reversible nephrotoxicity in up to 5% to 10% of patients because of precipitation of aciclovir crystals in the kidney.

Furosemide

LasixDiucardinFlüssen
* β-lactam antibiotics, vancomycin, rifampicin, sulphonamides, ciprofloxacin, NSAIDs, ranitidine, cimetidine, furosemide, thiazides, phenytoin.

Renal function

glomerular filtration ratekidney functioncreatinine clearance
It is a poisonous effect of some substances, both toxic chemicals and medications, on renal function.
Hence, a more accurate glomerular filtration rate or its approximation using creatinine clearance is measured whenever renal disease is suspected or careful dosing of nephrotoxic drugs is required.

Orellanine

orellanin
Along with the isolation of orellanine, Grzymala was also able to demonstrate the nephrotoxicity of Cortinarius orellanus and determine various physical and chemical properties of orellanine.

Fumaric acid

fumaratefumaric acid esters(''E'')-butenedioic acid
The European Commission Scientific Committee on Animal Nutrition, part of DG Health, found in 2014 that fumaric acid is "practically non-toxic" but high doses are probably nephrotoxic after long-term use.

Cimetidine

TagametCimehexal
* β-lactam antibiotics, vancomycin, rifampicin, sulphonamides, ciprofloxacin, NSAIDs, ranitidine, cimetidine, furosemide, thiazides, phenytoin.
Metiamide was an effective agent; it was associated, however, with unacceptable nephrotoxicity and agranulocytosis.

Rhubarb

RheumRheum'' × ''hybridumR.'' × ''hybridum
Rhubarb leaves contain poisonous substances, including oxalic acid, which is a nephrotoxic acid that is present in many plants.

Kidney

kidneysrenalkidney disorder
Nephrotoxicity is toxicity in the kidneys.

Poison

poisonouspoisonstoxic substances
It is a poisonous effect of some substances, both toxic chemicals and medications, on renal function.

Chemical substance

chemicalchemicalssubstance
It is a poisonous effect of some substances, both toxic chemicals and medications, on renal function.

Medication

pharmaceuticalpharmaceuticalspharmaceutical drug
It is a poisonous effect of some substances, both toxic chemicals and medications, on renal function.

Heparin

unfractionated heparinHeparin sodiumVitrum AB
Nephrotoxicity should not be confused with the fact that some medications have a predominantly renal excretion and need their dose adjusted for the decreased renal function (e.g., heparin).

Diuretic